BE896590A - NOVEL AZEPINO-INDOLES, THEIR PREPARATION AND THEIR USE AS MEDICINES - Google Patents

NOVEL AZEPINO-INDOLES, THEIR PREPARATION AND THEIR USE AS MEDICINES

Info

Publication number
BE896590A
BE896590A BE1/10774A BE1010774A BE896590A BE 896590 A BE896590 A BE 896590A BE 1/10774 A BE1/10774 A BE 1/10774A BE 1010774 A BE1010774 A BE 1010774A BE 896590 A BE896590 A BE 896590A
Authority
BE
Belgium
Prior art keywords
azepino
indoles
medicines
novel
preparation
Prior art date
Application number
BE1/10774A
Other languages
French (fr)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of BE896590A publication Critical patent/BE896590A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE1/10774A 1982-05-06 1983-04-28 NOVEL AZEPINO-INDOLES, THEIR PREPARATION AND THEIR USE AS MEDICINES BE896590A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2806/82A CH649553A5 (en) 1982-05-06 1982-05-06 AZEPINOINDOLS AND METHOD FOR THE PRODUCTION THEREOF.

Publications (1)

Publication Number Publication Date
BE896590A true BE896590A (en) 1983-10-28

Family

ID=4242007

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/10774A BE896590A (en) 1982-05-06 1983-04-28 NOVEL AZEPINO-INDOLES, THEIR PREPARATION AND THEIR USE AS MEDICINES

Country Status (17)

Country Link
JP (1) JPS58203993A (en)
AU (1) AU1425683A (en)
BE (1) BE896590A (en)
CH (1) CH649553A5 (en)
DE (1) DE3315467A1 (en)
DK (1) DK199883A (en)
ES (1) ES522008A0 (en)
FI (1) FI831475L (en)
FR (1) FR2526434A1 (en)
GB (1) GB2120662B (en)
HU (1) HU189275B (en)
IL (1) IL68576A0 (en)
IT (1) IT1197644B (en)
NL (1) NL8301552A (en)
PT (1) PT76632B (en)
SE (1) SE8302554L (en)
ZA (1) ZA833266B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193083B (en) * 1984-02-22 1987-08-28 Sandoz Ag Process for preparing diazepinoindole derivatives further pharmaceutical compositions containing such compounds
AU582564B2 (en) * 1985-02-20 1989-04-06 Sandoz Ltd. 2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
US6586421B2 (en) * 2000-09-20 2003-07-01 Pharmacia & Upjohn Company Substituted azepino[4,5b]indoline derivatives
MXPA04001203A (en) * 2001-08-08 2004-05-20 Pharmacia & Upjhon Company THERAPEUTIC 1H-PYRIDO[4,3-b]INDOLES.
AU2007207508B2 (en) * 2006-01-19 2011-08-18 Athersys, Inc. Thiophenyl and pyrrolyl azepines as serotonin 5-HT2c receptor ligands and uses thereof
JP5501251B2 (en) 2008-01-11 2014-05-21 アルバニー モレキュラー リサーチ, インコーポレイテッド (1-Azinone) substituted pyridoindoles as MCH antagonists
US9073925B2 (en) 2009-07-01 2015-07-07 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
WO2011003007A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2011003012A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
EP2448585B1 (en) 2009-07-01 2014-01-01 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
US8697700B2 (en) 2010-12-21 2014-04-15 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof
US8993765B2 (en) 2010-12-21 2015-03-31 Albany Molecular Research, Inc. Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12641T1 (en) * 1979-11-02 1985-04-15 Sandoz Ag AZEPININDOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
FI831475L (en) 1983-11-07
PT76632B (en) 1986-01-27
IT8348232A0 (en) 1983-05-06
GB8312159D0 (en) 1983-06-08
DE3315467A1 (en) 1983-11-17
IT1197644B (en) 1988-12-06
NL8301552A (en) 1983-12-01
GB2120662B (en) 1985-09-11
DK199883D0 (en) 1983-05-04
FI831475A0 (en) 1983-04-29
IL68576A0 (en) 1983-09-30
JPS58203993A (en) 1983-11-28
ES8502440A1 (en) 1985-01-01
AU1425683A (en) 1983-11-10
SE8302554L (en) 1983-11-07
FR2526434A1 (en) 1983-11-10
ZA833266B (en) 1984-12-24
GB2120662A (en) 1983-12-07
SE8302554D0 (en) 1983-05-04
PT76632A (en) 1983-06-01
HU189275B (en) 1986-06-30
ES522008A0 (en) 1985-01-01
CH649553A5 (en) 1985-05-31
DK199883A (en) 1983-11-07

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19860430