DE4113174A1 - Vorrichtung und verfahren zur trocknung biologischer proben - Google Patents
Vorrichtung und verfahren zur trocknung biologischer probenInfo
- Publication number
- DE4113174A1 DE4113174A1 DE4113174A DE4113174A DE4113174A1 DE 4113174 A1 DE4113174 A1 DE 4113174A1 DE 4113174 A DE4113174 A DE 4113174A DE 4113174 A DE4113174 A DE 4113174A DE 4113174 A1 DE4113174 A1 DE 4113174A1
- Authority
- DE
- Germany
- Prior art keywords
- sample
- drying chamber
- vacuum
- drying
- chamber
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000001035 drying Methods 0.000 title claims description 95
- 238000000034 method Methods 0.000 title claims description 14
- 239000012472 biological sample Substances 0.000 title claims description 7
- 239000000523 sample Substances 0.000 claims description 77
- 239000002904 solvent Substances 0.000 claims description 61
- 239000012620 biological material Substances 0.000 claims description 19
- 238000009833 condensation Methods 0.000 claims description 19
- 230000005494 condensation Effects 0.000 claims description 19
- 239000007789 gas Substances 0.000 claims description 16
- 230000001105 regulatory effect Effects 0.000 claims description 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 7
- 230000000903 blocking effect Effects 0.000 claims description 7
- 238000001704 evaporation Methods 0.000 claims description 6
- 239000011261 inert gas Substances 0.000 claims description 4
- 230000008020 evaporation Effects 0.000 claims description 3
- 229910052757 nitrogen Inorganic materials 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 238000001816 cooling Methods 0.000 description 7
- 239000000463 material Substances 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 238000009423 ventilation Methods 0.000 description 4
- 238000011084 recovery Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000001291 vacuum drying Methods 0.000 description 3
- 239000003570 air Substances 0.000 description 2
- 239000012080 ambient air Substances 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 230000007797 corrosion Effects 0.000 description 2
- 241000589614 Pseudomonas stutzeri Species 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 238000004817 gas chromatography Methods 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000007790 scraping Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B5/00—Drying solid materials or objects by processes not involving the application of heat
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B25/00—Details of general application not covered by group F26B21/00 or F26B23/00
- F26B25/005—Treatment of dryer exhaust gases
- F26B25/006—Separating volatiles, e.g. recovering solvents from dryer exhaust gases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4022—Concentrating samples by thermal techniques; Phase changes
- G01N2001/4027—Concentrating samples by thermal techniques; Phase changes evaporation leaving a concentrated sample
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00495—Centrifuges
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S159/00—Concentrating evaporators
- Y10S159/16—Vacuum
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Drying Of Solid Materials (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/549,447 US5137604A (en) | 1990-07-06 | 1990-07-06 | Apparatus for drying biological specimens |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE4113174A1 true DE4113174A1 (de) | 1992-01-16 |
| DE4113174C2 DE4113174C2 (https=) | 1993-06-17 |
Family
ID=24193069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE4113174A Granted DE4113174A1 (de) | 1990-07-06 | 1991-04-23 | Vorrichtung und verfahren zur trocknung biologischer proben |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US5137604A (https=) |
| DE (1) | DE4113174A1 (https=) |
| FR (1) | FR2664367B1 (https=) |
| GB (1) | GB2246192A (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999033538A1 (en) * | 1997-12-23 | 1999-07-08 | Michael Cole | Evaporator and evaporation process |
| DE19841556C1 (de) * | 1998-09-11 | 2000-03-23 | Volker Barkey | Eindampf-Vorrichtung für flüssiges Probenmaterial |
| US7555933B2 (en) | 2006-08-01 | 2009-07-07 | Thermo Fisher Scientific Inc. | Method and software for detecting vacuum concentrator ends-of-runs |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5217572A (en) * | 1989-03-20 | 1993-06-08 | Jouan | Centrifugal evaporator-concentrator for concentrating specimens by evaporation of the solvent |
| US5211808A (en) * | 1990-11-13 | 1993-05-18 | Savant Instruments | Microwave heating in a vacuum centrifugal concentrator |
| US5334130A (en) * | 1992-05-13 | 1994-08-02 | Savant Instruments, Inc. | Centrifugal vacuum concentration with holder assembly |
| US5289641A (en) * | 1992-11-23 | 1994-03-01 | Welch Vacuum Technology, Inc. | Chemical vapor trap and vacuum drying system including same |
| DE19627641C1 (de) * | 1996-07-09 | 1998-01-15 | Heinz Dipl Ing Ploechinger | Verfahren und Vorrichtung zum Steuern des Drucks in einer Vakuumkammer einer Destillations- oder Sublimations-Vorrichtung |
| US20020111714A1 (en) * | 1997-12-23 | 2002-08-15 | Duncan Guthrie | Centrifugal evaporator |
| GB9803684D0 (en) * | 1998-02-24 | 1998-04-15 | Genevac Ltd | Method and apparatus for controlling temperature during evaporation of samples |
| FR2789189B1 (fr) * | 1999-02-02 | 2002-12-13 | Air Liquide Sante France | Procede et installation de regulation d'une centrale de production de vide medical |
| EP1153278B1 (en) * | 1999-02-09 | 2006-06-21 | Genevac Limited | Improved vacuum control in evaporators |
| DE19938946C2 (de) * | 1999-08-17 | 2001-11-22 | Helmut Herz | Verfahren und Einrichtung zum Konzentrieren einer Lösungsprobe |
| DE10008023A1 (de) * | 2000-02-22 | 2001-08-23 | Qiagen Gmbh | Vorrichtung zum Filtern und Beseitigen von Flüssigkeiten |
| DE10103441B4 (de) * | 2001-01-25 | 2005-09-08 | Helmut Siegel | Verfahren zur Synthese von lösemittelhaltigen Stoffgemischen |
| GB0225329D0 (en) | 2002-10-31 | 2002-12-11 | Genevac Ltd | Pressure control in centrifugal evaporators |
| US6892471B2 (en) * | 2003-07-02 | 2005-05-17 | Anders T. Ragnarsson | Sludge dryer |
| US20100155635A1 (en) * | 2008-12-22 | 2010-06-24 | Giovanni Fima | Systems & Methods For Monitoring And Controlling Water Consumption |
| DE102017130785A1 (de) * | 2017-12-20 | 2019-06-27 | Eppendorf Ag | Temperierte Zentrifuge |
| GB201819417D0 (en) * | 2018-11-29 | 2019-01-16 | Quantumdx Group Ltd | Vacuum-assisted drying of filters in microfluidic systems |
| CN114597315A (zh) * | 2020-12-04 | 2022-06-07 | 中国科学院大连化学物理研究所 | 一种适用于制备钙钛矿薄膜的真空闪蒸及退火集成系统 |
| CN115881507B (zh) * | 2022-12-30 | 2025-12-23 | 中元汇吉生物技术股份有限公司 | 气路结构、干靶装置减压方法及干靶装置 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4226669A (en) * | 1979-05-09 | 1980-10-07 | Savant Instruments, Inc. | Vacuum centrifuge with magnetic drive |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE413166A (https=) * | ||||
| USRE16640E (en) * | 1924-05-01 | 1927-05-31 | Sionobs to the bhabples | |
| FR1230874A (fr) * | 1958-07-23 | 1960-09-20 | Leybold Hochvakuum Anlagen | Procédé et dispositif pour extraire d'un récipient par pompage de grandes quantités de vapeurs condensables |
| DE1135829B (de) * | 1959-12-19 | 1962-08-30 | Leybold Hochvakuum Anlagen | Vakuum-Trocknungsverfahren fuer kapillarporoes oder durch Diffusion trocknende Gueter |
| FR1275104A (fr) * | 1960-10-24 | 1961-11-03 | Leybold Hochvakuum Anlagen | Procédé et dispositif pour le séchage de matières par capillarité ou diffusion |
| DE1196578B (de) * | 1962-02-27 | 1965-07-08 | Leybold Hochvakuum Anlagen | Gefriertrocknungsverfahren mit Rueckgewinn dabei fluechtiger Bestandteile |
| DE1286785B (de) * | 1964-06-10 | 1969-01-09 | Heraeus Christ Gmbh | Vakuumzentrifuge |
| US3304990A (en) * | 1965-02-15 | 1967-02-21 | Univ Tennessee Res Corp | Explosion proof centrifugal evaporator with magnetic drive |
| US3574949A (en) * | 1969-04-01 | 1971-04-13 | Frederick R Furth | Lumber drying |
| ES404902A1 (es) * | 1972-07-06 | 1975-06-16 | Grifols Sa Lab | Procedimiento para concentrar liquidos termolabiles, espe- cialmente biologicos. |
| US3977935A (en) * | 1974-09-25 | 1976-08-31 | Allen Avinoam Kowarski | Method and apparatus for evaporating liquids |
| SE410868B (sv) * | 1978-04-12 | 1979-11-12 | Lumalampan Ab | Sett och anordning for att separera kvicksilver fran fast material genom destillation under vacuum |
| US4367666A (en) * | 1980-12-01 | 1983-01-11 | Cubic Western Data | Ticket stock feed and shear system |
| US4467532A (en) * | 1983-01-06 | 1984-08-28 | Drake Harry W | Apparatus and process for drying lumber |
| DE3471367D1 (en) * | 1983-12-19 | 1988-06-23 | Duphar Int Res | Method of drying a solid and device therefor |
| US4613412A (en) * | 1984-11-26 | 1986-09-23 | Wastesaver Corporation | Evacuator system and process for an evaporative recovery system |
| FR2602662A1 (fr) * | 1986-07-28 | 1988-02-19 | Abry Yves | Procede et dispositif pour le sechage de chaussures par le vide |
| US4929312A (en) * | 1988-01-27 | 1990-05-29 | Westcott Robert D | Solvent recovery apparatus and method |
| US4857811A (en) * | 1988-03-31 | 1989-08-15 | E. I. Du Pont De Nemours And Company | Evacuation pump control for a centrifuge instrument |
| US4913771A (en) * | 1988-11-25 | 1990-04-03 | Mcintyre Glover C | Method for dewatering sludge or slurry |
| US5025571A (en) * | 1990-04-25 | 1991-06-25 | Savant Instruments, Inc. | Vacuum pump with heated vapor pre-trap |
-
1990
- 1990-07-06 US US07/549,447 patent/US5137604A/en not_active Expired - Lifetime
- 1990-11-07 GB GB9024154A patent/GB2246192A/en not_active Withdrawn
-
1991
- 1991-04-23 DE DE4113174A patent/DE4113174A1/de active Granted
- 1991-07-04 FR FR9108377A patent/FR2664367B1/fr not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4226669A (en) * | 1979-05-09 | 1980-10-07 | Savant Instruments, Inc. | Vacuum centrifuge with magnetic drive |
| US4226669B1 (https=) * | 1979-05-09 | 1990-10-16 | Savant Holdings Inc |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999033538A1 (en) * | 1997-12-23 | 1999-07-08 | Michael Cole | Evaporator and evaporation process |
| US6682631B2 (en) | 1997-12-23 | 2004-01-27 | Genevac Limited | Evaporator and evaporation process |
| DE19841556C1 (de) * | 1998-09-11 | 2000-03-23 | Volker Barkey | Eindampf-Vorrichtung für flüssiges Probenmaterial |
| US7555933B2 (en) | 2006-08-01 | 2009-07-07 | Thermo Fisher Scientific Inc. | Method and software for detecting vacuum concentrator ends-of-runs |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2246192A (en) | 1992-01-22 |
| GB9024154D0 (en) | 1990-12-19 |
| FR2664367B1 (fr) | 1993-10-15 |
| FR2664367A1 (fr) | 1992-01-10 |
| DE4113174C2 (https=) | 1993-06-17 |
| US5137604A (en) | 1992-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| 8125 | Change of the main classification |
Ipc: F26B 5/04 |
|
| D2 | Grant after examination | ||
| 8381 | Inventor (new situation) |
Free format text: ZLOBINSKY, YURY, MASSAPEQUA, N.Y., US MEEKS, WARREN, COLUMBIA, MD., US |
|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: THERMO SAVANT, FARMINGDALE, N.Y., US |
|
| 8328 | Change in the person/name/address of the agent |
Free format text: SCHUHMANN, A., RECHTSANW., 90461 NUERNBERG |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: THERMO SAVANT INC., HOLBROOK, N.Y., US |
|
| R071 | Expiry of right |