BRPI0720158A2 - Agentes para terapia e/ou melhora de coagulação intravascular disseminada, para reduzir a probabilidade de morte em pacientes sofrendo da mesma, métodos para selecionar pacientes, e, para tratar e/ou melhorar coagulação intravascular disseminada - Google Patents
Agentes para terapia e/ou melhora de coagulação intravascular disseminada, para reduzir a probabilidade de morte em pacientes sofrendo da mesma, métodos para selecionar pacientes, e, para tratar e/ou melhorar coagulação intravascular disseminadaInfo
- Publication number
- BRPI0720158A2 BRPI0720158A2 BRPI0720158-3A2A BRPI0720158A BRPI0720158A2 BR PI0720158 A2 BRPI0720158 A2 BR PI0720158A2 BR PI0720158 A BRPI0720158 A BR PI0720158A BR PI0720158 A2 BRPI0720158 A2 BR PI0720158A2
- Authority
- BR
- Brazil
- Prior art keywords
- intravascular coagulation
- patients
- death
- probability
- treat
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/7455—Thrombomodulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006274573 | 2006-10-06 | ||
PCT/JP2007/069560 WO2008044631A1 (fr) | 2006-10-06 | 2007-10-05 | Agent thérapeutique et/ou améliorant pour la coagulation intravasculaire disséminée |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0720158A2 true BRPI0720158A2 (pt) | 2014-05-20 |
Family
ID=39282827
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0720158-3A2A BRPI0720158A2 (pt) | 2006-10-06 | 2007-10-05 | Agentes para terapia e/ou melhora de coagulação intravascular disseminada, para reduzir a probabilidade de morte em pacientes sofrendo da mesma, métodos para selecionar pacientes, e, para tratar e/ou melhorar coagulação intravascular disseminada |
Country Status (17)
Country | Link |
---|---|
US (1) | US20100152106A1 (pt) |
EP (1) | EP2062589A4 (pt) |
JP (1) | JP5579385B2 (pt) |
KR (1) | KR20090051777A (pt) |
CN (1) | CN101522206B (pt) |
AU (1) | AU2007305550B2 (pt) |
BR (1) | BRPI0720158A2 (pt) |
CA (1) | CA2665691A1 (pt) |
CO (1) | CO6160332A2 (pt) |
HK (1) | HK1130209A1 (pt) |
IL (1) | IL197509A (pt) |
MX (1) | MX2009003384A (pt) |
MY (1) | MY148565A (pt) |
NZ (1) | NZ575632A (pt) |
RU (1) | RU2433829C2 (pt) |
UA (1) | UA97961C2 (pt) |
WO (1) | WO2008044631A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2009314413A1 (en) * | 2008-11-12 | 2010-05-20 | Eli Lilly And Company | Compositions and methods of use for soluble thrombomodulin variants |
MX2021003288A (es) * | 2018-09-28 | 2021-05-13 | Asahi Kasei Pharma Corp | Medicacion para aliviar los sintomas de la neuropatia periferica causada por farmacos anticancerigenos y/o suprimir el inicio de la neuropatia periferica. |
KR20210060574A (ko) * | 2018-10-22 | 2021-05-26 | 아사히 가세이 파마 가부시키가이샤 | 응고 이상을 수반하는 패혈증의 치료 및/또는 개선을 위한 의약 |
RU2716492C1 (ru) * | 2019-05-14 | 2020-03-12 | Федеральное Государственное Бюджетное Научное Учреждение "Федеральный Научно-Клинический Центр Реаниматологии И Реабилитологии" (Фнкц Рр) | Способ регулирования активации нейтрофилов в модели in vitro |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3856335T2 (de) * | 1987-01-08 | 2000-01-27 | Asahi Chemical Ind | Peptid zur beschleunigung der wirkung des proteins-c mit thrombin |
EP0285511B1 (en) | 1987-04-01 | 1992-11-25 | Mitsubishi Gas Chemical Company, Inc. | Immunoassay of thrombomodulin |
DK299087D0 (da) | 1987-06-12 | 1987-06-12 | Novo Industri As | Proteins and derivatives thereof |
JPS646219U (pt) | 1987-06-30 | 1989-01-13 | ||
JPS6445398U (pt) | 1987-09-11 | 1989-03-20 | ||
JPH0720997B2 (ja) * | 1988-08-29 | 1995-03-08 | 興和株式会社 | 新規なトロンビン結合性物質及びその製法 |
JPH0798840B2 (ja) | 1988-12-27 | 1995-10-25 | 持田製薬株式会社 | 尿由来の抗血液疑固物質、その製法およびそれを含有する医薬組成物 |
US5202421A (en) * | 1988-12-27 | 1993-04-13 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant substance obtained from urine and process for the preparation thereof |
JPH02255699A (ja) | 1989-03-28 | 1990-10-16 | Asahi Chem Ind Co Ltd | 新規血液抗凝固物質及びその製法 |
US6063763A (en) * | 1989-04-28 | 2000-05-16 | Schering Aktiengesellschaft | Protease-resistant thrombomodulin analogs |
CA2022713A1 (en) | 1989-08-11 | 1991-02-12 | Nils U. Bang | Human thrombomodulin derivatives |
JPH03259084A (ja) | 1990-03-06 | 1991-11-19 | Kowa Co | トロンビン結合性物質の製造法 |
AU643306B2 (en) * | 1990-06-27 | 1993-11-11 | Mochida Pharmaceutical Co., Ltd. | Anticoagulant polypeptides |
JPH05213998A (ja) | 1990-08-03 | 1993-08-24 | Asahi Chem Ind Co Ltd | 新規なポリペプチド及びこれを有効成分とする 医薬組成物 |
KR930008093B1 (ko) * | 1990-08-03 | 1993-08-25 | 아사히가세이고오교 가부시끼가이샤 | 신규 폴리펩티드 및 이를 유효성분으로 하는 의약조성물 |
AU8723391A (en) | 1990-08-15 | 1992-03-17 | Schering Aktiengesellschaft | Superior thrombomodulin analogs for pharmaceutical use |
JP3220174B2 (ja) | 1990-12-12 | 2001-10-22 | 第一製薬株式会社 | 組換ヒトトロンボモジュリン誘導体 |
ATE264913T1 (de) | 1992-02-05 | 2004-05-15 | Paion Gmbh | Protease-resistente analoge des thrombomodulin |
JPH05310787A (ja) | 1992-05-01 | 1993-11-22 | Asahi Chem Ind Co Ltd | 新規なポリペプチド |
JPH06205692A (ja) | 1993-01-08 | 1994-07-26 | Asahi Chem Ind Co Ltd | 新規な抗ヒトトロンボモジュリンモノクロ−ナル抗体およびその抗体を用いたヒトトロンボモジュリンの高感度測定方法 |
US5916874A (en) * | 1994-04-20 | 1999-06-29 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for treating liver injury |
JP2824392B2 (ja) | 1994-05-31 | 1998-11-11 | 旭化成工業株式会社 | トロンビンによるプロテインcの活性化を促進する作用を有するペプチドを含有する培養上澄液 |
JP3745805B2 (ja) | 1995-10-24 | 2006-02-15 | 日本ケミカルリサーチ株式会社 | トロンボモジュリンの精製方法 |
JP4157644B2 (ja) | 1998-03-30 | 2008-10-01 | 旭化成ファーマ株式会社 | 高純度可溶性トロンボモジュリンの製造方法 |
AU2003213598A1 (en) * | 2002-02-27 | 2003-09-09 | Biomerieux, Inc. | Method for diagnosing and monitoring hemostatic dysfunction, severe infection and systematic inflammatory response syndrome |
MXPA04010851A (es) * | 2002-05-01 | 2005-02-14 | Schering Ag | Proteinas de fusion de trombomodulina dirigidas al factor tisular novedoso como anticoagulantes. |
-
2007
- 2007-10-05 CN CN2007800368187A patent/CN101522206B/zh active Active
- 2007-10-05 AU AU2007305550A patent/AU2007305550B2/en active Active
- 2007-10-05 MX MX2009003384A patent/MX2009003384A/es active IP Right Grant
- 2007-10-05 WO PCT/JP2007/069560 patent/WO2008044631A1/ja active Application Filing
- 2007-10-05 RU RU2009117253/15A patent/RU2433829C2/ru active
- 2007-10-05 KR KR1020097006989A patent/KR20090051777A/ko active Search and Examination
- 2007-10-05 EP EP07829298A patent/EP2062589A4/en not_active Withdrawn
- 2007-10-05 NZ NZ575632A patent/NZ575632A/en unknown
- 2007-10-05 MY MYPI20091065A patent/MY148565A/en unknown
- 2007-10-05 UA UAA200904468A patent/UA97961C2/ru unknown
- 2007-10-05 JP JP2008538700A patent/JP5579385B2/ja active Active
- 2007-10-05 US US12/444,342 patent/US20100152106A1/en not_active Abandoned
- 2007-10-05 BR BRPI0720158-3A2A patent/BRPI0720158A2/pt not_active Application Discontinuation
- 2007-10-05 CA CA002665691A patent/CA2665691A1/en not_active Abandoned
-
2009
- 2009-03-10 IL IL197509A patent/IL197509A/en active IP Right Grant
- 2009-03-20 CO CO09029277A patent/CO6160332A2/es unknown
- 2009-11-05 HK HK09110256.9A patent/HK1130209A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL197509A (en) | 2015-06-30 |
UA97961C2 (ru) | 2012-04-10 |
NZ575632A (en) | 2011-12-22 |
AU2007305550B2 (en) | 2010-09-30 |
JP5579385B2 (ja) | 2014-08-27 |
RU2009117253A (ru) | 2010-11-20 |
MY148565A (en) | 2013-04-30 |
AU2007305550A1 (en) | 2008-04-17 |
IL197509A0 (en) | 2011-08-01 |
HK1130209A1 (en) | 2009-12-24 |
RU2433829C2 (ru) | 2011-11-20 |
CN101522206A (zh) | 2009-09-02 |
KR20090051777A (ko) | 2009-05-22 |
CN101522206B (zh) | 2013-03-27 |
MX2009003384A (es) | 2009-04-08 |
CA2665691A1 (en) | 2008-04-17 |
EP2062589A4 (en) | 2010-07-28 |
US20100152106A1 (en) | 2010-06-17 |
EP2062589A1 (en) | 2009-05-27 |
WO2008044631A1 (fr) | 2008-04-17 |
JPWO2008044631A1 (ja) | 2010-02-12 |
CO6160332A2 (es) | 2010-05-20 |
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BRPI0720158A2 (pt) | Agentes para terapia e/ou melhora de coagulação intravascular disseminada, para reduzir a probabilidade de morte em pacientes sofrendo da mesma, métodos para selecionar pacientes, e, para tratar e/ou melhorar coagulação intravascular disseminada |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
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