ZA833266B - New azepino indoles,their production and pharmaceutical compositions containing them - Google Patents

New azepino indoles,their production and pharmaceutical compositions containing them

Info

Publication number
ZA833266B
ZA833266B ZA833266A ZA833266A ZA833266B ZA 833266 B ZA833266 B ZA 833266B ZA 833266 A ZA833266 A ZA 833266A ZA 833266 A ZA833266 A ZA 833266A ZA 833266 B ZA833266 B ZA 833266B
Authority
ZA
South Africa
Prior art keywords
azepino
indoles
new
production
pharmaceutical compositions
Prior art date
Application number
ZA833266A
Inventor
Gadient Fulvio
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA833266B publication Critical patent/ZA833266B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA833266A 1982-05-06 1983-05-06 New azepino indoles,their production and pharmaceutical compositions containing them ZA833266B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH2806/82A CH649553A5 (en) 1982-05-06 1982-05-06 AZEPINOINDOLS AND METHOD FOR THE PRODUCTION THEREOF.

Publications (1)

Publication Number Publication Date
ZA833266B true ZA833266B (en) 1984-12-24

Family

ID=4242007

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA833266A ZA833266B (en) 1982-05-06 1983-05-06 New azepino indoles,their production and pharmaceutical compositions containing them

Country Status (17)

Country Link
JP (1) JPS58203993A (en)
AU (1) AU1425683A (en)
BE (1) BE896590A (en)
CH (1) CH649553A5 (en)
DE (1) DE3315467A1 (en)
DK (1) DK199883A (en)
ES (1) ES522008A0 (en)
FI (1) FI831475L (en)
FR (1) FR2526434A1 (en)
GB (1) GB2120662B (en)
HU (1) HU189275B (en)
IL (1) IL68576A0 (en)
IT (1) IT1197644B (en)
NL (1) NL8301552A (en)
PT (1) PT76632B (en)
SE (1) SE8302554L (en)
ZA (1) ZA833266B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193083B (en) * 1984-02-22 1987-08-28 Sandoz Ag Process for preparing diazepinoindole derivatives further pharmaceutical compositions containing such compounds
AU582564B2 (en) * 1985-02-20 1989-04-06 Sandoz Ltd. 2,3,4,5-tetrahydro-11-phenyl-1H-``1,4``diazepino``1,7-a`` indoles, their production and pharmaceutical compositions containing them
US6586421B2 (en) * 2000-09-20 2003-07-01 Pharmacia & Upjohn Company Substituted azepino[4,5b]indoline derivatives
MXPA04001203A (en) * 2001-08-08 2004-05-20 Pharmacia & Upjhon Company THERAPEUTIC 1H-PYRIDO[4,3-b]INDOLES.
AU2007207508B2 (en) * 2006-01-19 2011-08-18 Athersys, Inc. Thiophenyl and pyrrolyl azepines as serotonin 5-HT2c receptor ligands and uses thereof
JP5501251B2 (en) 2008-01-11 2014-05-21 アルバニー モレキュラー リサーチ, インコーポレイテッド (1-Azinone) substituted pyridoindoles as MCH antagonists
US9073925B2 (en) 2009-07-01 2015-07-07 Albany Molecular Research, Inc. Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof
WO2011003007A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof
WO2011003012A1 (en) 2009-07-01 2011-01-06 Albany Molecular Research, Inc. Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof
EP2448585B1 (en) 2009-07-01 2014-01-01 Albany Molecular Research, Inc. Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof
US8697700B2 (en) 2010-12-21 2014-04-15 Albany Molecular Research, Inc. Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof
US8993765B2 (en) 2010-12-21 2015-03-31 Albany Molecular Research, Inc. Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE12641T1 (en) * 1979-11-02 1985-04-15 Sandoz Ag AZEPININDOLS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
FI831475L (en) 1983-11-07
PT76632B (en) 1986-01-27
IT8348232A0 (en) 1983-05-06
GB8312159D0 (en) 1983-06-08
DE3315467A1 (en) 1983-11-17
IT1197644B (en) 1988-12-06
BE896590A (en) 1983-10-28
NL8301552A (en) 1983-12-01
GB2120662B (en) 1985-09-11
DK199883D0 (en) 1983-05-04
FI831475A0 (en) 1983-04-29
IL68576A0 (en) 1983-09-30
JPS58203993A (en) 1983-11-28
ES8502440A1 (en) 1985-01-01
AU1425683A (en) 1983-11-10
SE8302554L (en) 1983-11-07
FR2526434A1 (en) 1983-11-10
GB2120662A (en) 1983-12-07
SE8302554D0 (en) 1983-05-04
PT76632A (en) 1983-06-01
HU189275B (en) 1986-06-30
ES522008A0 (en) 1985-01-01
CH649553A5 (en) 1985-05-31
DK199883A (en) 1983-11-07

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