DE3679204D1 - Verfahren zur herstellung kleiner vesikel durch mikroemulgierung. - Google Patents

Verfahren zur herstellung kleiner vesikel durch mikroemulgierung.

Info

Publication number
DE3679204D1
DE3679204D1 DE8686300641T DE3679204T DE3679204D1 DE 3679204 D1 DE3679204 D1 DE 3679204D1 DE 8686300641 T DE8686300641 T DE 8686300641T DE 3679204 T DE3679204 T DE 3679204T DE 3679204 D1 DE3679204 D1 DE 3679204D1
Authority
DE
Germany
Prior art keywords
microemulgation
vesicles
producing small
small vesicles
lipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8686300641T
Other languages
English (en)
Inventor
Ronald Carl Gamble
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nexstar Pharmaceuticals Inc
Original Assignee
Vestar Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vestar Inc filed Critical Vestar Inc
Application granted granted Critical
Publication of DE3679204D1 publication Critical patent/DE3679204D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/829—Liposomes, e.g. encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Colloid Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DE8686300641T 1985-01-31 1986-01-30 Verfahren zur herstellung kleiner vesikel durch mikroemulgierung. Expired - Lifetime DE3679204D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/696,727 US4753788A (en) 1985-01-31 1985-01-31 Method for preparing small vesicles using microemulsification

Publications (1)

Publication Number Publication Date
DE3679204D1 true DE3679204D1 (de) 1991-06-20

Family

ID=24798285

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686300641T Expired - Lifetime DE3679204D1 (de) 1985-01-31 1986-01-30 Verfahren zur herstellung kleiner vesikel durch mikroemulgierung.

Country Status (7)

Country Link
US (1) US4753788A (de)
EP (1) EP0190050B1 (de)
JP (1) JPH0776170B2 (de)
AT (1) ATE63456T1 (de)
CA (1) CA1282699C (de)
DE (1) DE3679204D1 (de)
IE (1) IE57225B1 (de)

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ES2041597B1 (es) * 1992-05-05 1994-06-01 Bazaco Joan Freixas Nuevo procedimiento para la preparacion de liposomas que encapsulan productos farmaceuticos y cosmeticos.
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US5759571A (en) * 1993-05-11 1998-06-02 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for drug resistant infections
DE69407292T2 (de) * 1993-06-30 1998-06-25 Genentech Inc Verfahren zur herstellung von liposomen
WO1995003035A1 (en) * 1993-07-23 1995-02-02 Massachusetts Institute Of Technology Polymerized liposomes with enhanced stability for oral delivery
US6004534A (en) * 1993-07-23 1999-12-21 Massachusetts Institute Of Technology Targeted polymerized liposomes for improved drug delivery
NZ275054A (en) * 1993-11-08 1997-04-24 Peptide Delivery Systems Pty L Diagnosing atherosclerosis or coronary artery disease using labelled composition which mimics essential features of an exogenous lipoprotein
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US5589189A (en) * 1994-09-14 1996-12-31 Nexstar Pharmaceuticals, Inc. Liposome dispersion
US5662929A (en) * 1994-12-23 1997-09-02 Universite De Montreal Therapeutic liposomal formulation
ATE452136T1 (de) 1995-05-04 2010-01-15 Gilead Sciences Inc Nukleinsäureligand-komplexe
DE19639811A1 (de) * 1996-09-27 1998-04-02 Artur Herzog Dr Mesmer Verwendung einer Liposomenlösung zur Verstärkung der Wirksamkeit und/oder Verminderung der Toxizität von Arzneimitteln
US6060082A (en) 1997-04-18 2000-05-09 Massachusetts Institute Of Technology Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
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US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
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US6171652B1 (en) * 1998-05-26 2001-01-09 Brij P. Singh Method for modifying surfaces with ultra thin films
US6613352B2 (en) 1999-04-13 2003-09-02 Universite De Montreal Low-rigidity liposomal formulation
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PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
US20030096864A1 (en) * 2000-06-30 2003-05-22 Fang Lawrence Y. Compounds to treat alzheimer's disease
US20020150566A1 (en) * 2001-03-23 2002-10-17 Kun-Liang Guan Method of inhibiting cancerous cell proliferation using Ras mutants of GDP-bound conformation
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
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US9944713B2 (en) 2004-11-24 2018-04-17 Medicinal Bioconvergence Research Center Antibody specific to the AIMP2-DX2
US7459529B2 (en) 2004-11-24 2008-12-02 Seoul National University Industry Foundation AIMP2-DX2 and its uses
US20080045575A1 (en) * 2004-12-29 2008-02-21 Van Dyke Thomas E Delivery of H2 Antagonists
EP2010117A4 (de) * 2006-04-12 2010-12-01 Massachusetts Inst Technology Zusammensetzungen und verfahren zur adhäsionshemmung
EP3115060A1 (de) 2008-04-18 2017-01-11 VaxInnate Corporation Flagellin deletionsmutanten und deren verwendung
US9226984B2 (en) * 2010-12-14 2016-01-05 Technical University of Denmark and Rigshospitalet Entrapment of radionuclides in nanoparticle compositions
WO2012138867A2 (en) 2011-04-07 2012-10-11 The Board Of Trustees Of The Leland Stanford Junior University Long-acting peptide analogs
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DK3615545T3 (da) 2017-04-24 2021-11-22 Cocrystal Pharma Inc Pyrrolopyrimidinderivativer, der er nyttige som hæmmere af replikation af influenzavirus
JP2021532149A (ja) 2018-07-27 2021-11-25 コクリスタル ファーマ, インコーポレイテッドCocrystal Pharma, Inc. インフルエンザウイルス複製阻害剤としてのピロロ［２，３−ｂ］ピリジン誘導体
ES2937837T3 (es) 2018-09-10 2023-03-31 Cocrystal Pharma Inc Inhibidores de piridopirazina y piridotriazina de la replicación del virus de la gripe
BR112021007275A2 (pt) 2018-10-17 2021-07-20 Cocrystal Pharma, Inc. combinações de inibidores de replicação de vírus da influenza
WO2020112716A1 (en) 2018-11-26 2020-06-04 Cocrystal Pharma, Inc. Inhibitors of influenza virus replication
WO2021188620A1 (en) 2020-03-17 2021-09-23 Cocrystal Pharma Inc. Peptidomimetic n5-methyl-n2-(nonanoyl-l-leucyl)-l-glutaminate derivatives, triazaspiro[4.14]nonadecane derivatives and similar compounds as inhibitors of norovirus and coronavirus replication
KR20230008079A (ko) 2020-04-10 2023-01-13 코크리스탈 파마, 아이엔씨. 노로바이러스 및 코로나바이러스 복제 억제제
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JPS5186117A (en) * 1975-01-27 1976-07-28 Tanabe Seiyaku Co Johoseibiryushiseizainoseiho
US4263428A (en) * 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
US4310506A (en) * 1979-02-22 1982-01-12 California Institute Of Technology Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species
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US4310505A (en) * 1979-11-08 1982-01-12 California Institute Of Technology Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances
US4485054A (en) * 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
FR2534487B1 (fr) * 1982-10-15 1988-06-10 Dior Christian Parfums Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede
US4544545A (en) * 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting

Also Published As

Publication number Publication date
JPH0776170B2 (ja) 1995-08-16
IE57225B1 (en) 1992-06-03
EP0190050A2 (de) 1986-08-06
US4753788A (en) 1988-06-28
JPS61218515A (ja) 1986-09-29
IE860273L (en) 1986-07-31
EP0190050B1 (de) 1991-05-15
ATE63456T1 (de) 1991-06-15
CA1282699C (en) 1991-04-09
EP0190050A3 (en) 1987-09-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NEXSTAR PHARMACEUTICALS INC. (N.D.GES.D. STAATES D