DE3788352T2 - Verfahren zur herstellung eines heterologen proteins in insektenzellen. - Google Patents

Verfahren zur herstellung eines heterologen proteins in insektenzellen.

Info

Publication number
DE3788352T2
DE3788352T2 DE87906361T DE3788352T DE3788352T2 DE 3788352 T2 DE3788352 T2 DE 3788352T2 DE 87906361 T DE87906361 T DE 87906361T DE 3788352 T DE3788352 T DE 3788352T DE 3788352 T2 DE3788352 T2 DE 3788352T2
Authority
DE
Germany
Prior art keywords
producing
insect cells
heterological
protein
heterological protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE87906361T
Other languages
English (en)
Other versions
DE3788352D1 (de
Inventor
David Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC
Application granted granted Critical
Publication of DE3788352D1 publication Critical patent/DE3788352D1/de
Publication of DE3788352T2 publication Critical patent/DE3788352T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/14011—Baculoviridae
    • C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE87906361T 1986-09-09 1987-09-09 Verfahren zur herstellung eines heterologen proteins in insektenzellen. Expired - Fee Related DE3788352T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90572986A 1986-09-09 1986-09-09
PCT/US1987/002315 WO1988002030A1 (en) 1986-09-09 1987-09-09 Method for producing a heterologous protein in insect cells

Publications (2)

Publication Number Publication Date
DE3788352D1 DE3788352D1 (de) 1994-01-13
DE3788352T2 true DE3788352T2 (de) 1994-03-17

Family

ID=25421367

Family Applications (1)

Application Number Title Priority Date Filing Date
DE87906361T Expired - Fee Related DE3788352T2 (de) 1986-09-09 1987-09-09 Verfahren zur herstellung eines heterologen proteins in insektenzellen.

Country Status (8)

Country Link
EP (1) EP0323974B1 (de)
JP (1) JPH02500402A (de)
AU (1) AU601232B2 (de)
CA (1) CA1330426C (de)
DE (1) DE3788352T2 (de)
ES (1) ES2008204A6 (de)
WO (1) WO1988002030A1 (de)
ZA (1) ZA876696B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8810808D0 (en) * 1988-05-06 1988-06-08 Wellcome Found Vectors
JP2511494B2 (ja) * 1988-05-12 1996-06-26 善治 松浦 日本脳炎ウイルス表面抗原蛋白質の製造法
AU4197389A (en) * 1988-08-05 1990-03-05 Mount Sinai School Of Medicine Of The City University Of New York, The In vivo infection of live insects with a recombinant baculovirus
AU4647889A (en) * 1988-11-18 1990-06-12 Cetus Corporation Insect signal peptide mediated secretion of recombinant proteins
US5272063A (en) * 1988-11-22 1993-12-21 Syntex (U.S.A.) Inc. Process of making human nerve growth factor
US5145775A (en) * 1989-02-28 1992-09-08 Research Association For Biotechnology Of Agricultural Chemicals Polyhedrin gene and genetic engineering thereof
GB9219562D0 (en) 1992-03-11 1992-10-28 Prendergast Kennet F Anti-viral peptides
HU218849B (hu) * 1992-06-01 2000-12-28 American Cyanamid Co. Gazdaszervezetről gazdaszervezetre a környezetben csökkent terjedési képességgel rendelkező rekombináns bakulovirus és eljárás előállítására
US6130074A (en) * 1992-06-01 2000-10-10 American Cyanamid Company Five Giralda Farms Recombinant insect virus with reduced capacity for host-to-host transmission in the environment and methods to produce said virus
DE69632658T2 (de) * 1995-03-14 2005-06-09 Akzo Nobel N.V. Expression in der selben Zelle von Polypeptide vom schweinen reproduktiven und respiratorischen Syndrom
TR201814974T4 (tr) 2013-09-23 2018-10-22 Association Pour La Rech Et Le Developpement Des Methodes Et Processus Industriels Armines Zararlı böceklerle mücadele edilmesi için kullanılabilen farklı bakulovirüs türlerinin genomlarını içeren viryonları tıkayan virüs oklüzyon korlarının üretimi.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA848495B (en) * 1984-01-31 1985-09-25 Idaho Res Found Production of polypeptides in insect cells
EP0222412B1 (de) * 1985-11-14 1992-11-19 Daiichi Pharmaceutical Co., Ltd. Verfahren zur Herstellung von Peptiden
EP0260090A3 (de) * 1986-09-08 1988-07-27 David H.L. Bishop Expression von Hepatitis B-Virusantigenen von rekombinanten Bakulovirusvektoren

Also Published As

Publication number Publication date
DE3788352D1 (de) 1994-01-13
JPH02500402A (ja) 1990-02-15
WO1988002030A1 (en) 1988-03-24
ES2008204A6 (es) 1989-07-16
AU601232B2 (en) 1990-09-06
ZA876696B (en) 1988-05-25
EP0323974A1 (de) 1989-07-19
AU8032387A (en) 1988-04-07
CA1330426C (en) 1994-06-28
EP0323974A4 (de) 1990-02-21
EP0323974B1 (de) 1993-12-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee