ATE330002T1 - Verfahren zur herstellung von membranvesikeln - Google Patents
Verfahren zur herstellung von membranvesikelnInfo
- Publication number
- ATE330002T1 ATE330002T1 AT01943246T AT01943246T ATE330002T1 AT E330002 T1 ATE330002 T1 AT E330002T1 AT 01943246 T AT01943246 T AT 01943246T AT 01943246 T AT01943246 T AT 01943246T AT E330002 T1 ATE330002 T1 AT E330002T1
- Authority
- AT
- Austria
- Prior art keywords
- membrane vesicles
- preparations
- methods
- relates
- present
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 3
- 210000001808 exosome Anatomy 0.000 abstract 2
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 239000012620 biological material Substances 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 238000011026 diafiltration Methods 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 238000003908 quality control method Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/44—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
- C23C16/4401—Means for minimising impurities, e.g. dust, moisture or residual gas, in the reaction chamber
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- C—CHEMISTRY; METALLURGY
- C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
- C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
- C23C16/00—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes
- C23C16/44—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
- C23C16/50—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges
- C23C16/505—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using radio frequency discharges
- C23C16/509—Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges using radio frequency discharges using internal electrodes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/5432—Liposomes or microcapsules
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J37/00—Discharge tubes with provision for introducing objects or material to be exposed to the discharge, e.g. for the purpose of examination or processing thereof
- H01J37/32—Gas-filled discharge tubes
- H01J37/32431—Constructional details of the reactor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials Engineering (AREA)
- Zoology (AREA)
- Mechanical Engineering (AREA)
- Metallurgy (AREA)
- Plasma & Fusion (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/561,205 US6812023B1 (en) | 2000-04-27 | 2000-04-27 | Methods of producing membrane vesicles |
| US09/780,748 US20040241176A1 (en) | 2000-04-27 | 2001-02-09 | Method of producing membrane vesicles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE330002T1 true ATE330002T1 (de) | 2006-07-15 |
Family
ID=27072576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01943246T ATE330002T1 (de) | 2000-04-27 | 2001-04-11 | Verfahren zur herstellung von membranvesikeln |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20040241176A1 (de) |
| EP (1) | EP1278825B1 (de) |
| JP (1) | JP2003531864A (de) |
| CN (1) | CN1426461A (de) |
| AT (1) | ATE330002T1 (de) |
| AU (1) | AU6587301A (de) |
| CA (1) | CA2407225A1 (de) |
| DE (1) | DE60120683D1 (de) |
| EA (1) | EA005425B1 (de) |
| IL (1) | IL152472A0 (de) |
| WO (1) | WO2001082958A2 (de) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002046766A2 (de) | 2000-12-06 | 2002-06-13 | Ecole Polytechnique Federale De Lausanne | Bioanalytisches reagens verfahren zu dessen herstellung und sensorplattformen sowie nachweisverfahren beruhend auf der verwendung des bioanalytischen reagens |
| EP1417229B1 (de) | 2001-08-17 | 2011-06-15 | Exothera L.L.C. | Verfahren und zusammensetzung zum gezielten einbringen in exosome |
| DE60234115D1 (de) | 2001-11-29 | 2009-12-03 | Dandrit Biotech As | Pharmazeutische zusammensetzung zur auslösung einer immunantwort bei einem menschen oder einem tier |
| JP2005528091A (ja) * | 2002-03-14 | 2005-09-22 | アノシス・インコーポレーテッド | T細胞由来小胞の機能化、および免疫原性医薬組成物を製造するためのその使用 |
| KR20030085659A (ko) * | 2002-04-30 | 2003-11-07 | 동부한농화학 주식회사 | 암 치료용 엑소좀 및 그를 이용한 암 백신 |
| KR100519384B1 (ko) * | 2002-08-13 | 2005-10-06 | (주)누백스 | 유전자 이입을 이용한 엑소좀의 제조방법 및 상기 엑소좀의 용도 |
| WO2004073319A2 (en) * | 2003-02-14 | 2004-08-26 | Anosys, Inc. | Methods and compounds for raising antibodies and for screening antibody repertoires |
| FR2852393B1 (fr) * | 2003-03-14 | 2007-04-13 | Univ Aix Marseille Ii | Methode de detection et d'analyse d'organelle immobilises sur biopuce et leurs applications |
| GB0316560D0 (en) * | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| WO2005121369A2 (en) * | 2004-06-02 | 2005-12-22 | Sourcepharm, Inc. | Rna-containing microvesicles and methods therefor |
| US7901921B2 (en) * | 2004-10-22 | 2011-03-08 | Oncolytics Biotech Inc. | Viral purification methods |
| CA2504279A1 (en) * | 2005-04-15 | 2006-10-15 | University Of Saskatchewan | Materials and method of modulating the immune response using t helper-antigen presenting cells |
| US9599611B2 (en) | 2005-04-25 | 2017-03-21 | Trustees Of Boston University | Structured substrates for optical surface profiling |
| CA2676143A1 (en) * | 2007-01-26 | 2008-07-31 | University Of Louisville Research Foundation, Inc. | Modification of exosomal components for use as a vaccine |
| CA2733672C (en) | 2007-08-16 | 2018-09-11 | The Royal Institution For The Advancement Of Learning/Mcgill University | Tumor cell-derived microvesicles |
| US20100255514A1 (en) | 2007-08-16 | 2010-10-07 | The Royal Institution For The Advancement Of Learning/Mcgill University | Tumor cell-derived microvesicles |
| US8617806B2 (en) * | 2008-01-25 | 2013-12-31 | Hansabiomed Ou | Method to measure and characterize microvesicles in the human body fluids |
| US9487837B2 (en) | 2008-10-06 | 2016-11-08 | Morehouse School Of Medicine | Exosome-mediated diagnosis of hepatitis virus infections and diseases |
| US10545149B2 (en) * | 2008-10-06 | 2020-01-28 | Morehouse School Of Medicine | Detection of HIV-related proteins in urine |
| JP2012507300A (ja) | 2008-10-30 | 2012-03-29 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | Rnaパターンを評価する方法 |
| EP2350320A4 (de) | 2008-11-12 | 2012-11-14 | Caris Life Sciences Luxembourg Holdings | Verfahren und systeme zur verwendung von exosomen zur bestimmung von phänotypen |
| WO2010065968A1 (en) * | 2008-12-05 | 2010-06-10 | Myriad Genetics, Inc. | Cancer detection markers |
| US9835618B1 (en) * | 2009-02-06 | 2017-12-05 | Los Alamos National Security, Llc | Discovery, detection and use of biomarkers |
| PT2419144T (pt) | 2009-04-17 | 2019-09-16 | Univ Oxford Innovation Ltd | Composição para a administração de material genético |
| JP5667180B2 (ja) | 2009-07-01 | 2015-02-12 | イオン メディックス インコーポレイテッド | 哺乳類の有核細胞に由来するマイクロベシクル及びその用途 |
| AU2010268367B2 (en) | 2009-07-02 | 2016-10-20 | Ith Immune Therapy Holdings Ab | Exosome based treatment of cancer |
| DK2454588T3 (en) * | 2009-07-16 | 2015-09-28 | Gen Hospital Corp | Nucleic acid |
| EP2475988B1 (de) | 2009-09-09 | 2018-11-14 | The General Hospital Corporation | Verwendung von mikrovesikeln bei der analyse von nukleinsäureprofilen |
| US20130029339A1 (en) | 2009-09-09 | 2013-01-31 | The General Hospital Corporation | Use of microvesicles in analyzing kras mutations |
| AU2011223789A1 (en) | 2010-03-01 | 2012-09-20 | Caris Life Sciences Switzerland Holdings Gmbh | Biomarkers for theranostics |
| KR20130043104A (ko) | 2010-04-06 | 2013-04-29 | 카리스 라이프 사이언스 룩셈부르크 홀딩스 | 질병용 순환 생물학적 지표들 |
| EP2578236B1 (de) | 2010-05-26 | 2016-03-30 | Micromedmark Biotech Co., Ltd | Herstellung von mikrovesikel-si-rna-komplexen und ihre verwendung bei der behandlung von aids |
| WO2011147086A1 (zh) * | 2010-05-26 | 2011-12-01 | 江苏命码生物科技有限公司 | 载有干扰核糖核酸的细胞微粒子、其制备方法及其应用 |
| WO2012031008A2 (en) | 2010-08-31 | 2012-03-08 | The General Hospital Corporation | Cancer-related biological materials in microvesicles |
| CA2817111C (en) | 2010-11-10 | 2019-03-05 | Exosome Diagnostics, Inc. | Method for isolation of nucleic acid containing particles and extraction of nucleic acids therefrom |
| SG183579A1 (en) * | 2011-02-11 | 2012-09-27 | Agency Science Tech & Res | Methods of detecting therapeutic exosomes |
| ITNA20110012A1 (it) * | 2011-03-14 | 2012-09-15 | Amal Raj Delfin Albert | Procedura di isolamento e di purificazione degli esosomi urinari per la ricerca di biomarcatori proteici |
| KR20140076571A (ko) * | 2011-09-22 | 2014-06-20 | 유니버시다드 데 로스 안데스 | 급성 신장 손상의 조기 모니터링, 진단 및/또는 예후 방법 |
