DE3587840T2 - Für das Polypeptid des T-Zellantigenreceptors kodierende Nukleinsäure. - Google Patents

Für das Polypeptid des T-Zellantigenreceptors kodierende Nukleinsäure.

Info

Publication number
DE3587840T2
DE3587840T2 DE3587840T DE3587840T DE3587840T2 DE 3587840 T2 DE3587840 T2 DE 3587840T2 DE 3587840 T DE3587840 T DE 3587840T DE 3587840 T DE3587840 T DE 3587840T DE 3587840 T2 DE3587840 T2 DE 3587840T2
Authority
DE
Germany
Prior art keywords
cell
nucleic acid
antigen receptor
polypeptide
cell antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3587840T
Other languages
English (en)
Other versions
DE3587840D1 (de
Inventor
Tak W Mak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ontario Cancer Institute
Original Assignee
Ontario Cancer Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ontario Cancer Institute filed Critical Ontario Cancer Institute
Publication of DE3587840D1 publication Critical patent/DE3587840D1/de
Application granted granted Critical
Publication of DE3587840T2 publication Critical patent/DE3587840T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE3587840T 1984-01-13 1985-01-14 Für das Polypeptid des T-Zellantigenreceptors kodierende Nukleinsäure. Expired - Lifetime DE3587840T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57069484A 1984-01-13 1984-01-13
US06/577,526 US4713332A (en) 1984-01-13 1984-02-06 T cell specific CDNA clone

Publications (2)

Publication Number Publication Date
DE3587840D1 DE3587840D1 (de) 1994-07-14
DE3587840T2 true DE3587840T2 (de) 1994-09-15

Family

ID=27075378

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3587840T Expired - Lifetime DE3587840T2 (de) 1984-01-13 1985-01-14 Für das Polypeptid des T-Zellantigenreceptors kodierende Nukleinsäure.

Country Status (6)

Country Link
US (1) US4713332A (de)
EP (2) EP0149548B1 (de)
JP (4) JP2565486B2 (de)
AT (1) ATE106940T1 (de)
DE (1) DE3587840T2 (de)
HK (1) HK1006854A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4497020A (en) * 1981-06-30 1985-01-29 Ampex Corporation Selective mapping system and method
US4970296A (en) * 1984-03-01 1990-11-13 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
SG70553A1 (en) * 1984-03-01 2000-02-22 Univ Leland Stanford Junior T-cell receptor-specific for antigen polypeptides and related polynucleotides
US4874845A (en) * 1984-06-13 1989-10-17 Massachusetts Institute Of Technology T lymphocyte receptor subunit
US4873190A (en) * 1984-06-13 1989-10-10 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
JP2783404B2 (ja) * 1984-03-01 1998-08-06 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシテイ Ｔ・細胞抗原レセプター特異的ポリペプチドβ−サブユニットをコードする核酸
US4886743A (en) * 1985-04-24 1989-12-12 California Institute Of Technology Diagnostic reagents based on unique sequences within the variable region of the T cell receptor and uses thereof
EP0203403B1 (de) * 1985-05-01 1992-10-28 Asahi Kasei Kogyo Kabushiki Kaisha Zum Erkennen von Tumoren fähige klonierte T-Zelle und ein T-Zellen-Antigenrezeptor
EP0248887B1 (de) * 1985-12-03 1994-12-28 T Cell Sciences, Inc. Zellenfreier t-zellenantigenrezeptor und klinische verwendung
US5024940A (en) * 1987-02-19 1991-06-18 T Cell Sciences, Inc. Nucleic acids encoding the delta chain of the T cell antigen receptor
US5340921A (en) * 1986-07-03 1994-08-23 T Cell Sciences, Inc. Γ, δT cell receptor and methods and detection
US5286653A (en) * 1986-07-03 1994-02-15 T Cell Diagnostics, Inc. Method for detecting the γ,δ T cell receptor
US5260223A (en) * 1986-07-03 1993-11-09 President & Fellows Of Harvard College Methods for detection of human gamma, γ T cell receptor
JPS63221890A (ja) * 1987-03-09 1988-09-14 Iwasaki Electric Co Ltd 有機物含有水の処理方法とその装置
US4835255A (en) * 1987-03-26 1989-05-30 Yale University T-cell membrane protein
EP0296786B1 (de) * 1987-06-23 1996-10-30 The Board Of Trustees Of The Leland Stanford Junior University Innerhalb des alpha-Locus gelegenes T-Zell-Rezeptor-Gen und DNA-Konstruktionen
US5028424A (en) * 1987-10-16 1991-07-02 University Of Georgia Research Foundation Antibodies to receptor and antigen for natural killer and non-specific cytotoxic cells
WO1989003394A1 (en) * 1987-10-16 1989-04-20 University Of Georgia Research Foundation, Inc. Antigen recognized by natural killer and non-specific cytotoxic cells
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
JPH03293086A (ja) * 1989-03-01 1991-12-24 Kiyoshi Kikuchi 溶存酸素の多い水を得る方法と、水中のオゾンを減少させる方法並びに装置
US5196526A (en) * 1989-11-28 1993-03-23 University Of Health Sciences/The Chicago Medical School CDNA clone for T-cell suppressor inducer factor
CA2072356A1 (en) * 1989-12-29 1991-06-30 James L. Urban Diagnosis and treatment of diseases
US6416971B1 (en) 1990-05-15 2002-07-09 E.R. Squibb & Sons, Inc. Soluble single chain T cell receptors
US5747036A (en) * 1991-08-28 1998-05-05 Brigham & Women's Hospital Methods and compositions for detecting and treating a subset of human patients having an autoimmune disease
US5445940A (en) * 1991-08-28 1995-08-29 Brigham & Women's Hospital Methods and compositions for detecting and treating a subset of human patients having an autoimmune disease
US5552300A (en) * 1994-01-13 1996-09-03 T Cell Sciences, Inc. T cell antigen receptor V region proteins and methods of preparation thereof
US6451571B1 (en) 1994-05-02 2002-09-17 University Of Washington Thymidine kinase mutants
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
AU2002220275A1 (en) * 2000-12-08 2002-06-18 The Board Of Trustees Of The University Of Illinois Mutated class ii major histocompatibility proteins
US20080064631A1 (en) * 2006-01-13 2008-03-13 Jeffrey Molldrem T-cell receptors for use in diagnosis and therapy of cancers and autoimmune disease
EP2098536A1 (de) 2008-03-05 2009-09-09 4-Antibody AG Isolation und Identifikation antigen- oder ligandenspezifischer Bindungsproteine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4873190A (en) * 1984-06-13 1989-10-10 Massachusetts Institute Of Technology Heterodimeric T lymphocyte receptor
SG70553A1 (en) * 1984-03-01 2000-02-22 Univ Leland Stanford Junior T-cell receptor-specific for antigen polypeptides and related polynucleotides

Also Published As

Publication number Publication date
HK1006854A1 (en) 1999-03-19
US4713332A (en) 1987-12-15
JPH1057075A (ja) 1998-03-03
JPH08109199A (ja) 1996-04-30
EP0149548A3 (en) 1987-05-20
DE3587840D1 (de) 1994-07-14
JPS6128395A (ja) 1986-02-08
JP2690289B2 (ja) 1997-12-10
JPH0698772A (ja) 1994-04-12
ATE106940T1 (de) 1994-06-15
EP0149548A2 (de) 1985-07-24
EP0593092A1 (de) 1994-04-20
JP2562268B2 (ja) 1996-12-11
EP0149548B1 (de) 1994-06-08
JP2565486B2 (ja) 1996-12-18

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Legal Events

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8339 Ceased/non-payment of the annual fee
8370 Indication related to discontinuation of the patent is to be deleted