DE60002755D1 - Benzothiadiazinderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen - Google Patents

Benzothiadiazinderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen

Info

Publication number
DE60002755D1
DE60002755D1 DE60002755T DE60002755T DE60002755D1 DE 60002755 D1 DE60002755 D1 DE 60002755D1 DE 60002755 T DE60002755 T DE 60002755T DE 60002755 T DE60002755 T DE 60002755T DE 60002755 D1 DE60002755 D1 DE 60002755D1
Authority
DE
Germany
Prior art keywords
same
sub
production
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60002755T
Other languages
English (en)
Other versions
DE60002755T2 (de
Inventor
Bernard Pirotte
Tullio Pascal De
Stephane Boverie
Isabelle Kempen
Pierre Lestage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Servier SAS filed Critical Laboratoires Servier SAS
Application granted granted Critical
Publication of DE60002755D1 publication Critical patent/DE60002755D1/de
Publication of DE60002755T2 publication Critical patent/DE60002755T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE60002755T 1999-11-30 2000-11-28 Benzothiadiazinderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen Expired - Fee Related DE60002755T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9915034A FR2801587B1 (fr) 1999-11-30 1999-11-30 Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR9915034 1999-11-30
PCT/FR2000/003313 WO2001040210A1 (fr) 1999-11-30 2000-11-28 Nouveaux derives de benzothiadiazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
DE60002755D1 true DE60002755D1 (de) 2003-06-18
DE60002755T2 DE60002755T2 (de) 2004-04-29

Family

ID=9552685

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60002755T Expired - Fee Related DE60002755T2 (de) 1999-11-30 2000-11-28 Benzothiadiazinderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zusammensetzungen

Country Status (24)

Country Link
US (1) US6894043B1 (de)
EP (1) EP1233953B1 (de)
JP (1) JP2003515599A (de)
KR (1) KR100477385B1 (de)
CN (1) CN1162414C (de)
AT (1) ATE240306T1 (de)
AU (1) AU772641B2 (de)
BR (1) BR0015826A (de)
CA (1) CA2392929A1 (de)
DE (1) DE60002755T2 (de)
DK (1) DK1233953T3 (de)
EA (1) EA004053B1 (de)
ES (1) ES2199188T3 (de)
FR (1) FR2801587B1 (de)
HK (1) HK1052697B (de)
HU (1) HUP0204154A3 (de)
MX (1) MXPA02004593A (de)
NO (1) NO20022552L (de)
NZ (1) NZ519271A (de)
PL (1) PL355722A1 (de)
PT (1) PT1233953E (de)
SI (1) SI1233953T1 (de)
WO (1) WO2001040210A1 (de)
ZA (1) ZA200203305B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2833950B1 (fr) * 2001-12-21 2005-12-16 Servier Lab Nouveaux derives de benzothiazine et de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2854634B1 (fr) * 2003-05-05 2005-07-08 Servier Lab Nouveaux derives de thiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2865474B1 (fr) * 2004-01-26 2008-06-13 Servier Lab Nouveaux derives de benzothiazines fluorees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA2578224A1 (en) * 2004-08-25 2006-03-09 Essentialis, Inc. Pharmaceutical formulations of potassium atp channel openers and uses thereof
US20060063707A1 (en) * 2004-09-17 2006-03-23 Lifelike Biomatic, Inc. Compositions for enhancing memory and methods therefor
FR2877338B1 (fr) * 2004-11-03 2007-01-26 Servier Lab Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2877342B1 (fr) * 2004-11-03 2007-01-26 Servier Lab Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2879201B1 (fr) * 2004-12-10 2007-02-16 Servier Lab Nouveaux derives de benzothiazine et benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2006335153B2 (en) * 2006-01-05 2012-03-15 Essentialis, Inc. Salts of potassium ATP channel openers and uses thereof
KR100787130B1 (ko) * 2006-03-23 2007-12-21 한국화학연구원 신규의 치환된 1,1-다이옥소-벤조[1,2,4]티아디아진-3-온, 이의 제조방법 및 이를 포함하는 약학적 조성물
JP2010532383A (ja) * 2007-07-02 2010-10-07 エッセンシャリス，インク． カリウムａｔｐチャネル開口薬の塩およびその使用
WO2010054336A2 (en) * 2008-11-10 2010-05-14 The Regents Of The University Of California Therapeutic uses of ampa receptor modulators for treatment of motor dysfunction
BR112013002250B1 (pt) 2010-08-10 2020-10-27 Takeda Pharmaceutical Company Limited composto, composição farmacêutica, e, uso de um composto
CN102600171A (zh) * 2010-10-27 2012-07-25 北京理工大学 一类苯并噻二嗪和吡啶并噻二嗪衍生物作为醛糖还原酶抑制剂的结构、合成方法及用途
EP3215270B1 (de) * 2014-11-03 2020-05-27 The General Hospital Corporation Konzentration von partikeln in einer mikrofluidischen vorrichtung
CN111518058B (zh) * 2020-05-29 2021-03-09 四川大学华西医院 一种噁噻嗪类化合物及其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2690160A1 (fr) * 1992-04-15 1993-10-22 Rhone Poulenc Rorer Sa Application de dérivés d'acide 2H-1,2,4-benzothiadiazine-1,1-dioxyde-3-carboxylique à la préparation de médicaments, les produits nouveaux, leur préparation et les médicaments les contenant.
CA2130096A1 (fr) * 1992-04-15 1993-10-28 Jean-Claude Aloup Derives d'acide 3,4-dihydro-2h-1,2,4-benzothiadiazine 1,1-dioxyde-3-carboxylique, leur preparation et les medicaments les contenant
FR2710062B1 (fr) * 1993-09-17 1995-12-01 Rhone Poulenc Rorer Sa Dérivés d'acide 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxyde-3-carboxylique, leur préparation et les médicaments les contenant.
AU4345297A (en) * 1996-09-17 1998-04-14 Regents Of The University Of California, The Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor

Also Published As

Publication number Publication date
FR2801587A1 (fr) 2001-06-01
HUP0204154A3 (en) 2006-01-30
SI1233953T1 (en) 2003-10-31
ATE240306T1 (de) 2003-05-15
BR0015826A (pt) 2002-07-30
CN1402717A (zh) 2003-03-12
DE60002755T2 (de) 2004-04-29
PL355722A1 (en) 2004-05-17
CA2392929A1 (fr) 2001-06-07
HK1052697B (zh) 2005-02-08
NO20022552L (no) 2002-07-11
KR20020058047A (ko) 2002-07-12
WO2001040210A1 (fr) 2001-06-07
NZ519271A (en) 2004-02-27
HUP0204154A2 (hu) 2003-03-28
NO20022552D0 (no) 2002-05-29
AU772641B2 (en) 2004-05-06
PT1233953E (pt) 2003-08-29
ES2199188T3 (es) 2004-02-16
EP1233953B1 (de) 2003-05-14
JP2003515599A (ja) 2003-05-07
MXPA02004593A (es) 2002-09-02
DK1233953T3 (da) 2003-08-11
ZA200203305B (en) 2003-06-25
EP1233953A1 (de) 2002-08-28
CN1162414C (zh) 2004-08-18
US6894043B1 (en) 2005-05-17
EA200200489A1 (ru) 2002-10-31
KR100477385B1 (ko) 2005-03-17
AU1870401A (en) 2001-06-12
FR2801587B1 (fr) 2002-01-11
EA004053B1 (ru) 2003-12-25
HK1052697A1 (en) 2003-09-26

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee