DE3650664D1 - Verwendung von promotoren von filamentösen pilzen - Google Patents
Verwendung von promotoren von filamentösen pilzenInfo
- Publication number
- DE3650664D1 DE3650664D1 DE3650664T DE3650664T DE3650664D1 DE 3650664 D1 DE3650664 D1 DE 3650664D1 DE 3650664 T DE3650664 T DE 3650664T DE 3650664 T DE3650664 T DE 3650664T DE 3650664 D1 DE3650664 D1 DE 3650664D1
- Authority
- DE
- Germany
- Prior art keywords
- coding regions
- expression
- foreign
- aspergillus
- secretion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2422—Alpha-amylase (3.2.1.1.) from plant source
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
- C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Botany (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Yarns And Mechanical Finishing Of Yarns Or Ropes (AREA)
- Mushroom Cultivation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Enzymes And Modification Thereof (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Looms (AREA)
- Treatment Of Sludge (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA479135 | 1985-04-15 | ||
US06/811,404 US5198345A (en) | 1985-04-15 | 1985-12-20 | Vectors in use in filamentous fungi |
PCT/GB1986/000209 WO1986006097A1 (en) | 1985-04-15 | 1986-04-14 | Promoters of filamentous fungi and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3650664D1 true DE3650664D1 (de) | 1998-02-12 |
DE3650664T2 DE3650664T2 (de) | 1998-04-16 |
Family
ID=25670651
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3650783T Expired - Lifetime DE3650783T2 (de) | 1985-04-15 | 1986-04-14 | Verwendung des Glucoamylasepromotors aus Apergillus |
DE3650664T Expired - Fee Related DE3650664T2 (de) | 1985-04-15 | 1986-04-14 | Verwendung von promotoren von filamentösen pilzen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3650783T Expired - Lifetime DE3650783T2 (de) | 1985-04-15 | 1986-04-14 | Verwendung des Glucoamylasepromotors aus Apergillus |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0284603B1 (de) |
JP (1) | JP2868179B2 (de) |
AT (2) | ATE161881T1 (de) |
AU (1) | AU606033B2 (de) |
DE (2) | DE3650783T2 (de) |
WO (1) | WO1986006097A1 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8508800D0 (en) * | 1985-04-04 | 1985-05-09 | Glaxo Group Ltd | Microbiological process |
US6004785A (en) | 1985-08-29 | 1999-12-21 | Genencor International Inc. | Heterologous polypeptides expressed in filamentous fungi, processes for making same, and vectors for making same |
US5364770A (en) * | 1985-08-29 | 1994-11-15 | Genencor International Inc. | Heterologous polypeptides expressed in aspergillus |
EP0215594B2 (de) * | 1985-08-29 | 2003-10-15 | Genencor International, Inc. | Expression von heterologen Polypeptiden in filamentösen Pilzen, Verfahren zu deren Herstellung und Vektoren zu deren Herstellung |
US4935349A (en) * | 1986-01-17 | 1990-06-19 | Zymogenetics, Inc. | Expression of higher eucaryotic genes in aspergillus |
US5766912A (en) * | 1986-03-17 | 1998-06-16 | Novo Nordisk A/S | Humicola lipase produced in aspergillus |
US5536661A (en) * | 1987-03-10 | 1996-07-16 | Novo Nordisk A/S | Process for the production of protein products in aspergillus |
FI872102A (fi) * | 1986-06-06 | 1987-12-07 | Panlabs Inc | Expressionssystem hos filamentala fungi. |
GB8702475D0 (en) | 1987-02-04 | 1987-03-11 | Ciba Geigy Ag | Expression system |
US5447862A (en) * | 1987-02-04 | 1995-09-05 | Ciba-Geigy Corporation | Pectin lyase genes of aspergillus niger |
US5252726A (en) * | 1987-09-04 | 1993-10-12 | Novo Nordisk A/S | Promoters for use in aspergillus |
EP0383779B2 (de) * | 1987-09-04 | 2000-05-31 | Novo Nordisk A/S | VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN $i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN $i(ASPERGILLUS) |
DE68913846T3 (de) * | 1988-07-28 | 2002-10-02 | Novartis Ag | Expressionssystem. |
US5162228A (en) * | 1988-12-28 | 1992-11-10 | Takeda Chemical Industries, Ltd. | Gylceraldehyde-3-phosphate dehydrogenase gene and promoter |
CA2034487C (en) * | 1989-06-16 | 2000-08-29 | Virgil B. Lawlis | Dna sequences, vectors, and fusion polypeptides to increase secretion of desired polypeptides from filamentous fungi |
JP2995770B2 (ja) * | 1989-12-15 | 1999-12-27 | 吉富製薬株式会社 | 異種蛋白質の製造方法 |
JPH05505308A (ja) * | 1990-03-13 | 1993-08-12 | ハワイ・バイオテクノロジー・グループ・インコーポレイテツド | アオパンカビ発現システム |
DE69332607T2 (de) * | 1992-03-04 | 2003-05-08 | Genencor Int | Herstellung von -i(aspergillus niger katalase-r) |
US5382658A (en) * | 1992-04-03 | 1995-01-17 | Allelix Biopharmaceuticals Inc. | Stability-enhanced variants of parathyroid hormone |
CA2098639A1 (en) * | 1992-06-19 | 1993-12-20 | K. Anne Kronis | Bone stimulating, non-vasoactive parathyroid hormone variants |
EP0673429B1 (de) * | 1992-12-10 | 2002-06-12 | Dsm N.V. | Herstellung von heterologen proteinen in filamentösen fungi |
GB9316883D0 (en) * | 1993-08-13 | 1993-09-29 | Univ Leeds | Production of heterologous peptices |
ES2080689B1 (es) * | 1994-04-21 | 1996-09-01 | Urquima Sa | Procedimiento de obtencion de un edulcorante natural proteico. |
GB9515941D0 (en) | 1995-08-03 | 1995-10-04 | Zeneca Ltd | DNA constructs |
DE69631127T2 (de) * | 1995-05-18 | 2004-07-08 | Genencor International, Inc., Palo Alto | Glykosyltransferase expression in aspergillus |
GB9907461D0 (en) | 1999-03-31 | 1999-05-26 | King S College London | Neurite regeneration |
US8372620B2 (en) | 1998-12-23 | 2013-02-12 | Dupont Nutrition Biosciences Aps | Bacterial xylanases |
GB0020498D0 (en) | 2000-08-18 | 2000-10-11 | Sterix Ltd | Compound |
SK288130B6 (sk) | 2000-09-21 | 2013-10-02 | Basf Aktiengesellschaft | Xylanase polypeptide, a polynucleotide, a vector, a host cell, method of polypeptide production, method of use of polypeptide |
AU2002219709B2 (en) | 2000-12-07 | 2007-06-14 | Dsm Ip Assets B.V. | Method for the prevention or reduction of haze in beverages |
ES2301579T3 (es) | 2000-12-07 | 2008-07-01 | Dsm Ip Assets B.V. | Prolil endoproteasa a partir de aspergillus niger. |
GB0116453D0 (en) | 2001-07-05 | 2001-08-29 | Imp College Innovations Ltd | Method |
BR0311655A (pt) | 2002-06-07 | 2005-03-15 | Dsm Ip Assets Bv | Método melhorado para a prevenção ou redução de turbidez em bebidas |
TWI328612B (en) | 2002-07-25 | 2010-08-11 | Dsm Ip Assets Bv | Genes and their encoded polypeptides involved in the biosynthetic pathway of vitamin b12, vectors and host cells comprising the genes, and process for producing vitamin b12 |
GB0403864D0 (en) | 2004-02-20 | 2004-03-24 | Ucl Ventures | Modulator |
AU2006316397B2 (en) | 2005-11-28 | 2013-03-28 | Dsm Ip Assets B.V. | Enzyme preparations yielding a clean taste |
GB0600406D0 (en) | 2006-01-10 | 2006-02-15 | Univ Bath | Crystal |
BRPI0807768A2 (pt) | 2007-02-20 | 2014-06-24 | Dsm Ip Assests Bv | Nova sialidase. |
