DE3479867D1 - A method of and an apparatus for analysing a liquid specimen using a binding assay - Google Patents

A method of and an apparatus for analysing a liquid specimen using a binding assay

Info

Publication number
DE3479867D1
DE3479867D1 DE8484301829T DE3479867T DE3479867D1 DE 3479867 D1 DE3479867 D1 DE 3479867D1 DE 8484301829 T DE8484301829 T DE 8484301829T DE 3479867 T DE3479867 T DE 3479867T DE 3479867 D1 DE3479867 D1 DE 3479867D1
Authority
DE
Germany
Prior art keywords
well
thread
coated
liquid specimen
elongated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8484301829T
Other languages
English (en)
Inventor
William J Sell
David H Riege
Vincent A Marinkovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Chemical Diagnostics Inc
Original Assignee
Mast Immunosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mast Immunosystems Inc filed Critical Mast Immunosystems Inc
Application granted granted Critical
Publication of DE3479867D1 publication Critical patent/DE3479867D1/de
Expired legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1048General features of the devices using the transfer device for another function
    • G01N2035/1062General features of the devices using the transfer device for another function for testing the liquid while it is in the transfer device

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
DE8484301829T 1983-03-17 1984-03-16 A method of and an apparatus for analysing a liquid specimen using a binding assay Expired DE3479867D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/476,367 US4567149A (en) 1983-03-17 1983-03-17 Binding assay system and method of making and using same

Publications (1)

Publication Number Publication Date
DE3479867D1 true DE3479867D1 (en) 1989-11-02

Family

ID=23891556

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484301829T Expired DE3479867D1 (en) 1983-03-17 1984-03-16 A method of and an apparatus for analysing a liquid specimen using a binding assay

Country Status (7)

