FR2531962B1 - NOVEL DESOXYURIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS - Google Patents

NOVEL DESOXYURIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

Info

Publication number
FR2531962B1
FR2531962B1 FR8313242A FR8313242A FR2531962B1 FR 2531962 B1 FR2531962 B1 FR 2531962B1 FR 8313242 A FR8313242 A FR 8313242A FR 8313242 A FR8313242 A FR 8313242A FR 2531962 B1 FR2531962 B1 FR 2531962B1
Authority
FR
France
Prior art keywords
desoxyuridine
medicaments
derivatives
novel
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8313242A
Other languages
French (fr)
Other versions
FR2531962A1 (en
Inventor
Herfried Griengl
Erich Wanek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2531962A1 publication Critical patent/FR2531962A1/en
Application granted granted Critical
Publication of FR2531962B1 publication Critical patent/FR2531962B1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR8313242A 1982-08-17 1983-08-10 NOVEL DESOXYURIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS Expired FR2531962B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH492282 1982-08-17

Publications (2)

Publication Number Publication Date
FR2531962A1 FR2531962A1 (en) 1984-02-24
FR2531962B1 true FR2531962B1 (en) 1986-11-14

Family

ID=4284858

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8313242A Expired FR2531962B1 (en) 1982-08-17 1983-08-10 NOVEL DESOXYURIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

Country Status (16)

Country Link
JP (1) JPS5953499A (en)
AU (1) AU1800483A (en)
BE (1) BE897516A (en)
DE (1) DE3390162T1 (en)
DK (1) DK372283A (en)
ES (1) ES8604943A1 (en)
FI (1) FI832884A (en)
FR (1) FR2531962B1 (en)
GB (1) GB2125401B (en)
IL (1) IL69497A0 (en)
IT (1) IT1169765B (en)
NL (1) NL8302859A (en)
PT (1) PT77209B (en)
SE (1) SE8304408L (en)
WO (1) WO1984000759A1 (en)
ZA (1) ZA836072B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
CA1295998C (en) * 1985-07-29 1992-02-18 Sai P. Sunkara Nucleosides and their use as antineoplastic agents
SE8605503D0 (en) * 1986-12-19 1986-12-19 Astra Laekemedel Ab NOVEL MEDICINAL USE
US5215971A (en) * 1986-12-19 1993-06-01 Medivir Ab Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
US5215970A (en) * 1987-04-16 1993-06-01 Medivir Ab Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
US4863927A (en) * 1987-05-11 1989-09-05 Merck & Co., Inc. 1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
FI932871A (en) * 1992-06-22 1993-12-23 Lilly Co Eli STEREOSELECTIVE ANJONGLYKOSYLATIONSPROCESS
US5371210A (en) * 1992-06-22 1994-12-06 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5821357A (en) * 1992-06-22 1998-10-13 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoropurine and triazole nucleosides
US5401838A (en) * 1992-06-22 1995-03-28 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5426183A (en) * 1992-06-22 1995-06-20 Eli Lilly And Company Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5606048A (en) * 1992-06-22 1997-02-25 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2', 2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5594124A (en) * 1992-06-22 1997-01-14 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2',2'-difluoropyrimidine nucleosides and 2'-deoxy-2'-fluoropyrimidine nucleosides and intermediates thereof
US5424416A (en) * 1993-08-25 1995-06-13 Eli Lilly And Company Process for preparation of 2-deoxy-2,2-difluoro-D-ribofuranosyl-3,5-hydroxy protected-1-alkyl and aryl sulfonates and their use in preparation of 2',2'-difluoro-2'-deoxy nucleosides
SE9701219D0 (en) * 1997-04-04 1997-04-04 Astra Pharma Prod New compounds
WO2003018030A1 (en) * 2001-08-24 2003-03-06 Koronis Pharmaceuticals, Inc. Mutagenic nucleoside analogs for the treatment of viral disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709874A (en) * 1970-03-19 1973-01-09 Syntex Corp 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing
GB1601020A (en) * 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
GB2060604B (en) * 1979-10-03 1983-11-23 Univ Birmingham And Stichting E15-(2-halogenovinyl)-2'-deoxycytidines
DE3002197A1 (en) * 1980-01-22 1981-07-23 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen 5-Alkyl- and 5-alkenyl-uracil and -cytidine nucleoside derivs. - prepd. e.g. by reaction of 5'-chloro-5'-deoxy cpds. with ammonia
DE3010399A1 (en) * 1980-03-18 1981-09-24 Kailash Kumar Dr. 2359 Lentföhrden Gauri Cytostatic and antiviral pyrimidine nucleoside derivs. - which are 5-haloalkyl-pyrimidine nucleoside 5'-ester derivs.
HU183567B (en) * 1981-09-07 1984-05-28 Mta Koezponti Kemiai Kutato In Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof

Also Published As

Publication number Publication date
GB2125401B (en) 1985-10-16
FI832884A (en) 1984-02-18
AU1800483A (en) 1984-02-23
GB2125401A (en) 1984-03-07
IL69497A0 (en) 1983-11-30
ES524997A0 (en) 1986-02-16
GB8321880D0 (en) 1983-09-14
JPS5953499A (en) 1984-03-28
DE3390162T1 (en) 1985-02-21
PT77209B (en) 1986-03-18
IT8322565A0 (en) 1983-08-16
FR2531962A1 (en) 1984-02-24
IT1169765B (en) 1987-06-03
DK372283D0 (en) 1983-08-15
FI832884A0 (en) 1983-08-10
PT77209A (en) 1983-09-01
BE897516A (en) 1984-02-13
NL8302859A (en) 1984-03-16
SE8304408D0 (en) 1983-08-15
ZA836072B (en) 1985-03-27
ES8604943A1 (en) 1986-02-16
DK372283A (en) 1984-02-18
SE8304408L (en) 1984-02-18
WO1984000759A1 (en) 1984-03-01

Similar Documents

Publication Publication Date Title
FR2531083B1 (en) NOVEL PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES
FR2535321B1 (en) NOVEL ETHANOL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES
FR2542000B1 (en) NOVEL ETHANOL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES
FR2615191B1 (en) NOVEL BENZO (B) PYRANS AND PYRANNOPYRIDINES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2561651B1 (en) NOVEL CYCLOSPORIN DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2551064B1 (en) NOVEL AROMATIC ESTERS AND AMIDES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2501199B1 (en) NOVEL POLYPEPTIDES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
FR2629825B1 (en) NOVEL PEPTIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2590902B1 (en) NOVEL CALCITONIN DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2531962B1 (en) NOVEL DESOXYURIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2511003B1 (en) ERGOPEPTIDE ALACALOIDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2559150B1 (en) NOVEL CYANO-2 BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES
FR2551438B1 (en) NOVEL ETHANOL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES
FR2496103B1 (en) NOVEL BENZOPYRAN AND BENZOTHIOPYRANE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
FR2540112B1 (en) NOVEL BENZO (G) QUINOLEIN DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
BE896590A (en) NOVEL AZEPINO-INDOLES, THEIR PREPARATION AND THEIR USE AS MEDICINES
FR2527608B1 (en) NOVEL HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2527206B1 (en) NOVEL 2 (1H) -PYRIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2596051B1 (en) NOVEL PURINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2549058B1 (en) NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2528431B1 (en) NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2536072B1 (en) NEW QUINAZOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS
FR2532308B1 (en) NOVEL POLYPEPTIDES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
BE878442A (en) N-PHENYL-INDOLIN DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS
FR2530634B1 (en) CARBAPENEMIC DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES

Legal Events

Date Code Title Description
ST Notification of lapse