ATE86249T1 - Thiazolderivate mit aktivitaet auf das cholinergische system, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. - Google Patents
Thiazolderivate mit aktivitaet auf das cholinergische system, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen.Info
- Publication number
- ATE86249T1 ATE86249T1 AT88400572T AT88400572T ATE86249T1 AT E86249 T1 ATE86249 T1 AT E86249T1 AT 88400572 T AT88400572 T AT 88400572T AT 88400572 T AT88400572 T AT 88400572T AT E86249 T1 ATE86249 T1 AT E86249T1
- Authority
- AT
- Austria
- Prior art keywords
- activity
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/84—Naphthothiazoles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8703398A FR2612187B1 (fr) | 1987-03-12 | 1987-03-12 | Derives du thiazole actifs sur le systeme cholinergique, leur procede de preparation et compositions pharmaceutiques en contenant |
EP88400572A EP0283390B1 (de) | 1987-03-12 | 1988-03-11 | Thiazolderivate mit Aktivität auf das cholinergische System, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammenstellungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE86249T1 true ATE86249T1 (de) | 1993-03-15 |
Family
ID=9348897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88400572T ATE86249T1 (de) | 1987-03-12 | 1988-03-11 | Thiazolderivate mit aktivitaet auf das cholinergische system, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammenstellungen. |
Country Status (27)
Country | Link |
---|---|
EP (1) | EP0283390B1 (de) |
JP (1) | JPS63243080A (de) |
KR (1) | KR880011135A (de) |
AR (1) | AR243515A1 (de) |
AT (1) | ATE86249T1 (de) |
AU (1) | AU612350B2 (de) |
DD (1) | DD274028A5 (de) |
DE (1) | DE3878708T2 (de) |
DK (1) | DK170162B1 (de) |
ES (1) | ES2053778T3 (de) |
FI (1) | FI881152A (de) |
FR (1) | FR2612187B1 (de) |
HU (1) | HU198916B (de) |
IE (1) | IE60173B1 (de) |
IL (1) | IL85704A (de) |
MA (1) | MA21207A1 (de) |
MY (1) | MY103233A (de) |
NO (1) | NO170081C (de) |
NZ (1) | NZ223845A (de) |
OA (1) | OA08871A (de) |
PH (1) | PH25389A (de) |
PL (1) | PL151889B1 (de) |
PT (1) | PT86952B (de) |
SU (1) | SU1604157A3 (de) |
TN (1) | TNSN88020A1 (de) |
YU (1) | YU49688A (de) |
ZA (1) | ZA881764B (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6440474A (en) * | 1987-08-04 | 1989-02-10 | Hisamitsu Pharmaceutical Co | Novel 2-substituted aminothiazole derivative |
JPH0753666B2 (ja) * | 1987-09-14 | 1995-06-07 | 久光製薬株式会社 | 置換ジフェニルチアゾール誘導体からなる抗炎症剤 |
FR2656610B1 (fr) * | 1989-12-29 | 1992-05-07 | Sanofi Sa | Derives d'amino-2 phenyl-4 thiazole, leur procede de preparation et leur application therapeutique. |
EP0535227A4 (en) * | 1990-05-29 | 1993-08-18 | Nippon Soda Co., Ltd. | N-substituted heterocyclic amidine derivative |
FR2677021B1 (fr) * | 1991-05-31 | 1993-10-01 | Upsa Laboratoires | Nouveaux derives de thiazole antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant. |
WO1992021666A1 (fr) * | 1991-05-31 | 1992-12-10 | Laboratoires Upsa | Derives de thiazole antagonistes de recepteurs a l'angiotensine ii |
FR2692893B1 (fr) * | 1992-06-24 | 1994-09-02 | Sanofi Elf | Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
AU4982293A (en) * | 1993-03-02 | 1994-09-26 | Fujisawa Pharmaceutical Co., Ltd. | Novel heterocyclic compound |
FR2714059B1 (fr) * | 1993-12-21 | 1996-03-08 | Sanofi Elf | Dérivés amino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent. |
FR2735777B1 (fr) * | 1995-06-21 | 1997-09-12 | Sanofi Sa | Derives de 4-phenylaminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
FR2754258B1 (fr) * | 1996-10-08 | 1998-12-31 | Sanofi Sa | Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant |
GB9705428D0 (en) * | 1997-03-15 | 1997-04-30 | Knoll Ag | Therapeutic agents |
ES2237919T4 (es) * | 1998-06-18 | 2007-05-01 | Bristol-Myers Squibb Company | Inhibidores aminotiazol sustituidos con carbono de quinasas dependientes de ciclina. |
US6218408B1 (en) | 1999-06-30 | 2001-04-17 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (bicyclics) |
US6989379B1 (en) | 1999-04-22 | 2006-01-24 | H. Lundbick A/S | Selective NPY (Y5) antagonists |
WO2000064880A1 (en) | 1999-04-22 | 2000-11-02 | Synaptic Pharmaceutical Corporation | Selective npy (y5) antagonists |
US6340683B1 (en) | 1999-04-22 | 2002-01-22 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (triazines) |
US6214853B1 (en) | 1999-06-30 | 2001-04-10 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (bicyclics) |