| GB201121070D0 (en) | 2011-12-07 | 2012-01-18 | Isis Innovation | composition for delivery of biotherapeutics |
| US9879254B2 (en) | 2012-01-18 | 2018-01-30 | The General Hosptial Corporation | Targeting RNAs to microvesicles |
| CN103479682B (zh) * | 2012-06-14 | 2015-03-11 | 苏州恒宇生物科技有限公司 | 一种植物来源活性成分-纳米级膜性囊泡的制备方法 |
| AU2013302526B2 (en) | 2012-08-15 | 2018-03-22 | The University Of Chicago | Exosome-based therapeutics against neurodegenerative disorders |
| US20140186293A1 (en) * | 2012-12-31 | 2014-07-03 | University Of Louisville Research Foundation, Inc. | Immunoglobulin-bound extracellular vesicles and uses thereof |
| EP2983721B2 (de) | 2013-04-12 | 2021-01-20 | Evox Therapeutics Limited | Vesikel zur abgabe von therapeutika |
| CN104274828B (zh) * | 2013-07-04 | 2017-11-17 | 复旦大学 | IFN‑α处理细胞所分泌外体在制备抑制肝炎病毒的药物中的应用 |
| CN105658782B (zh) | 2013-10-25 | 2018-08-07 | 凸版印刷株式会社 | 膜囊泡回收设备、膜囊泡回收方法及膜囊泡分析方法 |
| EP3173143A4 (de) | 2014-07-24 | 2018-06-27 | Toppan Printing Co., Ltd. | Lipidmembranstruktur, immobilisierungsträger für lipidmembranstruktur und verfahren zur zellfusion |
| US10329323B2 (en) | 2014-07-25 | 2019-06-25 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Method for purifying antibodies using PBS |
| JP6921809B2 (ja) | 2015-09-22 | 2021-08-18 | トラスティーズ オブ ボストン ユニバーシティ | ナノ小胞の多重表現型決定法 |
| WO2017066454A2 (en) | 2015-10-14 | 2017-04-20 | X-Therma, Inc. | Compositions and methods for reducing ice crystal formation |
| AU2017214541B2 (en) | 2016-02-05 | 2024-03-21 | NanoView Biosciences, Inc. | Detection of exosomes having surface markers |
| WO2017204187A1 (ja) | 2016-05-24 | 2017-11-30 | 公益財団法人がん研究会 | 細胞外小胞回収方法及び細胞外小胞用容器 |
| GB2552473A (en) * | 2016-07-21 | 2018-01-31 | Evox Therapeutics Ltd | Surface decoration of extracellular vesicles |
| US20200046766A1 (en) * | 2016-10-13 | 2020-02-13 | Vbc Holdings Llc | Cancer stem cell exosomes |
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| CN107907689A (zh) * | 2017-10-10 | 2018-04-13 | 北京大学 | 外泌体蛋白cd5l的检测方法 |
| NL2019814B1 (en) * | 2017-10-26 | 2019-05-06 | Stichting Het Nederlands Kanker Inst Antoni Van Leeuwenhoek Ziekenhuis | Methods for producing a MHC multimer. |
| JP7337438B2 (ja) | 2018-03-30 | 2023-09-04 | エクソソミクス・ソシエタ・ペル・アチオニ | 血球および血小板由来の細胞外小胞を困窮化させた血液または血液誘導体を得るための中空糸の使用 |
| EP3803332A1 (de) | 2018-06-01 | 2021-04-14 | NanoView Biosciences, Inc. | Zusammensetzungen, systeme und verfahren zur verbesserten markierungsfreien und fluoreszenzbasierten detektion von nanopartikeln |
| JP7376887B2 (ja) * | 2019-08-20 | 2023-11-09 | Jfeエンジニアリング株式会社 | 動物細胞の増殖促進方法、連続培養方法及び連続培養装置 |
| JP7513869B2 (ja) | 2020-03-23 | 2024-07-10 | 澁谷工業株式会社 | エクソソーム抽出装置およびエクソソームの抽出方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2766205B1 (fr) * | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| FR2785543B1 (fr) * | 1998-11-05 | 2003-02-28 | Inst Nat Sante Rech Med | Exosomes modifies et utilisations |
-
2001
- 2001-02-09 US US09/780,748 patent/US20040241176A1/en not_active Abandoned
- 2001-04-11 AU AU65873/01A patent/AU6587301A/en not_active Abandoned
- 2001-04-11 EP EP01943246A patent/EP1278825B1/de not_active Expired - Lifetime
- 2001-04-11 DE DE60120683T patent/DE60120683D1/de not_active Expired - Lifetime
- 2001-04-11 WO PCT/EP2001/004173 patent/WO2001082958A2/en not_active Ceased
- 2001-04-11 CN CN01808615A patent/CN1426461A/zh active Pending
- 2001-04-11 AT AT01943246T patent/ATE330002T1/de not_active IP Right Cessation
- 2001-04-11 IL IL15247201A patent/IL152472A0/xx unknown
- 2001-04-11 JP JP2001579831A patent/JP2003531864A/ja active Pending
- 2001-04-11 CA CA002407225A patent/CA2407225A1/en not_active Abandoned
- 2001-04-11 EA EA200201150A patent/EA005425B1/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6587301A (en) | 2001-11-12 |
| WO2001082958A3 (en) | 2002-04-18 |
| US20040241176A1 (en) | 2004-12-02 |
| CN1426461A (zh) | 2003-06-25 |
| IL152472A0 (en) | 2003-05-29 |
| EA200201150A1 (ru) | 2003-04-24 |
| WO2001082958A2 (en) | 2001-11-08 |
| EA005425B1 (ru) | 2005-02-24 |
| JP2003531864A (ja) | 2003-10-28 |
| EP1278825B1 (de) | 2006-06-14 |
| DE60120683D1 (de) | 2006-07-27 |
| CA2407225A1 (en) | 2001-11-08 |
| EP1278825A2 (de) | 2003-01-29 |
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