DE3523634C2 - - Google Patents
Info
- Publication number
- DE3523634C2 DE3523634C2 DE3523634A DE3523634A DE3523634C2 DE 3523634 C2 DE3523634 C2 DE 3523634C2 DE 3523634 A DE3523634 A DE 3523634A DE 3523634 A DE3523634 A DE 3523634A DE 3523634 C2 DE3523634 C2 DE 3523634C2
- Authority
- DE
- Germany
- Prior art keywords
- gene
- urogastrone
- subunit
- plasmid
- recombinant plasmid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 238000000034 method Methods 0.000 claims description 85
- 108090000623 proteins and genes Proteins 0.000 claims description 83
- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 claims description 52
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59137691A JP2554459B2 (ja) | 1984-07-02 | 1984-07-02 | β−ウロガストロン遺伝子、対応プラスミド組換体及び対応形質転換体 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3523634A1 DE3523634A1 (de) | 1986-01-09 |
DE3523634C2 true DE3523634C2 (US06168655-20010102-C00055.png) | 1993-07-08 |
Family
ID=15204546
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19853523634 Granted DE3523634A1 (de) | 1984-07-02 | 1985-07-02 | Ss-urogastron-gen, rekombinant-plasmide, transformanten, deren herstellung und herstellung von ss-urogastron |
Country Status (12)
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4870008A (en) * | 1983-08-12 | 1989-09-26 | Chiron Corporation | Secretory expression in eukaryotes |
GB8507666D0 (en) * | 1985-03-25 | 1985-05-01 | Wellcome Found | Epidermal growth factor production |
US4743679A (en) * | 1986-02-24 | 1988-05-10 | Creative Biomolecules, Inc. | Process for producing human epidermal growth factor and analogs thereof |
US5222978A (en) | 1987-08-26 | 1993-06-29 | United States Surgical Corporation | Packaged synthetic absorbable surgical elements |
US5306289A (en) | 1987-08-26 | 1994-04-26 | United States Surgical Corporation | Braided suture of improved characteristics |
US5226912A (en) | 1987-08-26 | 1993-07-13 | United States Surgical Corporation | Combined surgical needle-braided suture device |
US5366081A (en) | 1987-08-26 | 1994-11-22 | United States Surgical Corporation | Packaged synthetic absorbable surgical elements |
US5472702A (en) * | 1987-08-26 | 1995-12-05 | United States Surgical Corporation | Sterilization of growth factors |
GB2210618B (en) * | 1987-10-08 | 1991-10-16 | British Bio Technology | Synthetic egf gene |
FI891308A (fi) * | 1988-03-24 | 1989-09-25 | Oncogen | Nya polypeptider med tillvaextfaktoraktivitet och dessa kodande nukleinsyrasekvenser. |
US5102789A (en) * | 1989-03-15 | 1992-04-07 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Production of epideramal growth factor in pichia pastoris yeast cells |
US5359831A (en) | 1989-08-01 | 1994-11-01 | United States Surgical Corporation | Molded suture retainer |
CA2059245C (en) * | 1991-02-08 | 2004-07-06 | Michael P. Chesterfield | Method and apparatus for calendering and coating/filling sutures |
WO1994025592A1 (en) * | 1993-04-26 | 1994-11-10 | Daewoong Pharmaceutical Co., Ltd. | A novel gene coding human epidermal growth factor and process for preparing the same |
US5904716A (en) * | 1995-04-26 | 1999-05-18 | Gendler; El | Method for reconstituting cartilage tissue using demineralized bone and product thereof |
JP4057846B2 (ja) | 2002-06-07 | 2008-03-05 | 株式会社アステア | バンパ構造材 |
US20090192554A1 (en) | 2008-01-29 | 2009-07-30 | Confluent Surgical, Inc. | Bioabsorbable block copolymer |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE53166B1 (en) * | 1980-08-05 | 1988-08-03 | Searle & Co | Synthetic urogastrone gene,corresponding plasmid recombinants,transformed cells,production thereof and urogastrone expression |
FR2488557A1 (fr) * | 1980-08-13 | 1982-02-19 | Ducellier & Cie | Dispositif de basculement des projecteurs d'un vehicule automobile |
US4532207A (en) * | 1982-03-19 | 1985-07-30 | G. D. Searle & Co. | Process for the preparation of polypeptides utilizing a charged amino acid polymer and exopeptidase |
WO1983004030A1 (en) * | 1982-05-06 | 1983-11-24 | Applied Molecular Genetics, Inc. | The manufacture and expression of genes for urogastrone and polypeptide analogs thereof |
-
1984
- 1984-07-02 JP JP59137691A patent/JP2554459B2/ja not_active Expired - Lifetime
-
1985
- 1985-06-24 AU AU44111/85A patent/AU599003B2/en not_active Ceased
- 1985-06-24 CA CA000485007A patent/CA1304023C/en not_active Expired - Lifetime
- 1985-06-27 DK DK291885A patent/DK291885A/da not_active Application Discontinuation
- 1985-06-28 SE SE8503228A patent/SE8503228L/ unknown
- 1985-06-28 NL NL8501880A patent/NL192116C/nl not_active IP Right Cessation
- 1985-07-01 IT IT8505195A patent/IT1210142B/it active
- 1985-07-01 KR KR1019850004708A patent/KR920009543B1/ko not_active IP Right Cessation
- 1985-07-01 CH CH2812/85A patent/CH670654A5/de not_active IP Right Cessation
- 1985-07-01 GB GB8516591A patent/GB2162851B/en not_active Expired
- 1985-07-02 FR FR858510072A patent/FR2566799B1/fr not_active Expired
- 1985-07-02 DE DE19853523634 patent/DE3523634A1/de active Granted
Also Published As
Publication number | Publication date |
---|---|
GB2162851A (en) | 1986-02-12 |
DE3523634A1 (de) | 1986-01-09 |
DK291885A (da) | 1986-01-03 |
IT1210142B (it) | 1989-09-06 |
KR860001186A (ko) | 1986-02-24 |
SE8503228L (sv) | 1986-01-03 |
FR2566799A1 (fr) | 1986-01-03 |
AU4411185A (en) | 1986-01-09 |
DK291885D0 (da) | 1985-06-27 |
IT8505195A0 (it) | 1985-07-01 |
NL192116B (nl) | 1996-10-01 |
JPS6115691A (ja) | 1986-01-23 |
NL8501880A (nl) | 1986-02-03 |
JP2554459B2 (ja) | 1996-11-13 |
AU599003B2 (en) | 1990-07-12 |
GB2162851B (en) | 1989-05-17 |
SE8503228D0 (sv) | 1985-06-28 |
CA1304023C (en) | 1992-06-23 |
GB8516591D0 (en) | 1985-08-07 |
NL192116C (nl) | 1997-02-04 |
FR2566799B1 (fr) | 1989-10-20 |
CH670654A5 (US06168655-20010102-C00055.png) | 1989-06-30 |
KR920009543B1 (ko) | 1992-10-19 |
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