DE3876124T2 - Immunoassay fuer thrombomodulin. - Google Patents

Immunoassay fuer thrombomodulin.

Info

Publication number
DE3876124T2
DE3876124T2 DE19883876124 DE3876124T DE3876124T2 DE 3876124 T2 DE3876124 T2 DE 3876124T2 DE 19883876124 DE19883876124 DE 19883876124 DE 3876124 T DE3876124 T DE 3876124T DE 3876124 T2 DE3876124 T2 DE 3876124T2
Authority
DE
Germany
Prior art keywords
thrombomodulin
antibody
human thrombomodulin
binding
thrombin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE19883876124
Other languages
German (de)
English (en)
Other versions
DE3876124D1 (en
Inventor
Hidemi Ishii
Mutsuyoshi Kazama
Masahiko Nakano
Jiro Tsubouchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Gas Chemical Co Inc
Original Assignee
Mitsubishi Gas Chemical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Gas Chemical Co Inc filed Critical Mitsubishi Gas Chemical Co Inc
Application granted granted Critical
Publication of DE3876124D1 publication Critical patent/DE3876124D1/de
Publication of DE3876124T2 publication Critical patent/DE3876124T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/7452—Thrombomodulin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DE19883876124 1987-04-01 1988-03-29 Immunoassay fuer thrombomodulin. Expired - Fee Related DE3876124T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7750787 1987-04-01

Publications (2)

Publication Number Publication Date
DE3876124D1 DE3876124D1 (en) 1993-01-07
DE3876124T2 true DE3876124T2 (de) 1993-05-06

Family

ID=13635877

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19883876124 Expired - Fee Related DE3876124T2 (de) 1987-04-01 1988-03-29 Immunoassay fuer thrombomodulin.

Country Status (3)

Country Link
EP (1) EP0285511B1 (enExample)
JP (1) JPS6447391A (enExample)
DE (1) DE3876124T2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6445398A (en) * 1987-08-13 1989-02-17 Kowa Co Antithrombin-binding substance monoclonal antibody, hybridoma producing said antibody and method for purifying and measuring thrombin-binding substance utilizing said monoclonal antibody
JP2509001B2 (ja) * 1989-11-02 1996-06-19 帝人株式会社 ヒト・トロンボモジユリンの免疫学的測定方法、そのための試薬及びそのためのキツト
WO1991006857A1 (en) * 1989-11-02 1991-05-16 Teijin Limited Immunoassay of human thrombomodulin, and reagent and kit therefor
JPH0736019B2 (ja) * 1989-12-27 1995-04-19 富士薬品工業株式会社 新規な抗ヒトトロンボモジュリンモノクローナル抗体によるヒトトロンボモジュリンおよびその分解産物の定量方法
JP3358819B2 (ja) * 1996-12-26 2002-12-24 第一ファインケミカル株式会社 尿検体処理剤
AU2227201A (en) * 1999-12-28 2001-07-09 Fuji Chemical Industries, Ltd. Method of judging the possibility of abortion/premature birth and reagent therefor
AU2007305550B2 (en) 2006-10-06 2010-09-30 Asahi Kasei Pharma Corporation Agent for Therapy and/or Improvement of Disseminated Intravascular Coagulation
WO2013073545A1 (ja) 2011-11-15 2013-05-23 旭化成ファーマ株式会社 敗血症の治療及び／又は改善のための医薬
CN104394885B (zh) 2012-05-31 2017-06-30 学校法人近畿大学 抗癌剂所致的末梢神经障碍性疼痛的预防和/或治疗剂
WO2020067389A1 (ja) 2018-09-28 2020-04-02 旭化成ファーマ株式会社 抗悪性腫瘍剤による末梢神経障害の症状軽減及び／又は発症抑制のための医薬
MX2021004511A (es) 2018-10-22 2021-06-08 Asahi Kasei Pharma Corp Medicamento para el tratamiento y/o mejora de la septicemia asociada con la anomalia de la coagulacion.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987000050A1 (fr) * 1985-06-28 1987-01-15 Asahi Kasei Kogyo Kabushiki Kaisha Nouvelle substance physiologiquement active limitant la coagulation du sang
ATE113062T1 (de) * 1986-07-15 1994-11-15 Kowa Co Throminbindende substanz und verfahren zu ihrer herstellung.

Also Published As

Publication number Publication date
JPH0542920B2 (enExample) 1993-06-30
JPS6447391A (en) 1989-02-21
EP0285511A3 (en) 1988-12-28
DE3876124D1 (en) 1993-01-07
EP0285511A2 (en) 1988-10-05
EP0285511B1 (en) 1992-11-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee