DE3419076A1 - Neues antitumor-antibiotikum 81-484 und seine herstellung - Google Patents

Neues antitumor-antibiotikum 81-484 und seine herstellung

Info

Publication number
DE3419076A1
DE3419076A1 DE19843419076 DE3419076A DE3419076A1 DE 3419076 A1 DE3419076 A1 DE 3419076A1 DE 19843419076 DE19843419076 DE 19843419076 DE 3419076 A DE3419076 A DE 3419076A DE 3419076 A1 DE3419076 A1 DE 3419076A1
Authority
DE
Germany
Prior art keywords
antibiotic
methanol
salt
spectrum
streptomyces
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19843419076
Other languages
German (de)
English (en)
Other versions
DE3419076C2 (https=
Inventor
Kanki Yokohama Komiyama
Iwao Tokio/Tokyo Umezawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Publication of DE3419076A1 publication Critical patent/DE3419076A1/de
Application granted granted Critical
Publication of DE3419076C2 publication Critical patent/DE3419076C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE19843419076 1983-12-28 1984-05-22 Neues antitumor-antibiotikum 81-484 und seine herstellung Granted DE3419076A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58245572A JPS60141293A (ja) 1983-12-28 1983-12-28 新規制癌性抗生物質８１−４８４およびその製造法

Publications (2)

Publication Number Publication Date
DE3419076A1 true DE3419076A1 (de) 1985-07-11
DE3419076C2 DE3419076C2 (https=) 1987-08-20

Family

ID=17135710

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843419076 Granted DE3419076A1 (de) 1983-12-28 1984-05-22 Neues antitumor-antibiotikum 81-484 und seine herstellung

Country Status (5)

Country Link
US (1) US4550021A (https=)
JP (1) JPS60141293A (https=)
DE (1) DE3419076A1 (https=)
FR (1) FR2557455B1 (https=)
GB (2) GB2152028B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918100A (en) * 1983-09-12 1990-04-17 Warner-Lambert Company CL-1957B antibiotic compound and its production

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7288396B2 (en) * 2003-09-11 2007-10-30 Kosan Biosciences Incorporated Biosynthetic gene cluster for leptomycins
US7876061B2 (en) * 2007-06-01 2011-01-25 Progress Rail Services Corp. Power system with multiple generator units
US7952306B2 (en) * 2007-06-01 2011-05-31 Progress Rail Services Corp Power system with multiple generator units
CN103789221B (zh) * 2013-04-28 2016-05-04 北京农学院 具有广谱抑菌活性的放线菌及其筛选方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0139457A2 (en) * 1983-09-12 1985-05-02 Warner-Lambert Company An antibiotic compound and its production

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (https=) * 1972-06-08 1974-02-08
ZW13679A1 (en) * 1978-08-03 1981-02-18 Ici Ltd Streptomyces metabolite
JPS5632481A (en) * 1979-08-23 1981-04-01 Sankyo Co Ltd Antibiotic b-41d, its preparation, and acaricide and anthelminthic agent and repellent containing the same as active constituent
US4283390A (en) * 1979-11-01 1981-08-11 Eli Lilly And Company Antibiotics and process for production thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0139457A2 (en) * 1983-09-12 1985-05-02 Warner-Lambert Company An antibiotic compound and its production

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J. Antibiotics, Bd. 38, Nr. 7, Juli 1985, Index 85-105 *
The Journal of Antibiotics, April 1985, S. 460 ff. *
The Journal of Antibiotics, Bd. 38, Nr. 2, S. 220-222 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918100A (en) * 1983-09-12 1990-04-17 Warner-Lambert Company CL-1957B antibiotic compound and its production

Also Published As

Publication number Publication date
GB2188624B (en) 1988-07-13
DE3419076C2 (https=) 1987-08-20
JPS60141293A (ja) 1985-07-26
US4550021A (en) 1985-10-29
GB2152028B (en) 1988-09-28
FR2557455B1 (fr) 1987-08-21
GB2188624A (en) 1987-10-07
FR2557455A1 (fr) 1985-07-05
GB8412289D0 (en) 1984-06-20
GB8710389D0 (en) 1987-06-03
GB2152028A (en) 1985-07-31

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee