DE3377797D1 - 2-quinolone derivatives - Google Patents

2-quinolone derivatives

Info

Publication number
DE3377797D1
DE3377797D1 DE8383401198T DE3377797T DE3377797D1 DE 3377797 D1 DE3377797 D1 DE 3377797D1 DE 8383401198 T DE8383401198 T DE 8383401198T DE 3377797 T DE3377797 T DE 3377797T DE 3377797 D1 DE3377797 D1 DE 3377797D1
Authority
DE
Germany
Prior art keywords
quinolone derivatives
quinolone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383401198T
Other languages
English (en)
Inventor
Hiroshi Enomoto
Tadatoshi Nomura
Yoshiaki Aoyagi
Shoichi Chokai
Tatsuhiko Kono
Masao Murase
Kichiro Inoue
Masahiro Adachi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Application granted granted Critical
Publication of DE3377797D1 publication Critical patent/DE3377797D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
DE8383401198T 1982-06-21 1983-06-10 2-quinolone derivatives Expired DE3377797D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57107366A JPS58225065A (ja) 1982-06-21 1982-06-21 ２−キノロン誘導体

Publications (1)

Publication Number Publication Date
DE3377797D1 true DE3377797D1 (en) 1988-09-29

Family

ID=14457260

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383401198T Expired DE3377797D1 (en) 1982-06-21 1983-06-10 2-quinolone derivatives

Country Status (7)

Country Link
US (1) US4526894A (de)
EP (1) EP0101330B1 (de)
JP (1) JPS58225065A (de)
KR (1) KR900004041B1 (de)
CA (1) CA1191140A (de)
DE (1) DE3377797D1 (de)
ES (4) ES8504130A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5916878A (ja) * 1982-07-20 1984-01-28 Mitsubishi Yuka Yakuhin Kk ２，４−ジヒドロキシ−３−アセチルキノリン類の製造方法
CA2091172C (en) * 1990-09-07 1997-05-20 Adriano Afonso Antiviral compounds and antihypertensive compounds
CA2091173A1 (en) * 1990-09-07 1992-03-08 Adriano Afonso Antiviral compounds and antihypertensive compounds
US5179107A (en) * 1990-09-07 1993-01-12 Schering Corporation Antiviral quinolinone compounds
US5179093A (en) * 1991-05-10 1993-01-12 Schering Corporation Quinoline-diones
JP2943725B2 (ja) * 1996-01-17 1999-08-30 大日本インキ化学工業株式会社 キノリノン誘導体及びそれを有効成分とする抗アレルギー剤
KR100908418B1 (ko) 2001-06-20 2009-07-21 액티버스 파마 컴퍼니 리미티드 퀴놀리논 유도체 의약 조성물 및 그의 제조 방법
GB0519969D0 (en) * 2005-09-30 2005-11-09 Argenta Discovery Ltd Quinoline compounds
DK1928457T3 (da) * 2005-09-30 2013-02-04 Pulmagen Therapeutics Asthma Ltd Quinoliner og deres terapeutiske anvendelse
PT2139881E (pt) * 2007-04-04 2012-01-17 Pulmagen Therapeutics Asthma Ltd Quinolinas e a sua utilização terapêutica
ES2625817T3 (es) * 2008-08-06 2017-07-20 Medivation Technologies, Inc. Inhibidores de tipo Dihidropiridoftalazinona de poli(ADP-ribosa)polimerasa (PARP)
JP5883397B2 (ja) 2010-02-03 2016-03-15 ビオマリン プハルマセウトイカル インコーポレイテッド Ｐｔｅｎ欠損に関連した疾患の治療におけるポリ（ａｄｐリボース）ポリメラーゼ（ｐａｒｐ）のジヒドロピリドフタラジノン阻害剤の使用
KR101826652B1 (ko) 2010-02-08 2018-02-07 메디베이션 테크놀로지즈, 인크. 디히드로피리도프탈라지논 유도체의 합성 방법
TWI557123B (zh) 2010-10-21 2016-11-11 梅迪維新技術公司 結晶型（８Ｓ，９Ｒ）－５－氟－８－（４－氟苯基）－９－（１－甲基－１Ｈ－１，２，４－三唑－５－基）－８，９－二氫－２Ｈ－吡啶并［４，３，２－ｄｅ］呔－３（７Ｈ）－酮甲苯磺酸鹽
CN102146068A (zh) * 2011-01-20 2011-08-10 南开大学 3-苯甲酰基-4-羟基香豆素衍生物及其类似物与在除草方面的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770480B2 (de) * 1968-05-22 1977-09-29 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2,4- dihydroxychinolin
CH606285A5 (de) * 1974-12-17 1978-10-31 Ciba Geigy Ag
US4086349A (en) * 1975-07-30 1978-04-25 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma
DE2806879A1 (de) * 1978-02-17 1979-08-23 Sandoz Ag 4-hydroxy-2-chinolinon-3-carbonsaeure- esterderivate
EP0062001B1 (de) * 1981-03-24 1987-05-27 Ciba-Geigy Ag Acyl-chinolinonderivate, Verfahren zu ihrer Herstellung, diese enthaltende pharmazeutische Präparate und ihre Verwendung

Also Published As

Publication number Publication date
KR840005101A (ko) 1984-11-03
EP0101330A2 (de) 1984-02-22
ES8504719A1 (es) 1985-05-01
ES8504723A1 (es) 1985-05-01
CA1191140A (en) 1985-07-30
US4526894A (en) 1985-07-02
JPH0249306B2 (de) 1990-10-29
EP0101330B1 (de) 1988-08-24
ES530393A0 (es) 1985-05-01
ES523419A0 (es) 1985-04-01
EP0101330A3 (en) 1984-08-22
ES8504130A1 (es) 1985-04-01
ES530391A0 (es) 1985-05-01
ES8504718A1 (es) 1985-05-01
ES530392A0 (es) 1985-05-01
KR900004041B1 (ko) 1990-06-09
JPS58225065A (ja) 1983-12-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee