SE8302554D0 - NEW AZEPINOINDOLES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

NEW AZEPINOINDOLES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
SE8302554D0
SE8302554D0 SE8302554A SE8302554A SE8302554D0 SE 8302554 D0 SE8302554 D0 SE 8302554D0 SE 8302554 A SE8302554 A SE 8302554A SE 8302554 A SE8302554 A SE 8302554A SE 8302554 D0 SE8302554 D0 SE 8302554D0
Authority
SE
Sweden
Prior art keywords
azepinoindoles
new
production
pharmaceutical compositions
compositions containing
Prior art date
Application number
SE8302554A
Other languages
Swedish (sv)
Other versions
SE8302554L (en
Inventor
F Gadient
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8302554D0 publication Critical patent/SE8302554D0/en
Publication of SE8302554L publication Critical patent/SE8302554L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

An 1-alkyl-1,2,3,4,5,6- hexahydro-azepino[4,5-b]indole, or a pharmaceutically acceptable acid addition salt thereof is a useful anti- depressant and neuroleptic agent.
SE8302554A 1982-05-06 1983-05-04 NEW AZEPINO INDOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SE8302554L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2806/82A CH649553A5 (en) 1982-05-06 1982-05-06 AZEPINOINDOLS AND METHOD FOR THE PRODUCTION THEREOF.

Publications (2)

Publication Number Publication Date
SE8302554D0 true SE8302554D0 (en) 1983-05-04
SE8302554L SE8302554L (en) 1983-11-07

Family

ID=4242007

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8302554A SE8302554L (en) 1982-05-06 1983-05-04 NEW AZEPINO INDOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (17)

Country Link
JP (1) JPS58203993A (en)
AU (1) AU1425683A (en)
BE (1) BE896590A (en)
CH (1) CH649553A5 (en)
DE (1) DE3315467A1 (en)
DK (1) DK199883A (en)
ES (1) ES522008A0 (en)
FI (1) FI831475L (en)
FR (1) FR2526434A1 (en)
GB (1) GB2120662B (en)
HU (1) HU189275B (en)
IL (1) IL68576A0 (en)
IT (1) IT1197644B (en)
NL (1) NL8301552A (en)
PT (1) PT76632B (en)
SE (1) SE8302554L (en)
ZA (1) ZA833266B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8500370A (en) * 1984-02-22 1985-09-16 Sandoz Ag DIAZEPINOINDOLS, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM.
AU582564B2 (en) * 1985-02-20 1989-04-06 Sandoz Ltd. 2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
JP2004509894A (en) 2000-09-20 2004-04-02 ファルマシア・アンド・アップジョン・カンパニー Substituted azepino [4,5-b] indoline derivatives
BR0211608A (en) * 2001-08-08 2006-04-04 Upjohn Co 1h-pyrido [4,3-b] therapeutic indoles
MX2008009178A (en) * 2006-01-19 2008-12-05 Athersys Inc Thiophenyl and pyrrolyl azepines as serotonin 5-ht2c receptor ligands and uses thereof.
US8716308B2 (en) 2008-01-11 2014-05-06 Albany Molecular Research, Inc. (1-azinone)-substituted pyridoindoles
US8629158B2 (en) 2009-07-01 2014-01-14 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
US8637501B2 (en) 2009-07-01 2014-01-28 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof
US8618299B2 (en) 2009-07-01 2013-12-31 Albany Molecular Research, Inc. Azinone-substituted azapolycycle MCH-1 antagonists, methods of making, and use thereof
WO2011003021A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2012088124A2 (en) 2010-12-21 2012-06-28 Albany Molecular Research, Inc. Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof
US8697700B2 (en) 2010-12-21 2014-04-15 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12641T1 (en) * 1979-11-02 1985-04-15 Sandoz Ag AZEPININDOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
DK199883D0 (en) 1983-05-04
CH649553A5 (en) 1985-05-31
GB8312159D0 (en) 1983-06-08
GB2120662A (en) 1983-12-07
HU189275B (en) 1986-06-30
DE3315467A1 (en) 1983-11-17
DK199883A (en) 1983-11-07
AU1425683A (en) 1983-11-10
GB2120662B (en) 1985-09-11
FR2526434A1 (en) 1983-11-10
IT1197644B (en) 1988-12-06
NL8301552A (en) 1983-12-01
ES8502440A1 (en) 1985-01-01
IT8348232A0 (en) 1983-05-06
JPS58203993A (en) 1983-11-28
FI831475A0 (en) 1983-04-29
BE896590A (en) 1983-10-28
SE8302554L (en) 1983-11-07
IL68576A0 (en) 1983-09-30
FI831475L (en) 1983-11-07
PT76632B (en) 1986-01-27
ZA833266B (en) 1984-12-24
ES522008A0 (en) 1985-01-01
PT76632A (en) 1983-06-01

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