WO2008113799A1 (en) | 2007-03-22 | 2008-09-25 | Dsm Ip Assets B.V. | Novel lysyl oxidases |
JP2010535484A (ja) | 2007-08-08 | 2010-11-25 | ノボザイムス バイオファーマ デーコー アクティーゼルスカブ | トランスフェリン変異体と複合体 |
EP2617733A1 (de) | 2009-02-06 | 2013-07-24 | Novozymes Biopharma DK A/S | Aufreinigungsverfahren |
EP2396347B1 (de) | 2009-02-11 | 2017-04-12 | Albumedix A/S | Varianten und konjugate von albumin |
WO2011101339A2 (en) | 2010-02-18 | 2011-08-25 | Dsm Ip Assets B.V. | Fermentation broth and filtration filter cake and uses thereof |
WO2012007446A1 (en) | 2010-07-13 | 2012-01-19 | Dsm Ip Assets B.V. | Use of a mutarotase in the production of dried powders |
WO2012007445A1 (en) | 2010-07-13 | 2012-01-19 | Dsm Ip Assets B.V. | Mutarotase in crystallization |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1207687A (en) * | 1982-07-07 | 1986-07-15 | Alan M. Lambowitz | Filamentous fungi functional replicating extrachromosomal element |
NO840200L (no) * | 1983-01-28 | 1984-07-30 | Cefus Corp | Glukoamylase cdna. |
NZ207925A (en) * | 1983-04-25 | 1988-05-30 | Genentech Inc | Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture |
EP0136907A3 (de) * | 1983-10-03 | 1986-12-30 | Genentech, Inc. | Xenogeneisches Expressionskontrollsystem, Verfahren zu dessen Verwendung, dieses enthaltende Expressionsvektoren, mit denselben transformierte Zellen und daraus hergestellte heterolose Proteine |
CA1341130C (en) * | 1984-07-27 | 2000-10-31 | Adrianus Marinus Ledeboer | Use of oxidoreductases in bleaching and/or detergent compositions and their preparation by microorganisms engineered by recombinant dna technology |
EP0191221A1 (de) * | 1984-10-24 | 1986-08-20 | The Regents Of The University Of California | Vektoren zur Transformation von Ascomyceten |
ES8605580A1 (es) * | 1984-11-07 | 1986-03-16 | Antibioticos Sa | Un procedimiento para manipular por ingenieria genetica ce- phalosporium acremonium productor de cefalosporina |
EP0215594B2 (de) * | 1985-08-29 | 2003-10-15 | Genencor International, Inc. | Expression von heterologen Polypeptiden in filamentösen Pilzen, Verfahren zu deren Herstellung und Vektoren zu deren Herstellung |
-
1986
- 1986-04-14 AU AU56986/86A patent/AU606033B2/en not_active Expired
- 1986-04-14 EP EP86902449A patent/EP0284603B1/de not_active Expired - Lifetime
- 1986-04-14 WO PCT/GB1986/000209 patent/WO1986006097A1/en active IP Right Grant
- 1986-04-14 DE DE3650783T patent/DE3650783T2/de not_active Expired - Lifetime
- 1986-04-14 DE DE3650664T patent/DE3650664T2/de not_active Expired - Fee Related
- 1986-04-14 AT AT86902449T patent/ATE161881T1/de not_active IP Right Cessation
- 1986-04-14 AT AT96116202T patent/ATE253119T1/de not_active IP Right Cessation
-
1994
- 1994-09-08 JP JP6214613A patent/JP2868179B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU5698686A (en) | 1986-11-05 |
DE3650783D1 (de) | 2003-12-04 |
ATE161881T1 (de) | 1998-01-15 |
AU606033B2 (en) | 1991-01-31 |
JP2868179B2 (ja) | 1999-03-10 |
DE3650664T2 (de) | 1998-04-16 |
WO1986006097A1 (en) | 1986-10-23 |
EP0284603A1 (de) | 1988-10-05 |
JPH07163389A (ja) | 1995-06-27 |
EP0284603B1 (de) | 1998-01-07 |
ATE253119T1 (de) | 2003-11-15 |
DE3650783T2 (de) | 2004-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: DSM N.V., HEERLEN, NL |
|
8327 | Change in the person/name/address of the patent owner |
Owner name: DSM IP ASSETS B.V., HEERLEN, NL |
|
8339 | Ceased/non-payment of the annual fee |