DE3504748C2 - - Google Patents

Info

Publication number
DE3504748C2
DE3504748C2 DE3504748A DE3504748A DE3504748C2 DE 3504748 C2 DE3504748 C2 DE 3504748C2 DE 3504748 A DE3504748 A DE 3504748A DE 3504748 A DE3504748 A DE 3504748A DE 3504748 C2 DE3504748 C2 DE 3504748C2
Authority
DE
Germany
Prior art keywords
cells
medium
gas
cell
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3504748A
Other languages
German (de)
English (en)
Other versions
DE3504748A1 (de
Inventor
Randall G. Medfield Mass. Us Rupp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Biotech Inc
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Publication of DE3504748A1 publication Critical patent/DE3504748A1/de
Application granted granted Critical
Publication of DE3504748C2 publication Critical patent/DE3504748C2/de
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16Particles; Beads; Granular material; Encapsulation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06Nozzles; Sprayers; Spargers; Diffusers

Landscapes

  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE19853504748 1984-02-13 1985-02-12 Verfahren zur kultivierung von zellen in hoher dichte Granted DE3504748A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57949384A 1984-02-13 1984-02-13

Publications (2)

Publication Number Publication Date
DE3504748A1 DE3504748A1 (de) 1985-09-05
DE3504748C2 true DE3504748C2 (nl) 1987-07-23

Family

ID=24317121

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19853504748 Granted DE3504748A1 (de) 1984-02-13 1985-02-12 Verfahren zur kultivierung von zellen in hoher dichte

Country Status (11)

Country Link
JP (1) JPS60199380A (nl)
AU (1) AU572608B2 (nl)
BE (1) BE901702A (nl)
DE (1) DE3504748A1 (nl)
DK (1) DK65085A (nl)
FR (1) FR2559500A1 (nl)
GB (1) GB2154246B (nl)
IT (1) IT1184884B (nl)
NL (1) NL8500351A (nl)
NO (1) NO850534L (nl)
SE (1) SE8500622L (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3739650C1 (de) * 1987-11-23 1989-05-24 Immuno Ag Fermenter zum Zuechten von Zellkulturen

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724206A (en) * 1984-02-13 1988-02-09 Damon Biotech, Inc. Protein production using hypertonic media
US4829002A (en) * 1986-05-12 1989-05-09 Baxter International Inc. System for metering nutrient media to cell culture containers and method
EP0318487B1 (en) * 1986-08-04 1993-10-13 The University Of New South Wales Serum free tissue culture medium containing polymeric cell-protective agent
JPS6423888A (en) * 1987-07-16 1989-01-26 Etsuko Kakizaki Culture vessel with micro-cellular wall
JP2509630B2 (ja) * 1987-07-29 1996-06-26 三井石油化学工業株式会社 培養方法及び培養装置
WO2005035748A1 (en) 2003-10-10 2005-04-21 Novo Nordisk Health Care Ag Method for large-scale production of a polypeptide in eukaryote cells and a culture vessel suitable therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4409331A (en) * 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
US4724206A (en) * 1984-02-13 1988-02-09 Damon Biotech, Inc. Protein production using hypertonic media

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3739650C1 (de) * 1987-11-23 1989-05-24 Immuno Ag Fermenter zum Zuechten von Zellkulturen

Also Published As

Publication number Publication date
BE901702A (fr) 1985-05-29
FR2559500A1 (fr) 1985-08-16
NL8500351A (nl) 1985-09-02
IT8567141A0 (it) 1985-02-12
GB8503248D0 (en) 1985-03-13
NO850534L (no) 1985-08-14
AU572608B2 (en) 1988-05-12
IT8567141A1 (it) 1986-08-12
DE3504748A1 (de) 1985-09-05
SE8500622L (sv) 1985-08-14
IT1184884B (it) 1987-10-28
JPS6110115B2 (nl) 1986-03-28
SE8500622D0 (sv) 1985-02-12
GB2154246B (en) 1987-09-09
AU3857185A (en) 1985-08-22
DK65085A (da) 1985-08-14
GB2154246A (en) 1985-09-04
JPS60199380A (ja) 1985-10-08
DK65085D0 (da) 1985-02-12

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8363 Opposition against the patent
8330 Complete renunciation