PT77209B - Process for the preparation of deoxy uridine derivatives and of pharmaceutical compositions containing them - Google Patents

Process for the preparation of deoxy uridine derivatives and of pharmaceutical compositions containing them

Info

Publication number
PT77209B
PT77209B PT77209A PT7720983A PT77209B PT 77209 B PT77209 B PT 77209B PT 77209 A PT77209 A PT 77209A PT 7720983 A PT7720983 A PT 7720983A PT 77209 B PT77209 B PT 77209B
Authority
PT
Portugal
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
uridine derivatives
deoxy uridine
Prior art date
Application number
PT77209A
Other languages
Portuguese (pt)
Other versions
PT77209A (en
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of PT77209A publication Critical patent/PT77209A/en
Publication of PT77209B publication Critical patent/PT77209B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
PT77209A 1982-08-17 1983-08-16 Process for the preparation of deoxy uridine derivatives and of pharmaceutical compositions containing them PT77209B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH492282 1982-08-17

Publications (2)

Publication Number Publication Date
PT77209A PT77209A (en) 1983-09-01
PT77209B true PT77209B (en) 1986-03-18

Family

ID=4284858

Family Applications (1)

Application Number Title Priority Date Filing Date
PT77209A PT77209B (en) 1982-08-17 1983-08-16 Process for the preparation of deoxy uridine derivatives and of pharmaceutical compositions containing them

Country Status (16)

Country Link
JP (1) JPS5953499A (en)
AU (1) AU1800483A (en)
BE (1) BE897516A (en)
DE (1) DE3390162T1 (en)
DK (1) DK372283A (en)
ES (1) ES8604943A1 (en)
FI (1) FI832884A (en)
FR (1) FR2531962B1 (en)
GB (1) GB2125401B (en)
IL (1) IL69497A0 (en)
IT (1) IT1169765B (en)
NL (1) NL8302859A (en)
PT (1) PT77209B (en)
SE (1) SE8304408L (en)
WO (1) WO1984000759A1 (en)
ZA (1) ZA836072B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526988A (en) * 1983-03-10 1985-07-02 Eli Lilly And Company Difluoro antivirals and intermediate therefor
CA1295998C (en) * 1985-07-29 1992-02-18 Sai P. Sunkara Nucleosides and their use as antineoplastic agents
US5215971A (en) * 1986-12-19 1993-06-01 Medivir Ab Antiviral pharmaceutical composition comprising 5-substituted pyrimidine nucleosides
SE8605503D0 (en) * 1986-12-19 1986-12-19 Astra Laekemedel Ab NOVEL MEDICINAL USE
US5215970A (en) * 1987-04-16 1993-06-01 Medivir Ab Nucleosides and nucleotide analogues, pharmaceutical composition and processes for the preparation of the compounds
US4863927A (en) * 1987-05-11 1989-09-05 Merck & Co., Inc. 1-(2-hydroxymethyl)cycloalkylmethyl)-5-substituted uracils
US5401838A (en) * 1992-06-22 1995-03-28 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5606048A (en) * 1992-06-22 1997-02-25 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2', 2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5371210A (en) * 1992-06-22 1994-12-06 Eli Lilly And Company Stereoselective fusion glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
JPH0673086A (en) * 1992-06-22 1994-03-15 Eli Lilly & Co Stereoselective anionic glycosylation
US5426183A (en) * 1992-06-22 1995-06-20 Eli Lilly And Company Catalytic stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoronucleosides and 2'-deoxy-2'-fluoronucleosides
US5594124A (en) * 1992-06-22 1997-01-14 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-Deoxy-2',2'-difluoropyrimidine nucleosides and 2'-deoxy-2'-fluoropyrimidine nucleosides and intermediates thereof
US5821357A (en) * 1992-06-22 1998-10-13 Eli Lilly And Company Stereoselective glycosylation process for preparing 2'-deoxy-2',2'-difluoropurine and triazole nucleosides
US5424416A (en) * 1993-08-25 1995-06-13 Eli Lilly And Company Process for preparation of 2-deoxy-2,2-difluoro-D-ribofuranosyl-3,5-hydroxy protected-1-alkyl and aryl sulfonates and their use in preparation of 2',2'-difluoro-2'-deoxy nucleosides
SE9701219D0 (en) * 1997-04-04 1997-04-04 Astra Pharma Prod New compounds
EP1425022A4 (en) * 2001-08-24 2009-04-29 Koronis Pharmaceuticals Inc Mutagenic nucleoside analogs for the treatment of viral disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3709874A (en) * 1970-03-19 1973-01-09 Syntex Corp 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing
GB1601020A (en) * 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
GB2060604B (en) * 1979-10-03 1983-11-23 Univ Birmingham And Stichting E15-(2-halogenovinyl)-2'-deoxycytidines
DE3002197A1 (en) * 1980-01-22 1981-07-23 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen 5-Alkyl- and 5-alkenyl-uracil and -cytidine nucleoside derivs. - prepd. e.g. by reaction of 5'-chloro-5'-deoxy cpds. with ammonia
DE3010399A1 (en) * 1980-03-18 1981-09-24 Kailash Kumar Dr. 2359 Lentföhrden Gauri Cytostatic and antiviral pyrimidine nucleoside derivs. - which are 5-haloalkyl-pyrimidine nucleoside 5'-ester derivs.
HU183567B (en) * 1981-09-07 1984-05-28 Mta Koezponti Kemiai Kutato In Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof

Also Published As

Publication number Publication date
ES8604943A1 (en) 1986-02-16
IT1169765B (en) 1987-06-03
GB2125401B (en) 1985-10-16
JPS5953499A (en) 1984-03-28
SE8304408L (en) 1984-02-18
ES524997A0 (en) 1986-02-16
GB8321880D0 (en) 1983-09-14
ZA836072B (en) 1985-03-27
AU1800483A (en) 1984-02-23
DK372283A (en) 1984-02-18
IT8322565A0 (en) 1983-08-16
IL69497A0 (en) 1983-11-30
FR2531962A1 (en) 1984-02-24
SE8304408D0 (en) 1983-08-15
NL8302859A (en) 1984-03-16
GB2125401A (en) 1984-03-07
WO1984000759A1 (en) 1984-03-01
FI832884A0 (en) 1983-08-10
FR2531962B1 (en) 1986-11-14
PT77209A (en) 1983-09-01
DE3390162T1 (en) 1985-02-21
DK372283D0 (en) 1983-08-15
FI832884A (en) 1984-02-18
BE897516A (en) 1984-02-13

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