DE3403922A1 - Mitomycin-analoge verbindungen - Google Patents

Mitomycin-analoge verbindungen

Info

Publication number
DE3403922A1
DE3403922A1 DE19843403922 DE3403922A DE3403922A1 DE 3403922 A1 DE3403922 A1 DE 3403922A1 DE 19843403922 DE19843403922 DE 19843403922 DE 3403922 A DE3403922 A DE 3403922A DE 3403922 A1 DE3403922 A1 DE 3403922A1
Authority
DE
Germany
Prior art keywords
methoxy
methyl
hexahydro
azirino
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19843403922
Other languages
German (de)
English (en)
Inventor
William A. Tucson Ariz. Remers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University Patents Inc
Original Assignee
University Patents Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Patents Inc filed Critical University Patents Inc
Publication of DE3403922A1 publication Critical patent/DE3403922A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19843403922 1983-02-07 1984-02-04 Mitomycin-analoge verbindungen Withdrawn DE3403922A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46461283A 1983-02-07 1983-02-07

Publications (1)

Publication Number Publication Date
DE3403922A1 true DE3403922A1 (de) 1984-08-09

Family

ID=23844605

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843403922 Withdrawn DE3403922A1 (de) 1983-02-07 1984-02-04 Mitomycin-analoge verbindungen

Country Status (29)

Country Link
JP (1) JPS59152384A (sv)
KR (1) KR900006854B1 (sv)
AT (1) AT385509B (sv)
AU (1) AU571193B2 (sv)
BE (1) BE898856A (sv)
CA (1) CA1252789A (sv)
CH (1) CH658658A5 (sv)
DD (1) DD233844A5 (sv)
DE (1) DE3403922A1 (sv)
DK (1) DK161890C (sv)
ES (1) ES8607305A1 (sv)
FI (1) FI80698C (sv)
FR (1) FR2540500B1 (sv)
GB (1) GB2134514B (sv)
GR (1) GR81455B (sv)
HU (1) HU190236B (sv)
IE (1) IE56814B1 (sv)
IL (1) IL70897A (sv)
IT (1) IT1178855B (sv)
LU (1) LU85199A1 (sv)
NL (1) NL8400338A (sv)
NO (1) NO161374C (sv)
NZ (1) NZ206932A (sv)
OA (1) OA07654A (sv)
PH (1) PH20249A (sv)
PT (1) PT78067B (sv)
SE (1) SE461982B (sv)
YU (1) YU44984B (sv)
ZA (1) ZA84788B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
CA1282069C (en) * 1985-09-12 1991-03-26 Damon L. Meyer Antibody complexes of hapten-modified diagnostic or therapeutic agents
JPS63150282A (ja) * 1986-12-13 1988-06-22 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS63246379A (ja) * 1987-03-31 1988-10-13 Kyowa Hakko Kogyo Co Ltd 7−n,8−n−エチレンマイトマイシン8−イミン類
EP0485904B1 (en) * 1990-11-13 1997-08-20 Kyowa Hakko Kogyo Co., Ltd. Mitomycin derivatives

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
DE3217769A1 (de) * 1981-05-15 1982-12-09 University Patents, Inc., 6851 Norwalk, Conn. Mitomycon-analoge verbindungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
JPS5686184A (en) * 1979-12-17 1981-07-13 Kyowa Hakko Kogyo Co Ltd Novel mitomycin c derivative
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
DE3217769A1 (de) * 1981-05-15 1982-12-09 University Patents, Inc., 6851 Norwalk, Conn. Mitomycon-analoge verbindungen

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Gann 71(1980), 560-562 *
J. Meed. Chem. 26(1), 1983, 16-20 *

Also Published As

Publication number Publication date
GB2134514A (en) 1984-08-15
NL8400338A (nl) 1984-09-03
SE8400628L (sv) 1984-08-08
FI80698C (sv) 1990-07-10
FI840502A (fi) 1984-08-08
IL70897A0 (en) 1984-05-31
SE461982B (sv) 1990-04-23
AT385509B (de) 1988-04-11
IE56814B1 (en) 1991-12-18
FI80698B (fi) 1990-03-30
DK161890B (da) 1991-08-26
DK52484A (da) 1984-08-08
IE840272L (en) 1984-08-07
IT8467113A0 (it) 1984-02-07
YU44984B (en) 1991-06-30
SE8400628D0 (sv) 1984-02-07
ATA37684A (de) 1987-09-15
CA1252789A (en) 1989-04-18
GB2134514B (en) 1987-04-01
YU21784A (en) 1986-10-31
ES529478A0 (es) 1986-05-16
NO161374B (no) 1989-05-02
GR81455B (sv) 1984-12-11
FI840502A0 (fi) 1984-02-07
ZA84788B (en) 1984-09-26
DK161890C (da) 1992-02-03
DK52484D0 (da) 1984-02-06
DD233844A5 (de) 1986-03-12
IL70897A (en) 1989-01-31
NO161374C (no) 1989-08-09
NO840433L (no) 1984-08-08
FR2540500B1 (fr) 1987-07-17
JPS59152384A (ja) 1984-08-31
AU571193B2 (en) 1988-04-14
FR2540500A1 (fr) 1984-08-10
CH658658A5 (de) 1986-11-28
PT78067A (en) 1984-03-01
NZ206932A (en) 1987-08-31
OA07654A (fr) 1985-05-23
HU190236B (en) 1986-08-28
PH20249A (en) 1986-11-10
AU2407384A (en) 1984-08-16
PT78067B (en) 1986-03-20
BE898856A (fr) 1984-05-30
KR840007726A (ko) 1984-12-10
IT1178855B (it) 1987-09-16
GB8402233D0 (en) 1984-02-29
KR900006854B1 (ko) 1990-09-22
LU85199A1 (fr) 1984-05-30
ES8607305A1 (es) 1986-05-16

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8130 Withdrawal