DE3582193D1 - Wirksubstanzen enthaltende hydrogelvorrichtungen, worin das konzentrationsprofil der wirksubstanz einen sigmoidalen konzentrationsgradienten zur konstanten freisetzung besitzt, deren herstellung und verwendung. - Google Patents

Wirksubstanzen enthaltende hydrogelvorrichtungen, worin das konzentrationsprofil der wirksubstanz einen sigmoidalen konzentrationsgradienten zur konstanten freisetzung besitzt, deren herstellung und verwendung.

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Publication number
DE3582193D1
DE3582193D1 DE8585810213T DE3582193T DE3582193D1 DE 3582193 D1 DE3582193 D1 DE 3582193D1 DE 8585810213 T DE8585810213 T DE 8585810213T DE 3582193 T DE3582193 T DE 3582193T DE 3582193 D1 DE3582193 D1 DE 3582193D1
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DE
Germany
Prior art keywords
active agent
production
devices containing
gradient
constant release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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DE8585810213T
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German (de)
English (en)
Inventor
Ping I Dr Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
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Ciba Geigy AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Colloid Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE8585810213T 1984-05-10 1985-05-07 Wirksubstanzen enthaltende hydrogelvorrichtungen, worin das konzentrationsprofil der wirksubstanz einen sigmoidalen konzentrationsgradienten zur konstanten freisetzung besitzt, deren herstellung und verwendung. Expired - Lifetime DE3582193D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/608,756 US4624848A (en) 1984-05-10 1984-05-10 Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use

Publications (1)

Publication Number Publication Date
DE3582193D1 true DE3582193D1 (de) 1991-04-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585810213T Expired - Lifetime DE3582193D1 (de) 1984-05-10 1985-05-07 Wirksubstanzen enthaltende hydrogelvorrichtungen, worin das konzentrationsprofil der wirksubstanz einen sigmoidalen konzentrationsgradienten zur konstanten freisetzung besitzt, deren herstellung und verwendung.

Country Status (16)

Country Link
US (1) US4624848A (https=)
EP (1) EP0164311B1 (https=)
JP (1) JPS619A (https=)
AT (1) ATE61731T1 (https=)
AU (1) AU583507B2 (https=)
CA (1) CA1246447A (https=)
DE (1) DE3582193D1 (https=)
DK (1) DK205185A (https=)
ES (1) ES542948A0 (https=)
FI (1) FI851801A7 (https=)
GR (1) GR851114B (https=)
IL (1) IL75129A (https=)
NZ (1) NZ212030A (https=)
PH (1) PH24100A (https=)
PT (1) PT80416B (https=)
ZA (1) ZA853511B (https=)

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EP0164311A3 (en) 1987-06-03
PT80416B (en) 1987-04-16
AU583507B2 (en) 1989-05-04
FI851801A0 (fi) 1985-05-08
ES8603273A1 (es) 1986-01-01
JPS619A (ja) 1986-01-06
GR851114B (https=) 1985-11-25
PH24100A (en) 1990-03-05
CA1246447A (en) 1988-12-13
IL75129A0 (en) 1985-09-29
IL75129A (en) 1989-08-15
EP0164311B1 (en) 1991-03-20
ZA853511B (en) 1985-12-24
DK205185D0 (da) 1985-05-09
EP0164311A2 (en) 1985-12-11
ES542948A0 (es) 1986-01-01
ATE61731T1 (de) 1991-04-15
DK205185A (da) 1985-11-11
AU4221685A (en) 1985-11-14
FI851801L (fi) 1985-11-11
US4624848A (en) 1986-11-25
PT80416A (en) 1985-06-01
FI851801A7 (fi) 1985-11-11
NZ212030A (en) 1988-01-08

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