GB8321880D0 - Desoxyuridine derivatives - Google Patents

Desoxyuridine derivatives

Info

Publication number
GB8321880D0
GB8321880D0 GB838321880A GB8321880A GB8321880D0 GB 8321880 D0 GB8321880 D0 GB 8321880D0 GB 838321880 A GB838321880 A GB 838321880A GB 8321880 A GB8321880 A GB 8321880A GB 8321880 D0 GB8321880 D0 GB 8321880D0
Authority
GB
United Kingdom
Prior art keywords
desoxyuridine
derivatives
desoxyuridine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB838321880A
Other versions
GB2125401B (en
GB2125401A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB8321880D0 publication Critical patent/GB8321880D0/en
Publication of GB2125401A publication Critical patent/GB2125401A/en
Application granted granted Critical
Publication of GB2125401B publication Critical patent/GB2125401B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
GB08321880A 1982-08-17 1983-08-15 Desoxyuridine derivatives and their use as pharmaceuticals Expired GB2125401B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH492282 1982-08-17

Publications (3)

Publication Number Publication Date
GB8321880D0 true GB8321880D0 (en) 1983-09-14
GB2125401A GB2125401A (en) 1984-03-07
GB2125401B GB2125401B (en) 1985-10-16

Family

ID=4284858

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08321880A Expired GB2125401B (en) 1982-08-17 1983-08-15 Desoxyuridine derivatives and their use as pharmaceuticals

Country Status (16)

Country Link
JP (1) JPS5953499A (en)
AU (1) AU1800483A (en)
BE (1) BE897516A (en)
DE (1) DE3390162T1 (en)
DK (1) DK372283A (en)
ES (1) ES8604943A1 (en)
FI (1) FI832884A (en)
FR (1) FR2531962B1 (en)
GB (1) GB2125401B (en)
IL (1) IL69497A0 (en)
IT (1) IT1169765B (en)
NL (1) NL8302859A (en)
PT (1) PT77209B (en)
SE (1) SE8304408L (en)
WO (1) WO1984000759A1 (en)
ZA (1) ZA836072B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
CA1295998C (en) * 1985-07-29 1992-02-18 Sai P. Sunkara Nucleosides and their use as antineoplastic agents
US5215971A (en) * 1986-12-19 1993-06-01 Medivir Ab Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
SE8605503D0 (en) * 1986-12-19 1986-12-19 Astra Laekemedel Ab NOVEL MEDICINAL USE
US5215970A (en) * 1987-04-16 1993-06-01 Medivir Ab Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
US4863927A (en) * 1987-05-11 1989-09-05 Merck & Co., Inc. 1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
US5606048A (en) * 1992-06-22 1997-02-25 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2', 2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5426183A (en) * 1992-06-22 1995-06-20 Eli Lilly And Company Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5371210A (en) * 1992-06-22 1994-12-06 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5594124A (en) * 1992-06-22 1997-01-14 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2',2'-difluoropyrimidine nucleosides and 2'-deoxy-2'-fluoropyrimidine nucleosides and intermediates thereof
US5821357A (en) * 1992-06-22 1998-10-13 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoropurine and triazole nucleosides
US5401838A (en) * 1992-06-22 1995-03-28 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
IL106078A0 (en) * 1992-06-22 1993-10-20 Lilly Co Eli Stereoselective anion glycosylation process
US5424416A (en) * 1993-08-25 1995-06-13 Eli Lilly And Company Process for preparation of 2-deoxy-2,2-difluoro-D-ribofuranosyl-3,5-hydroxy protected-1-alkyl and aryl sulfonates and their use in preparation of 2',2'-difluoro-2'-deoxy nucleosides
SE9701219D0 (en) * 1997-04-04 1997-04-04 Astra Pharma Prod New compounds
EP1425022A4 (en) * 2001-08-24 2009-04-29 Koronis Pharmaceuticals Inc Mutagenic nucleoside analogs for the treatment of viral disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709874A (en) * 1970-03-19 1973-01-09 Syntex Corp 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing
GB1601020A (en) * 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
GB2060604B (en) * 1979-10-03 1983-11-23 Univ Birmingham And Stichting E15-(2-halogenovinyl)-2'-deoxycytidines
DE3002197A1 (en) * 1980-01-22 1981-07-23 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen 5-Alkyl- and 5-alkenyl-uracil and -cytidine nucleoside derivs. - prepd. e.g. by reaction of 5'-chloro-5'-deoxy cpds. with ammonia
DE3010399A1 (en) * 1980-03-18 1981-09-24 Kailash Kumar Dr. 2359 Lentföhrden Gauri Cytostatic and antiviral pyrimidine nucleoside derivs. - which are 5-haloalkyl-pyrimidine nucleoside 5'-ester derivs.
HU183567B (en) * 1981-09-07 1984-05-28 Mta Koezponti Kemiai Kutato In Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof

Also Published As

Publication number Publication date
DE3390162T1 (en) 1985-02-21
DK372283A (en) 1984-02-18
JPS5953499A (en) 1984-03-28
BE897516A (en) 1984-02-13
ES8604943A1 (en) 1986-02-16
ES524997A0 (en) 1986-02-16
FR2531962A1 (en) 1984-02-24
NL8302859A (en) 1984-03-16
IT1169765B (en) 1987-06-03
FI832884A (en) 1984-02-18
WO1984000759A1 (en) 1984-03-01
IL69497A0 (en) 1983-11-30
DK372283D0 (en) 1983-08-15
GB2125401B (en) 1985-10-16
GB2125401A (en) 1984-03-07
SE8304408D0 (en) 1983-08-15
FI832884A0 (en) 1983-08-10
AU1800483A (en) 1984-02-23
PT77209A (en) 1983-09-01
IT8322565A0 (en) 1983-08-16
ZA836072B (en) 1985-03-27
SE8304408L (en) 1984-02-18
PT77209B (en) 1986-03-18
FR2531962B1 (en) 1986-11-14

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee