DE3621846C2 - - Google Patents
Info
- Publication number
- DE3621846C2 DE3621846C2 DE19863621846 DE3621846A DE3621846C2 DE 3621846 C2 DE3621846 C2 DE 3621846C2 DE 19863621846 DE19863621846 DE 19863621846 DE 3621846 A DE3621846 A DE 3621846A DE 3621846 C2 DE3621846 C2 DE 3621846C2
- Authority
- DE
- Germany
- Prior art keywords
- liquid
- gas
- aid
- lyophobic
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 claims description 35
- 239000007789 gas Substances 0.000 claims description 13
- 238000002347 injection Methods 0.000 claims description 11
- 239000007924 injection Substances 0.000 claims description 11
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 10
- 239000001257 hydrogen Substances 0.000 claims description 10
- 229910052739 hydrogen Inorganic materials 0.000 claims description 10
- 238000011161 development Methods 0.000 claims description 7
- 239000011148 porous material Substances 0.000 claims description 6
- 239000012528 membrane Substances 0.000 claims description 5
- 239000000126 substance Substances 0.000 claims description 5
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 3
- 238000009792 diffusion process Methods 0.000 claims description 3
- 239000001301 oxygen Substances 0.000 claims description 3
- 229910052760 oxygen Inorganic materials 0.000 claims description 3
- 239000004033 plastic Substances 0.000 claims description 3
- 229920003023 plastic Polymers 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 claims description 2
- 239000003792 electrolyte Substances 0.000 claims description 2
- 238000001802 infusion Methods 0.000 claims description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 claims 1
- 229910001882 dioxygen Inorganic materials 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 239000012476 oxidizable substance Substances 0.000 claims 1
- 239000003186 pharmaceutical solution Substances 0.000 claims 1
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 12
- 102000004877 Insulin Human genes 0.000 description 6
- 108090001061 Insulin Proteins 0.000 description 6
- 229940125396 insulin Drugs 0.000 description 6
- 239000003814 drug Substances 0.000 description 5
- 239000000243 solution Substances 0.000 description 4
- -1 Polyethylene Polymers 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 238000012937 correction Methods 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000002940 repellent Effects 0.000 description 1
- 239000005871 repellent Substances 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/141—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor with capillaries for restricting fluid flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863621846 DE3621846A1 (de) | 1986-06-30 | 1986-06-30 | Gasbetriebene dosiervorrichtung |
| AU75162/87A AU7516287A (en) | 1986-06-30 | 1987-06-13 | Gas-propelled dosing device |
| EP19870903853 EP0278954B1 (de) | 1986-06-30 | 1987-06-13 | Gasbetriebene dosiervorrichtung |
| PCT/DE1987/000271 WO1988000065A1 (fr) | 1986-06-30 | 1987-06-13 | Dispositif de dosage mu au gaz |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863621846 DE3621846A1 (de) | 1986-06-30 | 1986-06-30 | Gasbetriebene dosiervorrichtung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3621846A1 DE3621846A1 (de) | 1988-01-21 |
