DE3485653D1 - Verfahren und vorrichtung zur messung des reaktionsgrades zwischen antigenen und zell-leukozytenantikoerpern. - Google Patents

Verfahren und vorrichtung zur messung des reaktionsgrades zwischen antigenen und zell-leukozytenantikoerpern.

Info

Publication number
DE3485653D1
DE3485653D1 DE8484113101T DE3485653T DE3485653D1 DE 3485653 D1 DE3485653 D1 DE 3485653D1 DE 8484113101 T DE8484113101 T DE 8484113101T DE 3485653 T DE3485653 T DE 3485653T DE 3485653 D1 DE3485653 D1 DE 3485653D1
Authority
DE
Germany
Prior art keywords
reaction
degree
antigen
measuring
computer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484113101T
Other languages
English (en)
Inventor
Mark J Pasula
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amtl Corp (nd Ges D Staates Delaware) Hollyw
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE3485653D1 publication Critical patent/DE3485653D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE8484113101T 1983-11-01 1984-10-31 Verfahren und vorrichtung zur messung des reaktionsgrades zwischen antigenen und zell-leukozytenantikoerpern. Expired - Lifetime DE3485653D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/547,767 US4614722A (en) 1983-11-01 1983-11-01 Method and apparatus for measuring the degree of reaction between antigens and leukocyte cellular antibodies

Publications (1)

Publication Number Publication Date
DE3485653D1 true DE3485653D1 (de) 1992-05-21

Family

ID=24186042

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484113101T Expired - Lifetime DE3485653D1 (de) 1983-11-01 1984-10-31 Verfahren und vorrichtung zur messung des reaktionsgrades zwischen antigenen und zell-leukozytenantikoerpern.

Country Status (6)

Country Link
US (1) US4614722A (de)
EP (1) EP0140379B1 (de)
JP (1) JPH061272B2 (de)
AT (1) ATE75041T1 (de)
CA (1) CA1248019A (de)
DE (1) DE3485653D1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5147785A (en) * 1983-11-01 1992-09-15 Amtl Corporation Method and apparatus for measuring the degree of reaction between a foreign entity and white blood cells
US4788155A (en) * 1983-11-01 1988-11-29 Pasula Mark J Method and apparatus for measuring the degree of reaction between a foreign entity and a subject's blood cells
DE3541033A1 (de) * 1985-11-19 1987-05-21 Boehringer Mannheim Gmbh Verfahren zur quantifizierung von zellpopulationen bzw. subpopulationen sowie hierfuer geeignetes reagenz
US4778750A (en) * 1986-02-19 1988-10-18 Imreg, Inc. Diagnostic methods for immune function
EP0281626B1 (de) * 1986-08-28 1996-06-05 Amtl Corporation Verfahren und vorrichtung zur feststellung des reaktionsgrades zwischen einem fremdkörper und den blutzellen eines patienten
JPH0246298A (ja) * 1988-06-23 1990-02-15 Atomic Energy Canada Ltd 潜在的毒性の試剤に対する有機体の感性の決定法
AT392481B (de) * 1989-04-18 1991-04-10 Keplinger Klaus Verfahren zum nachweis fuer die anwesenheit von aids-viren im menschlichen organismus
IE904616A1 (en) * 1989-12-20 1991-07-17 Pasula Mark J Kit for use in diagnosing maladies
WO1992001934A1 (en) * 1990-07-17 1992-02-06 Pasula Mark J Blood testing apparatus
SE467498B (sv) * 1990-11-20 1992-07-27 Vera Stejskal Foerfarande foer in vitro analys av kvicksilverallergier
GB9211902D0 (en) * 1992-06-05 1992-07-15 Food Tolerance Testing Ltd Method of determining the allergenic response of a sample of mammalian blood to an antigen
US5846758A (en) * 1995-11-30 1998-12-08 His Excellency Ghassan I. Shaker Method for diagnosing autoimmune diseases
US20090181078A1 (en) * 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
EP2468300B1 (de) 2006-09-26 2017-12-20 Infectious Disease Research Institute Impfstoffzusammensetzung mit einem synthetischen Adjuvans
EP2137297A4 (de) * 2007-04-11 2010-04-14 Roger Deutsch Verfahhren zur diagnostizierung biologischer proben mit stammzellen
CN102481312B (zh) 2009-06-05 2015-07-15 传染性疾病研究院 合成的吡喃葡萄糖脂佐剂
US9005915B2 (en) 2010-04-06 2015-04-14 Oxford Biomedical Technologies, Inc. Method for in vitro blood testing
EA027236B1 (ru) 2011-04-08 2017-07-31 Иммьюн Дизайн Корп. Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа
ES2729967T3 (es) 2012-02-07 2019-11-07 Infectious Disease Res Inst Formulaciones de adyuvante mejoradas que comprenden agonistas de TLR4 y métodos para usar las mismas
EP3388835B1 (de) 2012-05-16 2020-04-01 Immune Design Corp. Impfstoffe gegen hsv-2
CN105209047B (zh) 2013-04-18 2020-08-18 免疫设计股份有限公司 用于癌症治疗的gla单一疗法
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
US11801223B2 (en) 2013-12-31 2023-10-31 Access To Advanced Health Institute Single vial vaccine formulations
MX2018014399A (es) 2016-06-01 2019-06-06 Infectious Disease Res Inst Particulas de nanoalumbre que contienen un agente de dimensionamiento.
CN109738348A (zh) * 2019-01-28 2019-05-10 大连医科大学 基于颗粒计数的免疫凝集反应强度定量分析方法
CA3141577A1 (en) 2019-05-25 2020-12-03 Infectious Disease Research Institute Composition and method for spray drying an adjuvant vaccine emulsion

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH518730A (fr) * 1963-12-12 1972-02-15 Coulter Electronics Procédé de mélange d'un liquide et appareil pour la mise en oeuvre de ce procédé
BE790042A (nl) * 1971-10-14 1973-04-13 Coulter Electronics Werkwijze voor het classifiseren van deeltjes
US3949198A (en) * 1972-03-27 1976-04-06 Coulter Electronics, Inc. Methods and apparatuses for correcting coincidence count inaccuracies in a coulter type of particle analyzer
US4294817A (en) * 1977-11-25 1981-10-13 International Diagnostic Technology, Inc. Method of fluoro immunoassay
US4236893A (en) * 1979-04-09 1980-12-02 Minnesota Mining And Manufacturing Company Method for the assay of classes of antigen-specific antibodies
US4286963A (en) * 1979-11-23 1981-09-01 Coulter Electronics, Inc. Differential lymphoid-myeloid determination of leukocytes in whole blood
US4309184A (en) * 1980-05-08 1982-01-05 Majid Ali Method of determining food or chemical allergy and intolerance
US4346018A (en) * 1980-06-16 1982-08-24 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4374644A (en) * 1981-04-06 1983-02-22 Coulter Electronics, Inc. Blood cell volume monitoring
FR2530028A2 (fr) * 1982-07-09 1984-01-13 Pasteur Institut Nouveau reactif de diagnostic des parasitoses et des allergies, procede de preparation de ce nouveau reactif et procede de diagnostic des parasitoses et des allergies a l'aide dudit reactif
US4485175A (en) * 1983-01-03 1984-11-27 Coulter Electronics, Inc. Method for three-volume differential determination of lymphocyte, monocyte and granulocyte populations of leukocytes

Also Published As

Publication number Publication date
US4614722A (en) 1986-09-30
EP0140379B1 (de) 1992-04-15
CA1248019A (en) 1989-01-03
ATE75041T1 (de) 1992-05-15
EP0140379A2 (de) 1985-05-08
JPH061272B2 (ja) 1994-01-05
EP0140379A3 (en) 1986-03-12
JPS60155971A (ja) 1985-08-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AMTL CORP. (N.D. GES. D. STAATES DELAWARE), HOLLYW

8381 Inventor (new situation)

Free format text: PASULA, MARK J., MIAMI, FLA., US

8339 Ceased/non-payment of the annual fee