Country Link
US (1) US4567149A (de)
EP (1) EP0119858B1 (de)
JP (1) JPH0617913B2 (de)
AT (1) ATE46628T1 (de)
AU (1) AU580952B2 (de)
CA (1) CA1231893A (de)
DE (1) DE3479867D1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2584498B1 (fr) * 1985-07-02 1987-10-16 Centre Nat Rech Scient Dispositif pour detecter sur une feuille de nitrocellulose la presence de complexes macromoleculaires, tels que antigenes/anticorps et procede de mise en oeuvre.
JPS6275265A (ja) * 1985-09-26 1987-04-07 東レ株式会社 免疫診断用プロ−ブ系および免疫診断方法
US4725406A (en) * 1985-10-21 1988-02-16 American Bionetics, Inc. Apparatus and method for diagnostic analysis of biological fluids
NL8600056A (nl) * 1986-01-13 1987-08-03 Nederlanden Staat Werkwijze voor het aantonen van een lid van een immunologisch paar, werkwijze voor het bereiden van een drager waaraan een lid van een immunologisch paar is gebonden alsmede analyse-inrichting geschikt voor het uitvoeren van dergelijke werkwijzen.
JPS63118654A (ja) * 1986-11-07 1988-05-23 Agency Of Ind Science & Technol 多項目イムノアツセイ装置
JPS63253255A (ja) * 1987-04-10 1988-10-20 Nippon Chemiphar Co Ltd アレルゲン検査具およびアレルゲン検査法
US5447837A (en) * 1987-08-05 1995-09-05 Calypte, Inc. Multi-immunoassay diagnostic system for antigens or antibodies or both
US5075077A (en) 1988-08-02 1991-12-24 Abbott Laboratories Test card for performing assays
US5320808A (en) * 1988-08-02 1994-06-14 Abbott Laboratories Reaction cartridge and carousel for biological sample analyzer
CA2035595A1 (en) * 1990-04-12 1991-10-13 Carol A. Miller Immunoassay test device with thread control element
SE9404166D0 (sv) * 1994-11-30 1994-11-30 Pharmacia Biotech Ab Multifunctional surfaces
AU6661296A (en) * 1996-08-16 1998-03-06 Oy Medix Biochemica Ab Coated flexible thread-like solid carrier for immunoassays
DE19721151C2 (de) * 1997-05-21 2002-10-31 Merck Patent Gmbh Streifentest zur in-vitro-Allergiediagnostik
US6908770B1 (en) 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
US7022517B1 (en) 1999-07-16 2006-04-04 Board Of Regents, The University Of Texas System Method and apparatus for the delivery of samples to a chemical sensor array
WO2001006244A2 (en) 1999-07-16 2001-01-25 Board Of Regents, The University Of Texas System General signaling protocols for chemical receptors in immobilized matrices
DE60135092D1 (de) 2000-01-31 2008-09-11 Univ Texas Tragbare vorrichtung mit einer sensor-array-anordnung
EP1447135B1 (de) * 2000-03-21 2007-01-03 Hitachi Chemical Diagnostics, Inc. Fluidisch verbesserte in-vitro-Diagnose-Prüfkammer
DE60120654T2 (de) * 2000-03-21 2007-05-31 Hitachi Chemical Diagnostics, Inc., Mountain View Optisch und fluidisch verbesserte in-vitro-diagnose-prüfkammer
AU2001268651A1 (en) * 2000-08-11 2002-02-25 Wisconsin Alumni Research Foundation. Chemical screening system using strip arrays
US20020168782A1 (en) * 2001-01-03 2002-11-14 Mccall Catherine A. Detection of allergen-specific IgE
CA2437558A1 (en) * 2001-01-31 2002-08-08 The Board Of Regents Of The University Of Texas System Method and apparatus for the confinement of materials in a micromachined chemical sensor array
US20020164808A1 (en) * 2001-05-03 2002-11-07 Hideki Itaya Diagnostic pipette assembly including apparatus for automated aspiration
WO2003086637A1 (en) * 2002-04-12 2003-10-23 Instrumentation Laboratory Company Immunoassay probe
US8257967B2 (en) * 2002-04-26 2012-09-04 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors
EP1590659A4 (de) * 2003-02-07 2010-04-21 Univ Texas Mehrschalen-microsphären mit integrierten chromatographischen und detektionsschichten zur verwendung in array-sensoren
EP1695082A2 (de) * 2003-12-11 2006-08-30 Board of Regents, The University of Texas System Verfahren und vorrichtung für die analyse von speichel unter verwendung eines sensorarrays
DE102004008319B4 (de) * 2004-02-17 2006-11-02 Hans-Knöll-Institut für Naturstoff-Forschung e.V. Kontinuierlich arbeitendes eindimensionales Festphasenreaktor-System
EP1564556A1 (de) * 2004-02-17 2005-08-17 DST Diagnostic Science & Technology GmbH Verfahren und Vorrichtung zur Bestimmung mehrerer Analyten mit simultaner interner Kontrolle
US8105849B2 (en) * 2004-02-27 2012-01-31 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements
US8101431B2 (en) * 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US8211386B2 (en) * 2004-06-08 2012-07-03 Biokit, S.A. Tapered cuvette and method of collecting magnetic particles
EP1910824A4 (de) 2005-05-31 2012-11-21 Labnow Inc Verfahren und zusammensetzungen in zusammenhang mit der erstellung und verwendung eines weissen blutbildes
CA2613078A1 (en) * 2005-06-24 2007-01-04 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
WO2007005666A2 (en) * 2005-07-01 2007-01-11 Board Of Regents, The University Of Texas System System and method of analyte detection using differential receptors
JP2008098484A (ja) * 2006-10-13 2008-04-24 Fine Steel Engineering:Kk 一体化積層体の製造方法および機械部品
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
JP4896664B2 (ja) * 2006-10-30 2012-03-14 三菱電機株式会社 回転電機用回転子
CA2697357A1 (en) * 2007-04-16 2008-10-30 John T. Mcdevitt Cardibioindex/cardibioscore and utility of salivary proteome in cardiovascular diagnostics
AU2009228014B2 (en) * 2008-03-27 2014-10-02 President And Fellows Of Harvard College Cotton thread as a low-cost multi-assay diagnostic platform
KR20100128340A (ko) * 2008-03-27 2010-12-07 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 종이 기반 마이크로유체 시스템

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3925116A (en) * 1972-08-09 1975-12-09 Niels N Engel Superhard martensite and method of making the same
ZA733612B (en) * 1972-10-11 1974-04-24 Merck Patent Gmbh Container for test strips
US4031197A (en) * 1973-04-25 1977-06-21 Gte New Ventures Corporation In vitro method for determining allergic hypersensitivity
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
US4284725A (en) * 1976-08-13 1981-08-18 Dynasciences Corporation Virus titration and identification system
JPS54106089A (en) * 1978-02-08 1979-08-20 Kanegafuchi Chem Ind Co Ltd Production of fluorine-containing ion exchange membrane
US4230757A (en) * 1978-06-21 1980-10-28 Eastman Kodak Company Sonically securing articles in plastic mounts
US4323536A (en) * 1980-02-06 1982-04-06 Eastman Kodak Company Multi-analyte test device
US4459360A (en) * 1981-10-05 1984-07-10 Mast Medical Industries, Ltd. Multiple-component binding assay system and method of making and using it
US5073484A (en) * 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
US4459630A (en) * 1982-08-27 1984-07-10 Honeywell, Inc. Excess current protection circuit for a power supply

Also Published As

Publication number Publication date
US4567149A (en) 1986-01-28
AU2563384A (en) 1984-09-20
ATE46628T1 (de) 1989-10-15
EP0119858A3 (en) 1985-09-11
JPH0617913B2 (ja) 1994-03-09
AU580952B2 (en) 1989-02-09
EP0119858A2 (de) 1984-09-26
JPS6089753A (ja) 1985-05-20
CA1231893A (en) 1988-01-26
EP0119858B1 (de) 1989-09-27

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