BE901702A - Procede de culture de cellules avec barbotage d'un gaz. - Google Patents

Procede de culture de cellules avec barbotage d'un gaz.

Info

Publication number
BE901702A
BE901702A BE0/214491A BE214491A BE901702A BE 901702 A BE901702 A BE 901702A BE 0/214491 A BE0/214491 A BE 0/214491A BE 214491 A BE214491 A BE 214491A BE 901702 A BE901702 A BE 901702A
Authority
BE
Belgium
Prior art keywords
gas spring
culturing cells
cells
medium
gas
Prior art date
Application number
BE0/214491A
Other languages
English (en)
Inventor
R G Rupp
Original Assignee
Damon Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Damon Biotech Inc filed Critical Damon Biotech Inc
Publication of BE901702A publication Critical patent/BE901702A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02—Stirrer or mobile mixing elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers

Landscapes

  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Procédé de culture de cellules n'ayant pas de paroi, par lequel un gaz est introduit directement dans le milieu de culture (22) par une tete de barbotage (28), avec un débit suffisant pour que la concentration d'oxygène et d'anhydride carbonique reste constante dans le milieu. Les cellules sont encapsulées dans des membranes semiperméables qui les protègent contre les détériorations physiques. Application à la production de protéines et d'anticorps par des cultures cellulaires.
BE0/214491A 1984-02-13 1985-02-11 Procede de culture de cellules avec barbotage d'un gaz. BE901702A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57949384A 1984-02-13 1984-02-13

Publications (1)

Publication Number Publication Date
BE901702A true BE901702A (fr) 1985-05-29

Family

ID=24317121

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214491A BE901702A (fr) 1984-02-13 1985-02-11 Procede de culture de cellules avec barbotage d'un gaz.

Country Status (11)

Country Link
JP (1) JPS60199380A (fr)
AU (1) AU572608B2 (fr)
BE (1) BE901702A (fr)
DE (1) DE3504748A1 (fr)
DK (1) DK65085A (fr)
FR (1) FR2559500A1 (fr)
GB (1) GB2154246B (fr)
IT (1) IT1184884B (fr)
NL (1) NL8500351A (fr)
NO (1) NO850534L (fr)
SE (1) SE8500622L (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724206A (en) * 1984-02-13 1988-02-09 Damon Biotech, Inc. Protein production using hypertonic media
US4829002A (en) * 1986-05-12 1989-05-09 Baxter International Inc. System for metering nutrient media to cell culture containers and method
DE3787805T2 (de) * 1986-08-04 1994-02-10 Garvan Inst Med Res Serumfreies gewebekulturmedium, das ein polymerzellenschutzmittel enthält.
JPS6423888A (en) * 1987-07-16 1989-01-26 Etsuko Kakizaki Culture vessel with micro-cellular wall
JP2509630B2 (ja) * 1987-07-29 1996-06-26 三井石油化学工業株式会社 培養方法及び培養装置
DE3739650C1 (de) * 1987-11-23 1989-05-24 Immuno Ag Fermenter zum Zuechten von Zellkulturen
JP4740138B2 (ja) 2003-10-10 2011-08-03 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 真核生物細胞におけるポリペプチドの大規模生産方法及びそれに適した培養容器

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4352883A (en) * 1979-03-28 1982-10-05 Damon Corporation Encapsulation of biological material
US4409331A (en) * 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
US4724206A (en) * 1984-02-13 1988-02-09 Damon Biotech, Inc. Protein production using hypertonic media

Also Published As

Publication number Publication date
DK65085D0 (da) 1985-02-12
DK65085A (da) 1985-08-14
SE8500622L (sv) 1985-08-14
SE8500622D0 (sv) 1985-02-12
GB2154246B (en) 1987-09-09
NL8500351A (nl) 1985-09-02
GB2154246A (en) 1985-09-04
AU3857185A (en) 1985-08-22
DE3504748A1 (de) 1985-09-05
IT1184884B (it) 1987-10-28
JPS6110115B2 (fr) 1986-03-28
DE3504748C2 (fr) 1987-07-23
AU572608B2 (en) 1988-05-12
FR2559500A1 (fr) 1985-08-16
IT8567141A0 (it) 1985-02-12
GB8503248D0 (en) 1985-03-13
JPS60199380A (ja) 1985-10-08
IT8567141A1 (it) 1986-08-12
NO850534L (no) 1985-08-14

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: DAMON BIOTECH INC.

Effective date: 19890228