US6222040B1 (en) | 1999-06-30 | 2001-04-24 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
US6225330B1 (en) | 1999-06-30 | 2001-05-01 | Synaptic Pharmaceutical Corporation | Selective NPY (Y5) antagonists (tricyclics) |
US7273880B2 (en) | 1999-06-30 | 2007-09-25 | H. Lunbeck A/S | Selective NPY (Y5) antagonists |
WO2002083863A2 (en) | 2001-04-17 | 2002-10-24 | Sepracor, Inc. | Thiazole and other heterocyclic ligands and use thereof |
EP1583530A4 (de) * | 2002-01-16 | 2008-07-23 | Univ Virginia | 2-aminothiazol-allosterische verstärker von a1-adenosin-rezeptoren |
DE10251513A1 (de) * | 2002-11-04 | 2004-05-19 | Basf Ag | Übergangsmetallkatalysatoren für (Co)Polymerisation von olefinischen Monomeren |
JP2007261945A (ja) * | 2004-04-07 | 2007-10-11 | Taisho Pharmaceut Co Ltd | チアゾール誘導体 |
JP5388574B2 (ja) * | 2005-05-31 | 2014-01-15 | バーテックス ファーマシューティカルズ インコーポレイテッド | イオンチャネルのモジュレーターとして有用なヘテロ環式類 |
KR20110137941A (ko) * | 2010-06-18 | 2011-12-26 | (주) 에빅스젠 | 신규한 티오우레아 또는 우레아 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 aids 예방 또는 치료용 약학 조성물 |
RU2456284C1 (ru) * | 2011-04-12 | 2012-07-20 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Уральский федеральный университет имени первого Президента России Б.Н. Ельцина" | 2-аминопропилморфолино-5-арил-6н-1,3,4-тиадиазины, дигидробромиды и 2-аминопропилморфолино-4-арилтиазолы, гидробромиды, обладающие антиагрегантным действием |
IL308138A (en) | 2014-11-10 | 2023-12-01 | Evrys Bio Llc | Preparations against human cytomegalovirus and methods of treating it |
CN115160207B (zh) * | 2022-04-21 | 2023-09-26 | 烟台大学 | 苯甲酰硫脲类化合物及其制备方法和赤潮藻杀藻剂的应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2975182A (en) * | 1959-11-16 | 1961-03-14 | Paul A J Janssen | 1-(aroylalkyl)-4-(heterocyclyl) piperazines |
FR2092714B1 (de) * | 1970-06-11 | 1974-03-22 | Melle Bezons | |
CH583232A5 (de) * | 1973-02-02 | 1976-12-31 | Wander Ag Dr A | |
DE3135250A1 (de) * | 1981-09-05 | 1983-03-17 | Basf Ag, 6700 Ludwigshafen | Tricyclische thiazolyloxamate, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel |
US4552886A (en) * | 1982-06-07 | 1985-11-12 | Eli Lilly And Company | Fungicidal pyridylmethyl-amines |
FR2581063B1 (fr) * | 1985-04-30 | 1987-07-17 | Chauvin Blache Lab | Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique |
NL8601494A (nl) * | 1985-06-22 | 1987-01-16 | Sandoz Ag | Thiazolen, hun bereiding en farmaceutische preparaten die ze bevatten. |
-
1987
- 1987-03-12 FR FR8703398A patent/FR2612187B1/fr not_active Expired
-
1988
- 1988-03-03 AU AU12662/88A patent/AU612350B2/en not_active Ceased
- 1988-03-08 DD DD88313502A patent/DD274028A5/de not_active IP Right Cessation
- 1988-03-08 MA MA21448A patent/MA21207A1/fr unknown
- 1988-03-09 PH PH36616A patent/PH25389A/en unknown
- 1988-03-09 DK DK128688A patent/DK170162B1/da not_active IP Right Cessation
- 1988-03-10 NZ NZ223845A patent/NZ223845A/en unknown
- 1988-03-10 AR AR88310267A patent/AR243515A1/es active
- 1988-03-11 AT AT88400572T patent/ATE86249T1/de not_active IP Right Cessation
- 1988-03-11 SU SU884355377A patent/SU1604157A3/ru active
- 1988-03-11 MY MYPI88000258A patent/MY103233A/en unknown
- 1988-03-11 NO NO881093A patent/NO170081C/no unknown
- 1988-03-11 PL PL1988271132A patent/PL151889B1/pl unknown
- 1988-03-11 DE DE8888400572T patent/DE3878708T2/de not_active Expired - Fee Related
- 1988-03-11 TN TNTNSN88020A patent/TNSN88020A1/fr unknown
- 1988-03-11 IE IE72188A patent/IE60173B1/en not_active IP Right Cessation
- 1988-03-11 FI FI881152A patent/FI881152A/fi not_active Application Discontinuation
- 1988-03-11 ES ES88400572T patent/ES2053778T3/es not_active Expired - Lifetime
- 1988-03-11 IL IL85704A patent/IL85704A/xx unknown
- 1988-03-11 EP EP88400572A patent/EP0283390B1/de not_active Expired - Lifetime
- 1988-03-11 ZA ZA881764A patent/ZA881764B/xx unknown
- 1988-03-11 OA OA59299A patent/OA08871A/xx unknown
- 1988-03-11 PT PT86952A patent/PT86952B/pt not_active IP Right Cessation
- 1988-03-11 YU YU00496/88A patent/YU49688A/xx unknown
- 1988-03-11 HU HU881190A patent/HU198916B/hu not_active IP Right Cessation
- 1988-03-12 KR KR1019880002614A patent/KR880011135A/ko not_active Application Discontinuation
- 1988-03-12 JP JP63059223A patent/JPS63243080A/ja active Pending
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |