DE3878708T2 - Thiazolderivate mit aktivitaet auf das cholinergische system, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents
Thiazolderivate mit aktivitaet auf das cholinergische system, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.Info
- Publication number
- DE3878708T2 DE3878708T2 DE8888400572T DE3878708T DE3878708T2 DE 3878708 T2 DE3878708 T2 DE 3878708T2 DE 8888400572 T DE8888400572 T DE 8888400572T DE 3878708 T DE3878708 T DE 3878708T DE 3878708 T2 DE3878708 T2 DE 3878708T2
- Authority
- DE
- Germany
- Prior art keywords
- activity
- production
- pharmaceutical compositions
- compositions containing
- thiazole derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/84—Naphthothiazoles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8703398A FR2612187B1 (fr) | 1987-03-12 | 1987-03-12 | Derives du thiazole actifs sur le systeme cholinergique, leur procede de preparation et compositions pharmaceutiques en contenant |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3878708D1 DE3878708D1 (de) | 1993-04-08 |
DE3878708T2 true DE3878708T2 (de) | 1993-09-02 |
Family
ID=9348897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8888400572T Expired - Fee Related DE3878708T2 (de) | 1987-03-12 | 1988-03-11 | Thiazolderivate mit aktivitaet auf das cholinergische system, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP0283390B1 (de) |
JP (1) | JPS63243080A (de) |
KR (1) | KR880011135A (de) |
AR (1) | AR243515A1 (de) |
AT (1) | ATE86249T1 (de) |
AU (1) | AU612350B2 (de) |
DD (1) | DD274028A5 (de) |
DE (1) | DE3878708T2 (de) |
DK (1) | DK170162B1 (de) |
ES (1) | ES2053778T3 (de) |
FI (1) | FI881152A (de) |
FR (1) | FR2612187B1 (de) |
HU (1) | HU198916B (de) |
IE (1) | IE60173B1 (de) |
IL (1) | IL85704A (de) |
MA (1) | MA21207A1 (de) |
MY (1) | MY103233A (de) |
NO (1) | NO170081C (de) |
NZ (1) | NZ223845A (de) |
OA (1) | OA08871A (de) |
PH (1) | PH25389A (de) |
PL (1) | PL151889B1 (de) |
PT (1) | PT86952B (de) |
SU (1) | SU1604157A3 (de) |
TN (1) | TNSN88020A1 (de) |
YU (1) | YU49688A (de) |
ZA (1) | ZA881764B (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6440474A (en) * | 1987-08-04 | 1989-02-10 | Hisamitsu Pharmaceutical Co | Novel 2-substituted aminothiazole derivative |
JPH0753666B2 (ja) * | 1987-09-14 | 1995-06-07 | 久光製薬株式会社 | 置換ジフェニルチアゾール誘導体からなる抗炎症剤 |
FR2656610B1 (fr) * | 1989-12-29 | 1992-05-07 | Sanofi Sa | Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique. |
EP0535227A4 (en) * | 1990-05-29 | 1993-08-18 | Nippon Soda Co., Ltd. | N-substituted heterocyclic amidine derivative |
WO1992021666A1 (fr) * | 1991-05-31 | 1992-12-10 | Laboratoires Upsa | Derives de thiazole antagonistes de recepteurs a l'angiotensine ii |
FR2677021B1 (fr) * | 1991-05-31 | 1993-10-01 | Upsa Laboratoires | Nouveaux derives de thiazole antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
FR2692893B1 (fr) * | 1992-06-24 | 1994-09-02 | Sanofi Elf | Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
AU4982293A (en) * | 1993-03-02 | 1994-09-26 | Fujisawa Pharmaceutical Co., Ltd. | Novel heterocyclic compound |
FR2714059B1 (fr) * | 1993-12-21 | 1996-03-08 | Sanofi Elf | Dérivés amino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
FR2735777B1 (fr) * | 1995-06-21 | 1997-09-12 | Sanofi Sa | Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
FR2754258B1 (fr) * | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
GB9705428D0 (en) * | 1997-03-15 | 1997-04-30 | Knoll Ag | Therapeutic agents |
ES2237919T4 (es) * | 1998-06-18 | 2007-05-01 | Bristol-Myers Squibb Company | Inhibidores aminotiazol sustituidos con carbono de quinasas dependientes de ciclina. |
US6218408B1 (en) | 1999-06-30 | 2001-04-17 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (bicyclics) |
US6989379B1 (en) | 1999-04-22 | 2006-01-24 | H. Lundbick A/S | Selective NPY (Y5) antagonists |
ATE361917T1 (de) | 1999-04-22 | 2007-06-15 | Lundbeck & Co As H | Selektive npy(y5)-antagonisten |
US6340683B1 (en) | 1999-04-22 | 2002-01-22 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (triazines) |
US6214853B1 (en) | 1999-06-30 | 2001-04-10 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (bicyclics) |
US6225330B1 (en) | 1999-06-30 | 2001-05-01 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
US6222040B1 (en) | 1999-06-30 | 2001-04-24 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
US7273880B2 (en) | 1999-06-30 | 2007-09-25 | H. Lunbeck A/S | Selective NPY (Y5) antagonists |
WO2002083863A2 (en) | 2001-04-17 | 2002-10-24 | Sepracor, Inc. | Thiazole and other heterocyclic ligands and use thereof |
CA2471989A1 (en) * | 2002-01-16 | 2003-07-31 | University Of Virginia Patent Foundation | 2-aminothiazole allosteric enhancers of a1 adenosine receptors |
DE10251513A1 (de) * | 2002-11-04 | 2004-05-19 | Basf Ag | Übergangsmetallkatalysatoren für (Co)Polymerisation von olefinischen Monomeren |
JP2007261945A (ja) * | 2004-04-07 | 2007-10-11 | Taisho Pharmaceut Co Ltd | チアゾール誘導体 |
WO2006130493A2 (en) * | 2005-05-31 | 2006-12-07 | Vertex Pharmaceuticals Incorporated | Heterocycles useful as modulators of ion channels |
KR20110137941A (ko) * | 2010-06-18 | 2011-12-26 | (주) 에빅스젠 | 신규한 티오우레아 또는 우레아 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 aids 예방 또는 치료용 약학 조성물 |
RU2456284C1 (ru) * | 2011-04-12 | 2012-07-20 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Уральский федеральный университет имени первого Президента России Б.Н. Ельцина" | 2-аминопропилморфолино-5-арил-6н-1,3,4-тиадиазины, дигидробромиды и 2-аминопропилморфолино-4-арилтиазолы, гидробромиды, обладающие антиагрегантным действием |
WO2016077232A2 (en) | 2014-11-10 | 2016-05-19 | Forge Life Science, Llc | Anti-hcmv compositions and methods |
CN115160207B (zh) * | 2022-04-21 | 2023-09-26 | 烟台大学 | 苯甲酰硫脲类化合物及其制备方法和赤潮藻杀藻剂的应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2975182A (en) * | 1959-11-16 | 1961-03-14 | Paul A J Janssen | 1-(aroylalkyl)-4-(heterocyclyl) piperazines |
FR2092714B1 (de) * | 1970-06-11 | 1974-03-22 | Melle Bezons | |
CH583232A5 (de) * | 1973-02-02 | 1976-12-31 | Wander Ag Dr A | |
DE3135250A1 (de) * | 1981-09-05 | 1983-03-17 | Basf Ag, 6700 Ludwigshafen | Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
US4552886A (en) * | 1982-06-07 | 1985-11-12 | Eli Lilly And Company | Fungicidal pyridylmethyl-amines |
FR2581063B1 (fr) * | 1985-04-30 | 1987-07-17 | Chauvin Blache Lab | Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique |
HUT43600A (en) * | 1985-06-22 | 1987-11-30 | Sandoz Ag | Process for production of new thiazole derivatives and medical compound containing those |
-
1987
- 1987-03-12 FR FR8703398A patent/FR2612187B1/fr not_active Expired
-
1988
- 1988-03-03 AU AU12662/88A patent/AU612350B2/en not_active Ceased
- 1988-03-08 DD DD88313502A patent/DD274028A5/de not_active IP Right Cessation
- 1988-03-08 MA MA21448A patent/MA21207A1/fr unknown
- 1988-03-09 PH PH36616A patent/PH25389A/en unknown
- 1988-03-09 DK DK128688A patent/DK170162B1/da not_active IP Right Cessation
- 1988-03-10 AR AR88310267A patent/AR243515A1/es active
- 1988-03-10 NZ NZ223845A patent/NZ223845A/en unknown
- 1988-03-11 OA OA59299A patent/OA08871A/xx unknown
- 1988-03-11 ZA ZA881764A patent/ZA881764B/xx unknown
- 1988-03-11 AT AT88400572T patent/ATE86249T1/de not_active IP Right Cessation
- 1988-03-11 IE IE72188A patent/IE60173B1/en not_active IP Right Cessation
- 1988-03-11 DE DE8888400572T patent/DE3878708T2/de not_active Expired - Fee Related
- 1988-03-11 YU YU00496/88A patent/YU49688A/xx unknown
- 1988-03-11 PT PT86952A patent/PT86952B/pt not_active IP Right Cessation
- 1988-03-11 HU HU881190A patent/HU198916B/hu not_active IP Right Cessation
- 1988-03-11 PL PL1988271132A patent/PL151889B1/pl unknown
- 1988-03-11 MY MYPI88000258A patent/MY103233A/en unknown
- 1988-03-11 TN TNTNSN88020A patent/TNSN88020A1/fr unknown
- 1988-03-11 ES ES88400572T patent/ES2053778T3/es not_active Expired - Lifetime
- 1988-03-11 NO NO881093A patent/NO170081C/no unknown
- 1988-03-11 SU SU884355377A patent/SU1604157A3/ru active
- 1988-03-11 IL IL85704A patent/IL85704A/xx unknown
- 1988-03-11 FI FI881152A patent/FI881152A/fi not_active Application Discontinuation
- 1988-03-11 EP EP88400572A patent/EP0283390B1/de not_active Expired - Lifetime
- 1988-03-12 JP JP63059223A patent/JPS63243080A/ja active Pending
- 1988-03-12 KR KR1019880002614A patent/KR880011135A/ko not_active Application Discontinuation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |