DE3687543T2 - Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter. - Google Patents

Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter.

Info

Publication number
DE3687543T2
DE3687543T2 DE8686302650T DE3687543T DE3687543T2 DE 3687543 T2 DE3687543 T2 DE 3687543T2 DE 8686302650 T DE8686302650 T DE 8686302650T DE 3687543 T DE3687543 T DE 3687543T DE 3687543 T2 DE3687543 T2 DE 3687543T2
Authority
DE
Germany
Prior art keywords
waveguide
medium
wave guide
measuring probe
biological molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686302650T
Other languages
English (en)
Other versions
DE3687543D1 (de
Inventor
William James Stewart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Marconi UK Intellectual Property Ltd
Original Assignee
GEC Marconi Ltd
Marconi Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GEC Marconi Ltd, Marconi Co Ltd filed Critical GEC Marconi Ltd
Application granted granted Critical
Publication of DE3687543D1 publication Critical patent/DE3687543D1/de
Publication of DE3687543T2 publication Critical patent/DE3687543T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
DE8686302650T 1985-04-12 1986-04-10 Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter. Expired - Fee Related DE3687543T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858509491A GB8509491D0 (en) 1985-04-12 1985-04-12 Optic waveguide biosensors

Publications (2)

Publication Number Publication Date
DE3687543D1 DE3687543D1 (de) 1993-03-04
DE3687543T2 true DE3687543T2 (de) 1993-05-13

Family

ID=10577584

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686302650T Expired - Fee Related DE3687543T2 (de) 1985-04-12 1986-04-10 Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter.

Country Status (6)

Country Link
US (1) US4857273A (de)
EP (1) EP0205236B1 (de)
JP (1) JPH07117486B2 (de)
AT (1) ATE84876T1 (de)
DE (1) DE3687543T2 (de)
GB (2) GB8509491D0 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004045902A1 (de) * 2004-09-22 2006-03-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. ATR-Sensorelement

Families Citing this family (129)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3001669A1 (de) * 1980-01-18 1981-08-06 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Anordnung zur optischen messung von physikalischen groessen und stoffkonzentrationen
DE3680999D1 (de) * 1985-05-29 1991-09-26 Artificial Sensing Instr Asi A Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahlaenderungen in messubstanzen.
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
AU615928B2 (en) * 1987-06-20 1991-10-17 Applied Research Systems Ars Holding N.V. Waveguide sensor
GB8714503D0 (en) * 1987-06-20 1987-07-22 Pa Consulting Services Detector
JPS646842A (en) * 1987-06-30 1989-01-11 Ricoh Kk Detecting device
GB8801807D0 (en) * 1988-01-27 1988-02-24 Amersham Int Plc Biological sensors
DE68907519T2 (de) * 1988-05-10 1993-10-21 Amersham Int Plc Biosensoren.
GB8811919D0 (en) * 1988-05-20 1988-06-22 Amersham Int Plc Biological sensors
GB8813307D0 (en) * 1988-06-06 1988-07-13 Amersham Int Plc Biological sensors
GB8817710D0 (en) * 1988-07-25 1988-09-01 Ares Serono Res & Dev Ltd Method of assay
SE462454B (sv) * 1988-11-10 1990-06-25 Pharmacia Ab Maetyta foer anvaendning i biosensorer
GB8827853D0 (en) * 1988-11-29 1988-12-29 Ares Serono Res & Dev Ltd Sensor for optical assay
GB2227089A (en) * 1989-01-11 1990-07-18 Plessey Co Plc An optical biosensor
GB2228082A (en) * 1989-01-13 1990-08-15 Marconi Gec Ltd Gas or liquid chemical sensor
US5401469A (en) * 1989-04-19 1995-03-28 Ibiden Co., Ltd. Plastic optical biomaterials assay device
US6010867A (en) * 1989-04-19 2000-01-04 Ibiden Co., Ltd. Reagent for biomaterials assay, preparation method thereof, and assay method
WO1990013029A1 (en) * 1989-04-19 1990-11-01 Ibiden Co., Ltd. Reagent for assaying biologically active substance, method of production thereof, and method and apparatus for assaying
US5491097A (en) * 1989-06-15 1996-02-13 Biocircuits Corporation Analyte detection with multilayered bioelectronic conductivity sensors
US5156810A (en) * 1989-06-15 1992-10-20 Biocircuits Corporation Biosensors employing electrical, optical and mechanical signals
DE3923921A1 (de) * 1989-07-19 1991-01-24 Biotechnolog Forschung Gmbh Optischer biosensor
DE4033741C2 (de) * 1989-11-02 1994-03-31 Falko Volkhardt E Dipl Tittel Vorrichtung zum Nachweis von HIV-Antikörpern im Vollblut mit Anzeige des Ergebnisses
GB8924951D0 (en) * 1989-11-04 1989-12-28 Fisons Plc Device and methods
US5075551A (en) * 1990-03-12 1991-12-24 Fuji Electric Co., Ltd. Infrared absorption enhanced spectroscopic apparatus
US5143066A (en) * 1990-05-08 1992-09-01 University Of Pittsburgh Optical fiber sensors for continuous monitoring of biochemicals and related method
EP0543831B1 (de) * 1990-08-17 1995-12-13 FISONS plc Vorrichtung zur analyse
GB9018195D0 (en) * 1990-08-18 1990-10-03 Fisons Plc Analytical device
GB2248497B (en) * 1990-09-26 1994-05-25 Marconi Gec Ltd An optical sensor
US5192510A (en) * 1991-01-30 1993-03-09 E. I. Du Pont De Nemours And Company Apparatus for performing fluorescent assays which separates bulk and evanescent fluorescence
EP0573572B1 (de) * 1991-02-27 1998-01-21 Boehringer Mannheim Corporation Verbesserter teststreifen
US5271895A (en) * 1991-02-27 1993-12-21 Boehringer Mannheim Corporation Test strip
EP0587568A1 (de) * 1991-03-09 1994-03-23 FISONS plc Analytische Verfahren und Vorrichtungen
GB2254415B (en) * 1991-03-22 1994-10-12 Marconi Gec Ltd An optical sensor
GB9111912D0 (en) * 1991-06-04 1991-07-24 Fisons Plc Analytical methods
GB2256477B (en) * 1991-06-07 1995-03-08 Marconi Gec Ltd An optical sensor
GB9120000D0 (en) * 1991-09-19 1991-11-06 British Gas Plc Optical sensing
US5354574A (en) * 1992-06-23 1994-10-11 Ibiden Co., Ltd. Method for producing optical fiber having formyl groups on core surface thereof
US6256522B1 (en) 1992-11-23 2001-07-03 University Of Pittsburgh Of The Commonwealth System Of Higher Education Sensors for continuous monitoring of biochemicals and related method
DE4411035A1 (de) * 1993-04-23 1994-11-03 Fraunhofer Ges Forschung Optischer Sensor
US5512492A (en) * 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
JPH09505135A (ja) * 1993-05-28 1997-05-20 ファイソンズ ピーエルシー 分析装置
US5538850A (en) * 1994-04-15 1996-07-23 Hewlett-Packard Company Apparatus and method for intracavity sensing of microscopic properties of chemicals
US5437840A (en) * 1994-04-15 1995-08-01 Hewlett-Packard Company Apparatus for intracavity sensing of macroscopic properties of chemicals
JPH07318481A (ja) * 1994-05-25 1995-12-08 Daikin Ind Ltd 光学的測定方法およびその装置
US6287850B1 (en) * 1995-06-07 2001-09-11 Affymetrix, Inc. Bioarray chip reaction apparatus and its manufacture
JPH08116961A (ja) * 1994-10-25 1996-05-14 Hamamatsu Photonics Kk 培養観測用容器及び観測装置
US5814565A (en) * 1995-02-23 1998-09-29 University Of Utah Research Foundation Integrated optic waveguide immunosensor
US5633724A (en) * 1995-08-29 1997-05-27 Hewlett-Packard Company Evanescent scanning of biochemical array
US5991048A (en) * 1995-10-25 1999-11-23 University Of Washington Surface plasmon resonance light pipe sensor
US6660233B1 (en) 1996-01-16 2003-12-09 Beckman Coulter, Inc. Analytical biochemistry system with robotically carried bioarray
US5854863A (en) * 1996-03-15 1998-12-29 Erb; Judith Surface treatment and light injection method and apparatus
JP3886153B2 (ja) * 1996-03-19 2007-02-28 ユニバーシティー オブ ユタ リサーチ ファンデーション レンズおよび連結可能なフローセル
US5832165A (en) * 1996-08-28 1998-11-03 University Of Utah Research Foundation Composite waveguide for solid phase binding assays
GB9618635D0 (en) * 1996-09-06 1996-10-16 Thermo Fast Uk Ltd Improvements in or relating to sensors
EP0834735A3 (de) * 1996-10-01 1999-08-11 Texas Instruments Inc. Sensor
US5922537A (en) * 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
JPH10221249A (ja) * 1996-12-05 1998-08-21 Norio Miura 薬物の測定装置とセンサ及び該センサに用いる検出素子
US6025189A (en) * 1997-05-14 2000-02-15 3M Innovative Properties Company Apparatus for reading a plurality of biological indicators
WO1998059234A1 (en) 1997-06-24 1998-12-30 The University Of Wyoming Method and apparatus for detection of a controlled substance
US6222619B1 (en) 1997-09-18 2001-04-24 University Of Utah Research Foundation Diagnostic device and method
US6100541A (en) 1998-02-24 2000-08-08 Caliper Technologies Corporation Microfluidic devices and systems incorporating integrated optical elements
US6429023B1 (en) 1998-07-20 2002-08-06 Shayda Technologies, Inc. Biosensors with polymeric optical waveguides
US6573107B1 (en) 1998-08-05 2003-06-03 The University Of Wyoming Immunochemical detection of an explosive substance in the gas phase through surface plasmon resonance spectroscopy
US6770488B1 (en) 1999-03-19 2004-08-03 The University Of Wyoming Practical method and apparatus for analyte detection with colloidal particles
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US6315958B1 (en) * 1999-11-10 2001-11-13 Wisconsin Alumni Research Foundation Flow cell for synthesis of arrays of DNA probes and the like
US6458326B1 (en) 1999-11-24 2002-10-01 Home Diagnostics, Inc. Protective test strip platform
US20080220440A1 (en) * 2000-07-25 2008-09-11 M Selim Unlu Waveguide sensors optimized for discrimination against non-specific binding
US7384797B1 (en) * 2000-10-12 2008-06-10 University Of Utah Research Foundation Resonant optical cavities for high-sensitivity high-throughput biological sensors and methods
US7205347B2 (en) * 2000-10-19 2007-04-17 Trans Photonics, Llc. Substituted-polyaryl chromophoric compounds
US7575939B2 (en) * 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7217574B2 (en) * 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7023544B2 (en) * 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7306827B2 (en) * 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US7153702B2 (en) * 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7070987B2 (en) * 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7101660B2 (en) * 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7175980B2 (en) * 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US20030113766A1 (en) * 2000-10-30 2003-06-19 Sru Biosystems, Llc Amine activated colorimetric resonant biosensor
US6951715B2 (en) * 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7300803B2 (en) * 2000-10-30 2007-11-27 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7202076B2 (en) * 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7875434B2 (en) * 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7264973B2 (en) * 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US7094595B2 (en) * 2000-10-30 2006-08-22 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7142296B2 (en) * 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US20030092075A1 (en) * 2000-10-30 2003-05-15 Sru Biosystems, Llc Aldehyde chemical surface activation processes and test methods for colorimetric resonant sensors
US7615339B2 (en) * 2000-10-30 2009-11-10 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
US6562625B2 (en) 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
WO2003036225A1 (en) * 2001-10-26 2003-05-01 University Of Rochester Method for biomolecular sensing and system thereof
US6707958B2 (en) * 2001-11-20 2004-03-16 Agilent Technologies, Inc. Biochemical assay device using frustrated total internal reflection modulator with an imaging optical waveguide
AU2003210523B2 (en) * 2002-01-28 2008-03-20 Sru Biosystems, Inc. A guided mode resonant filter biosensor using a linear grating surface structure
US7018842B2 (en) * 2002-02-28 2006-03-28 Agilent Technologies, Inc. Reading dry chemical arrays through the substrate
US7154598B2 (en) * 2002-07-12 2006-12-26 Decision Biomarkers, Inc. Excitation and imaging of fluorescent arrays
US7384742B2 (en) * 2002-08-16 2008-06-10 Decision Biomarkers, Inc. Substrates for isolating reacting and microscopically analyzing materials
US20060127946A1 (en) * 2002-08-16 2006-06-15 Montagu Jean I Reading of fluorescent arrays
US7429492B2 (en) * 2002-09-09 2008-09-30 Sru Biosystems, Inc. Multiwell plates with integrated biosensors and membranes
US7927822B2 (en) * 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US7309614B1 (en) 2002-12-04 2007-12-18 Sru Biosystems, Inc. Self-referencing biodetection method and patterned bioassays
WO2004083820A2 (en) * 2003-03-19 2004-09-30 Trustees Of Boston University Resonant cavity biosensor
US8298780B2 (en) * 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
AU2004290375A1 (en) * 2003-11-06 2005-05-26 Sru Biosystems, Inc. High-density amine-functionalized surface
GB0405823D0 (en) * 2004-03-15 2004-04-21 Evanesco Ltd Functionalised surface sensing apparatus and methods
US7709247B2 (en) * 2004-08-04 2010-05-04 Intel Corporation Methods and systems for detecting biomolecular binding using terahertz radiation
US7551294B2 (en) * 2005-09-16 2009-06-23 University Of Rochester System and method for brewster angle straddle interferometry
DE102005062174C5 (de) * 2005-12-23 2010-05-06 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Meßchip
US8062595B2 (en) * 2006-02-06 2011-11-22 Stmicroelectronics S.R.L. Nucleic acid analysis chip integrating a waveguide and optical apparatus for the inspection of nucleic acid probes
US20070235397A1 (en) * 2006-03-30 2007-10-11 Wannop George M Storage bin and frame system
US7692798B2 (en) * 2006-09-15 2010-04-06 Adarza Biosystems, Inc. Method for biomolecular detection and system thereof
WO2008072156A2 (en) 2006-12-12 2008-06-19 Koninklijke Philips Electronics N. V. Microelectronic sensor device for detecting label particles
JP2010525334A (ja) * 2007-04-19 2010-07-22 エス アール ユー バイオシステムズ，インコーポレイテッド 固定化された標的と直接結合する小分子を検出するためにバイオセンサーを使用する方法
DE102007025513B4 (de) * 2007-06-01 2014-06-05 Hahn-Schickard-Gesellschaft für angewandte Forschung e.V. Vorrichtung und Verfahren zum Ermöglichen der Bewertung eines Füllzustands
JP2010532998A (ja) 2007-07-11 2010-10-21 エス アール ユー バイオシステムズ，インコーポレイテッド イオンチャネルのモジュレータを識別する方法
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
WO2009149285A1 (en) * 2008-06-04 2009-12-10 Sru Biosystems, Inc. Detection of promiscuous small submicrometer aggregates
EP2331934B1 (de) * 2008-09-16 2020-01-01 Pacific Biosciences of California, Inc. Analysegerät mit Nullmoden-Wellenleiter Substrat
JP2012526998A (ja) * 2009-05-15 2012-11-01 エス アール ユー バイオシステムズ，インコーポレイテッド 細胞集団および混合細胞集団における変化の検出
US8694069B1 (en) 2009-12-21 2014-04-08 Kosense, LLC Fiber-optic probe with embedded peripheral sensors for in-situ continuous monitoring
US8750652B2 (en) * 2010-10-12 2014-06-10 The Board Of Trustees Of The Leland Stanford Junior University Microfluidic waveguide detector
FR2970079B1 (fr) * 2010-12-29 2022-08-12 Genewave Dispositif de type biopuce
US20130201316A1 (en) 2012-01-09 2013-08-08 May Patents Ltd. System and method for server based control
DE102017211910A1 (de) * 2017-07-12 2019-01-17 Dr. Johannes Heidenhain Gmbh Diffraktiver Biosensor
WO2019043446A1 (en) 2017-09-04 2019-03-07 Nng Software Developing And Commercial Llc METHOD AND APPARATUS FOR COLLECTING AND USING SENSOR DATA FROM A VEHICLE
EP3801746B1 (de) 2018-08-14 2023-05-10 Neurotrigger Ltd. Vorrichtung zur transkutanen gesichtsnervenstimulation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE364371B (de) * 1969-01-24 1974-02-18 Western Electric Co
FR2193990B1 (de) * 1972-07-25 1976-01-16 Thomson Csf Fr
US3883221A (en) * 1974-02-01 1975-05-13 Bell Telephone Labor Inc Portable prism-grating coupler
US4059338A (en) * 1975-09-09 1977-11-22 Sharp Kabushiki Kaisha Integrated optical waveguide coupler
JPS5821213A (ja) * 1981-07-31 1983-02-08 Canon Inc 光結合装置
EP0075353B1 (de) * 1981-09-18 1987-08-19 Battelle Memorial Institute Verfahren und Vorrichtung zur Bestimmung von gelösten Stoffen mit Hilfe eines optischen Wellenleiters
US4582809A (en) * 1982-06-14 1986-04-15 Myron J. Block Apparatus including optical fiber for fluorescence immunoassay
US4447546A (en) * 1982-08-23 1984-05-08 Myron J. Block Fluorescent immunoassay employing optical fiber in capillary tube
GB2146788B (en) * 1983-09-20 1986-09-24 Stc Plc Prism coupling to flat waveguides
US4565422A (en) * 1983-11-30 1986-01-21 Gte Laboratories Incorporated Surface plasmon coupler
GB2156970B (en) * 1984-01-06 1987-09-16 Plessey Co Plc Optical detection of specific molecules

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004045902A1 (de) * 2004-09-22 2006-03-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. ATR-Sensorelement
DE102004045902B4 (de) * 2004-09-22 2006-08-31 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur Messung der Lichtabsorption

Also Published As

Publication number Publication date
ATE84876T1 (de) 1993-02-15
GB8608448D0 (en) 1986-05-14
JPS61292044A (ja) 1986-12-22
US4857273A (en) 1989-08-15
EP0205236A3 (en) 1989-05-24
GB2174802A (en) 1986-11-12
EP0205236B1 (de) 1993-01-20
DE3687543D1 (de) 1993-03-04
GB8509491D0 (en) 1985-05-15
JPH07117486B2 (ja) 1995-12-18
EP0205236A2 (de) 1986-12-17
GB2174802B (en) 1989-08-02

Similar Documents

Publication Publication Date Title
DE3687543T2 (de) Messfuehler fuer biologische molekuele mit verwendung optischer wellenleiter.
Slavı́k et al. Miniaturization of fiber optic surface plasmon resonance sensor
US4877747A (en) Optical assay: method and apparatus
US6021240A (en) Optical sensor activation device
Lavers et al. A waveguide-coupled surface-plasmon sensor for an aqueous environment
US6343168B1 (en) Optical sensor arrangement
ATE110857T1 (de) Optisches element.
NO894745L (no) Boelgeleder-sensor.
DE68903688D1 (de) Biosensoren.
AU2884289A (en) Biological sensors
ATE116060T1 (de) Sensor für den brechungsindex aus optischen fasern unter verwendung einer metallbeschichtung.
US5245410A (en) Optical fiber sensor based on the excitation of surface plasmon
JP2650998B2 (ja) 液体、気体等の検知用光ファイバ
Thompson et al. Waveguide parameter for waveguide-binding fiber optic biosensors
Nath et al. Fiber optic refractometers: A brief qualitative review
Homola et al. Surface plasmon resonance sensors using optical waveguides
JPH01295137A (ja) 屈折率測定センサ
JP2794829B2 (ja) 光ファイバ屈折計
JPS60152914U (ja) 光導波形センサ
JPH01321342A (ja) 気体検出装置
Schuster et al. A Fiber-Optic Surface-Plasmon-Resonance Bio-Sensor
JPS6438634A (en) Sensor head for refractometer
JPS55118001A (en) Optical divider
JPS6454230A (en) Optical fiber for liquid detection and liquid detection system using the same
KR880006558A (ko) 광 결합기

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: PATENTANWAELTE REICHEL UND REICHEL, 60322 FRANKFURT

8327 Change in the person/name/address of the patent owner

Owner name: MARCONI CASWELL LTD., LONDON, GB

8327 Change in the person/name/address of the patent owner

Owner name: MARCONI UK INTELLECTUAL PROPERTY LTD., COVENTRY, G

8339 Ceased/non-payment of the annual fee