| DE3621846C2 true DE3621846C2 (enExample) | 1992-04-02 |
Family
ID=6304020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19863621846 Granted DE3621846A1 (de) | 1986-06-30 | 1986-06-30 | Gasbetriebene dosiervorrichtung |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0278954B1 (enExample) |
| AU (1) | AU7516287A (enExample) |
| DE (1) | DE3621846A1 (enExample) |
| WO (1) | WO1988000065A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3711714A1 (de) * | 1987-04-07 | 1988-10-27 | Winsel August | Vorrichtung zur foerderung pastoeser massen und fluessigkeiten und verfahren zur befuellung und zum betrieb |
| DE3882202D1 (en) * | 1987-05-18 | 1993-08-12 | Disetronic Ag | Infusionsgeraet. |
| FR2631551A1 (fr) * | 1988-05-17 | 1989-11-24 | Soudant Jacques | Systeme pour faire une perfusion d'un liquide dans une voie sanguine notamment d'un etre humain |
| US5062834A (en) * | 1989-02-24 | 1991-11-05 | Product Development (S.G.Z.) Ltd | Device for dispensing a liquid particularly useful for delivering medicaments at a predetermined rate |
| DE4121351C2 (de) * | 1991-06-28 | 1994-12-15 | Winsel August | Fördervorrichtung mit einer Gasentwicklungszelle für fließfähige Medien |
| EP0598867B1 (de) * | 1992-06-15 | 1997-03-05 | WYSSMANN, Max | Vorrichtung zur gezielten, steuerbaren abgabe einer flüssigkeit oder einer viskosen masse |
| DE19519279A1 (de) * | 1994-12-07 | 1996-08-22 | Wolfgang Dr Med Wagner | Verfahren und Einrichtung zur Saug-Druckinjektion |
| DE19711605C1 (de) * | 1997-03-20 | 1998-06-25 | August Prof Dr Rer Nat Winsel | Gasbetriebene Fördervorrichtung für fließfähige Medien, bei der das Gasentwicklungssystem das Gas in einer vorgegebenen zeitlichen Menge vorzugsweise aus Gasentwicklungszellen erzeugt, mit einer Anzeige der Kolbenstellung |
| DE19907744A1 (de) * | 1999-02-23 | 2000-08-24 | Backes Claus H | Injektionsgerät |
| DE19909014C2 (de) * | 1999-03-02 | 2001-01-25 | August Winsel | Kolben und damit ausgerüstete, gasbetriebene Fördervorrichtung für fließfähige Medien, bei der das Gasentwicklungssystem das Gas in einer vorgegebenen zeitlichen Menge vorzugsweise aus Gasentwicklungszellen erzeugt |
| DE19925481A1 (de) | 1999-06-03 | 2000-12-14 | August Winsel | Vorrichtung zur Sammlung von pastösen Massen, Flüssigkeiten, Gasen und mobilen Objekten |
| EP1183059A1 (en) * | 1999-06-08 | 2002-03-06 | Medical Research Group, Inc. | Method and apparatus for infusing liquids using a chemical reaction in an implanted infusion device |
| DE10051232A1 (de) * | 2000-10-16 | 2002-04-25 | August Winsel | Sammelvorrichtung mit Diffusionssenke |
| KR100472577B1 (ko) * | 2001-11-02 | 2005-02-22 | 김용년 | 액체공급장치 |
| DE10360185A1 (de) * | 2003-12-20 | 2005-08-04 | Max Wyssmann | Vorrichtung zur gezielten, steuerbaren Abgabe oder zum Ansaugen einer Flüssigkeit oder einer viskosen Masse |
| DE10360186A1 (de) * | 2003-12-20 | 2005-08-04 | Max Wyssmann | Vorrichtung zur gezielten, steuerbaren Abgabe einer Flüssigkeit oder einer viskosen Masse |
| IL169807A (en) | 2005-07-21 | 2015-03-31 | Steadymed Ltd | Device for administering a drug |
| US9687186B2 (en) | 2005-07-21 | 2017-06-27 | Steadymed Ltd. | Drug delivery device |
| IL175460A (en) | 2006-05-07 | 2011-05-31 | Doron Aurbach | Drug delivery device |
| CN101432033A (zh) * | 2006-04-28 | 2009-05-13 | 皇家飞利浦电子股份有限公司 | 具有至少一种气体释放材料的微泵 |
| DE102007054753A1 (de) | 2007-07-30 | 2009-02-19 | Winsel, August, Prof. Dipl.-Phys. Dr. | Verfahren und Vorrichtung zur ökonomischen und ökologischen Bekämpfung von Schädlingen in und an Obst- und Nutzholzbäumen |
| EP2100633B1 (en) | 2008-03-10 | 2011-01-05 | F. Hoffmann-La Roche AG | Medical device and charging station therefor |
| WO2012042517A1 (en) | 2010-09-27 | 2012-04-05 | Steadymed, Ltd. | Size-efficient drug-delivery device |
| WO2013136327A1 (en) | 2012-03-15 | 2013-09-19 | Steadymed Ltd. | Enhanced infusion-site pain-reduction for drug-delivery devices |
| US9724462B2 (en) | 2012-03-19 | 2017-08-08 | Steadymed Ltd. | Fluid-connection mechanism for patch-pumps |
| US10463847B2 (en) | 2015-06-11 | 2019-11-05 | Steadymed Ltd. | Infusion set |
| CN107485762B (zh) * | 2017-09-07 | 2020-09-01 | 山东省千佛山医院 | 一种注射泵 |
| CN109771739B (zh) * | 2019-03-01 | 2021-02-26 | 浙江师范大学 | 一种压电片驱动的药品推注器 |
| CN109876239B (zh) * | 2019-03-01 | 2021-03-16 | 浙江师范大学 | 一种压电片驱动的注射系统 |
| CN110259539A (zh) * | 2019-06-06 | 2019-09-20 | 上海柯来浦能源科技有限公司 | 利用金属储氢材料氢能发电系统 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1099132B (de) * | 1958-08-02 | 1961-02-09 | Leitz Ernst Gmbh | Injektionsspritze |
| US4267836A (en) * | 1976-11-12 | 1981-05-19 | Whitney Douglass G | Injection device and method |
| AU5924380A (en) * | 1979-06-11 | 1980-12-18 | Unisearch Limited | Infusion apparatus |
| EP0209644A1 (en) * | 1985-05-02 | 1987-01-28 | Ivac Corporation | Electrochemically driven drug dispenser |
| DE3532335A1 (de) * | 1985-09-11 | 1987-03-12 | Winsel August | Galvanische zelle zur entwicklung von wasserstoff bzw. sauerstoff |
-
1986
- 1986-06-30 DE DE19863621846 patent/DE3621846A1/de active Granted
-
1987
- 1987-06-13 AU AU75162/87A patent/AU7516287A/en not_active Abandoned
- 1987-06-13 EP EP19870903853 patent/EP0278954B1/de not_active Expired - Lifetime
- 1987-06-13 WO PCT/DE1987/000271 patent/WO1988000065A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU7516287A (en) | 1988-01-29 |
| WO1988000065A1 (fr) | 1988-01-14 |
| EP0278954B1 (de) | 1992-01-22 |
| DE3621846A1 (de) | 1988-01-21 |
| EP0278954A1 (de) | 1988-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OP8 | Request for examination as to paragraph 44 patent law | ||
| D2 | Grant after examination | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: GCT GAS-CELL-TEC AG, HERZOGENBUCHSEE, CH |
|
| 8328 | Change in the person/name/address of the agent |
Free format text: GRUENECKER, A., DIPL.-ING. KINKELDEY, H., DIPL.-ING. DR.-ING. STOCKMAIR, W., DIPL.-ING. DR.-ING. AE.E. CAL TECH SCHUMANN, K., DIPL.-PHYS. DR.RER.NAT. JAKOB, P., DIPL.-ING. BEZOLD, G., DIPL.-CHEM. DR.RER.NAT. MEISTER, W., DIPL.-ING. HILGERS, H., DIPL.-ING. MEYER-PLATH, H., DIPL.-ING. DR.-ING. EHNOLD, A., DIPL.-ING. SCHUSTER, T., DIPL.-PHYS. GOLDBACH, K., DIPL.-ING.DR.-ING. AUFENANGER, M., DIPL.-ING. KLITZSCH, G., DIPL.-ING., PAT.-ANWAELTE, 8000 MUENCHEN |
|
| 8381 | Inventor (new situation) |
Free format text: WINSEL, AUGUST, PROF. DR., 6233 KELKHEIM, DE |
|
| 8363 | Opposition against the patent | ||
| 8365 | Fully valid after opposition proceedings |