DE3864820D1 - Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen. - Google Patents

Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen.

Info

Publication number
DE3864820D1
DE3864820D1 DE8888901029T DE3864820T DE3864820D1 DE 3864820 D1 DE3864820 D1 DE 3864820D1 DE 8888901029 T DE8888901029 T DE 8888901029T DE 3864820 T DE3864820 T DE 3864820T DE 3864820 D1 DE3864820 D1 DE 3864820D1
Authority
DE
Germany
Prior art keywords
hypoxanthines
alkyl
hydroxy
producing
branched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8888901029T
Other languages
English (en)
Inventor
Riccardo Stradi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Co Pharma Corp Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Co Pharma Corp Srl filed Critical Co Pharma Corp Srl
Application granted granted Critical
Publication of DE3864820D1 publication Critical patent/DE3864820D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/28—Oxygen atom
    • C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
DE8888901029T 1987-01-14 1988-01-04 Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen. Expired - Lifetime DE3864820D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8719083A IT1215339B (it) 1987-01-14 1987-01-14 Procedimento per la preparazione di 9-(idrossialchil)-ipoxantine
PCT/EP1988/000001 WO1988005437A1 (en) 1987-01-14 1988-01-04 A process for the preparation of 9-(hydroxyalkyl)-hypoxanthines

Publications (1)

Publication Number Publication Date
DE3864820D1 true DE3864820D1 (de) 1991-10-17

Family

ID=11154399

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888901029T Expired - Lifetime DE3864820D1 (de) 1987-01-14 1988-01-04 Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen.

Country Status (7)

Country Link
EP (1) EP0355085B1 (de)
JP (1) JPH0813817B2 (de)
AT (1) ATE67201T1 (de)
AU (1) AU605837B2 (de)
DE (1) DE3864820D1 (de)
IT (1) IT1215339B (de)
WO (1) WO1988005437A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62208295A (ja) * 1986-03-07 1987-09-12 Nippon Kayaku Co Ltd ヒポキサンチン塩基を有する新規化合物およびその製造法
US6110923A (en) * 1994-06-22 2000-08-29 Biochem Pharma Inc. Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity
GB2451594A (en) * 2006-03-15 2009-02-04 Csir Modulation of phosphoryl transferase activity of glutamine synthetase
CN101438288A (zh) * 2006-03-15 2009-05-20 Csir公司 谷氨酰胺合成酶的磷酰基转移酶活性的调节

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4221910A (en) * 1978-09-15 1980-09-09 Newport Pharmaceuticals International, Inc. 9-(Hydroxy alkyl)purines
US4221909A (en) * 1978-09-15 1980-09-09 Sloan-Kettering Institute For Cancer Research P-Acetamidobenzoic acid salts of 9-(hydroxyalkyl) purines
YU47791B (sr) * 1988-01-20 1996-01-09 Regents Of The University Of Minnesota Postupak za dobijanje dideoksihidrokar-bocikličnih nukleozida

Also Published As

Publication number Publication date
ATE67201T1 (de) 1991-09-15
JPH0813817B2 (ja) 1996-02-14
AU1226588A (en) 1988-08-10
JPH02501924A (ja) 1990-06-28
WO1988005437A1 (en) 1988-07-28
EP0355085B1 (de) 1991-09-11
IT8719083A0 (it) 1987-01-14
EP0355085A1 (de) 1990-02-28
AU605837B2 (en) 1991-01-24
IT1215339B (it) 1990-02-08

Similar Documents

Publication Publication Date Title
DE68906705D1 (de) Verfahren zur herstellung von baccatin-iii-derivaten und von desacetyl-10-baccatin-iii.
PT85293A (de) Loesungen von oxazaphosphorinen mit verbesserter stabilitaet und verfahren zu deren herstellung
ATE43344T1 (de) Neue 1-hydroxy-1,1-diphosphonsaeureverbindungen, verf. zu ihrer herstellung u. pharmakologische zubereitungen, insb. zur behandlung von knochentumoren.
ATE28187T1 (de) Polyprenylcarbonsaeureamide und verfahren zu ihrer herstellung.
DE3884644D1 (de) Verfahren zur Herstellung von 5'-Inosinsäure.
ATE49957T1 (de) Adamantanamin-derivate, verfahren zur herstellung und diese enthaltende heilmittel.
DE3864820D1 (de) Verfahren zur herstellung von 9-(hydroxy-alkyl) hypoxanthinen.
ATE47861T1 (de) Verfahren zur herstellung von nphosphonomethylglycin.
ATE70831T1 (de) Verfahren zur herstellung von 1-hydroxyalkyl-5nitro-imidazolen.
ATE70837T1 (de) Allylmercaptoacetyl-sydnonimine, verfahren zu ihrer herstellung und ihre verwendung.
ATE41154T1 (de) Verfahren zur herstellung alkanphosphoniger saeuren.
ATE60780T1 (de) Verfahren zur herstellung von alkyloligoglycosiden.
KR830008990A (ko) 2-아미노-3-(할로벤조일)-메틸페닐아세트산 유도체의 제조방법
ATE44961T1 (de) Substituierte o-sulfonyl-glycosylamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel.
ATE69042T1 (de) Verfahren zur herstellung von styroliertem hydrochinon.
ATE34747T1 (de) Verfahren zur herstellung von thiotetronsaeure.
ATE43342T1 (de) Verfahren zur herstellung von hydrogeno- oder halogenosilanen.
DE68903570D1 (de) Verfahren zur herstellung von hydroxyalkylierungsmitteln, die erhaltenen mittel und deren verwendung.
ATE41161T1 (de) Verfahren zur herstellung von 17-alpha-acyloxy-6- chlor-1-alpha, 2-alpha-methylen-4,6-pregnadien- 3,20-dionen.
ATE62235T1 (de) Verfahren zur herstellung von 6-amino-3-hydrazino-pyridazinderivaten.
ATE195115T1 (de) Verfahren zur herstellung von 5,6-dihydroxy-2- amino-1,2,3,4-tetrahydronaphthalin-derivaten
ATE16696T1 (de) Verfahren zur herstellung von 3-alkyl-6-methylbeta-resorcylsaeureestern.
AU6306886A (en) Alkylcarboxamides of pyridylalkylamines, their preparation and their use in human and veterinary medicine
ATE25680T1 (de) Verfahren zur herstellung von 4-amino-5-dialkoxy- methylpyrimidinderivaten.
ATE27804T1 (de) Tetra-alkyl-2,2,5,5-cyclohexanon-4-ol-1 und ihre sulfonierte derivate, verfahren und zwischenprodukte zur ihrer herstellung und ihre verwendung zur herstellung von ciscyclopropanlaktonen.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.,

8328 Change in the person/name/address of the agent

Free format text: TUERK, D., DIPL.-CHEM. DR.RER.NAT. GILLE, C., DIPL.-ING. HRABAL, U., DIPL.-CHEM. DR.RER.NAT. LEIFERT, E., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 40593 DUESSELDORF