ES530392A0 - Un metodo para preparar derivados de 4-hidroxi-2-quinolona. - Google Patents

Un metodo para preparar derivados de 4-hidroxi-2-quinolona.

Info

Publication number
ES530392A0
ES530392A0 ES530392A ES530392A ES530392A0 ES 530392 A0 ES530392 A0 ES 530392A0 ES 530392 A ES530392 A ES 530392A ES 530392 A ES530392 A ES 530392A ES 530392 A0 ES530392 A0 ES 530392A0
Authority
ES
Spain
Prior art keywords
hydroxy
preparing
quinolone derivatives
quinolone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES530392A
Other languages
English (en)
Other versions
ES8504719A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Shinyaku Co Ltd
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of ES530392A0 publication Critical patent/ES530392A0/es
Publication of ES8504719A1 publication Critical patent/ES8504719A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/10Expectorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
ES530392A 1982-06-21 1984-03-08 Un metodo para preparar derivados de 4-hidroxi-2-quinolona. Expired ES8504719A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57107366A JPS58225065A (ja) 1982-06-21 1982-06-21 2−キノロン誘導体

Publications (2)

Publication Number Publication Date
ES530392A0 true ES530392A0 (es) 1985-05-01
ES8504719A1 ES8504719A1 (es) 1985-05-01

Family

ID=14457260

Family Applications (4)

Application Number Title Priority Date Filing Date
ES523419A Expired ES8504130A1 (es) 1982-06-21 1983-06-20 Un metodo para preparar derivados de 4-hidroxi-2-quinolona
ES530391A Granted ES530391A0 (es) 1982-06-21 1984-03-08 Un metodo para preparar derivados de 4-hidroxi-2-quinolona.
ES530393A Granted ES530393A0 (es) 1982-06-21 1984-03-08 Un metodo para preparar derivados de 4-hidroxi-2-quinolonas.
ES530392A Expired ES8504719A1 (es) 1982-06-21 1984-03-08 Un metodo para preparar derivados de 4-hidroxi-2-quinolona.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES523419A Expired ES8504130A1 (es) 1982-06-21 1983-06-20 Un metodo para preparar derivados de 4-hidroxi-2-quinolona
ES530391A Granted ES530391A0 (es) 1982-06-21 1984-03-08 Un metodo para preparar derivados de 4-hidroxi-2-quinolona.
ES530393A Granted ES530393A0 (es) 1982-06-21 1984-03-08 Un metodo para preparar derivados de 4-hidroxi-2-quinolonas.

Country Status (7)

Country Link
US (1) US4526894A (es)
EP (1) EP0101330B1 (es)
JP (1) JPS58225065A (es)
KR (1) KR900004041B1 (es)
CA (1) CA1191140A (es)
DE (1) DE3377797D1 (es)
ES (4) ES8504130A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5916878A (ja) * 1982-07-20 1984-01-28 Mitsubishi Yuka Yakuhin Kk 2,4−ジヒドロキシ−3−アセチルキノリン類の製造方法
CA2091172C (en) * 1990-09-07 1997-05-20 Adriano Afonso Antiviral compounds and antihypertensive compounds
US5179107A (en) * 1990-09-07 1993-01-12 Schering Corporation Antiviral quinolinone compounds
AU8448491A (en) * 1990-09-07 1992-03-30 Schering Corporation Antiviral compounds and antihypertensive compounds
US5179093A (en) * 1991-05-10 1993-01-12 Schering Corporation Quinoline-diones
JP2943725B2 (ja) * 1996-01-17 1999-08-30 大日本インキ化学工業株式会社 キノリノン誘導体及びそれを有効成分とする抗アレルギー剤
KR100908418B1 (ko) 2001-06-20 2009-07-21 액티버스 파마 컴퍼니 리미티드 퀴놀리논 유도체 의약 조성물 및 그의 제조 방법
GB0519969D0 (en) * 2005-09-30 2005-11-09 Argenta Discovery Ltd Quinoline compounds
PT1928457E (pt) * 2005-09-30 2013-02-19 Pulmagen Therapeutics Asthma Ltd Quinolinas e sua utilização terapêutica
CA2680682C (en) * 2007-04-04 2015-05-26 Argenta Discovery Limited Quinolines and their therapeutic use
CN102171214B (zh) * 2008-08-06 2015-06-24 生物马林药物股份有限公司 聚(adp-核糖)聚合酶(parp)的二氢吡啶并酞嗪酮抑制剂
CA2787844C (en) 2010-02-03 2019-08-27 Biomarin Pharmaceutical Inc. Dihydropyridophthalazinone inhibitors of poly(adp-ribose) polymerase (parp) for use in treatment of diseases associated with a pten deficiency
HUE030794T2 (en) * 2010-02-08 2017-06-28 Medivation Technologies Inc Synthesis Processes of Dihydro-Pyrido-Phthalazinone Derivatives
AR083502A1 (es) 2010-10-21 2013-02-27 Biomarin Pharm Inc Sal tosilada de (8s,9r)-5-fluoro-8-(4-fluorofenil)-9-(1-metil-1h-1,2,4-triazol-5-il)-8,9-dihidro-2h-pirido[4,3,2-de]ftalazin-3(7h)-ona cristalina
CN102146068A (zh) * 2011-01-20 2011-08-10 南开大学 3-苯甲酰基-4-羟基香豆素衍生物及其类似物与在除草方面的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770480B2 (de) * 1968-05-22 1977-09-29 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2,4- dihydroxychinolin
CH606285A5 (es) * 1974-12-17 1978-10-31 Ciba Geigy Ag
US4086349A (en) * 1975-07-30 1978-04-25 Mitsubishi Yuka Pharmaceutical Co., Ltd. Quinolopyran-4-one-2-carboxylic acid derivatives and salts thereof as novel compounds and as medicines for treatment of allergic asthma
DE2806879A1 (de) * 1978-02-17 1979-08-23 Sandoz Ag 4-hydroxy-2-chinolinon-3-carbonsaeure- esterderivate
ATE27451T1 (de) * 1981-03-24 1987-06-15 Ciba Geigy Ag Acyl-chinolinonderivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische praeparate und ihre verwendung.

Also Published As

Publication number Publication date
ES8504718A1 (es) 1985-05-01
JPS58225065A (ja) 1983-12-27
JPH0249306B2 (es) 1990-10-29
EP0101330A3 (en) 1984-08-22
KR840005101A (ko) 1984-11-03
DE3377797D1 (en) 1988-09-29
ES8504723A1 (es) 1985-05-01
EP0101330A2 (en) 1984-02-22
ES530393A0 (es) 1985-05-01
CA1191140A (en) 1985-07-30
ES8504719A1 (es) 1985-05-01
EP0101330B1 (en) 1988-08-24
ES523419A0 (es) 1985-04-01
ES530391A0 (es) 1985-05-01
KR900004041B1 (ko) 1990-06-09
US4526894A (en) 1985-07-02
ES8504130A1 (es) 1985-04-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401