DE3243073A1 - 23-dehydro-25-hydroxyvitamin d(pfeil abwaerts)3(pfeil abwaerts) - Google Patents

23-dehydro-25-hydroxyvitamin d(pfeil abwaerts)3(pfeil abwaerts)

Info

Publication number
DE3243073A1
DE3243073A1 DE19823243073 DE3243073A DE3243073A1 DE 3243073 A1 DE3243073 A1 DE 3243073A1 DE 19823243073 DE19823243073 DE 19823243073 DE 3243073 A DE3243073 A DE 3243073A DE 3243073 A1 DE3243073 A1 DE 3243073A1
Authority
DE
Germany
Prior art keywords
hydroxyvitamin
dehydro
compound according
vitamin
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19823243073
Other languages
German (de)
English (en)
Inventor
Hector F. Deluca
Heinrich K. 53705 Madison Wis. Schnoes
Joseph K. 53704 Madison Wis. Wichmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of DE3243073A1 publication Critical patent/DE3243073A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14All rings being cycloaliphatic
    • C07C2602/24All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19823243073 1981-12-11 1982-11-22 23-dehydro-25-hydroxyvitamin d(pfeil abwaerts)3(pfeil abwaerts) Withdrawn DE3243073A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/329,845 US4360471A (en) 1981-12-11 1981-12-11 23-Dehydro-25-hydroxyvitamin D3

Publications (1)

Publication Number Publication Date
DE3243073A1 true DE3243073A1 (de) 1983-06-16

Family

ID=23287260

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19823243073 Withdrawn DE3243073A1 (de) 1981-12-11 1982-11-22 23-dehydro-25-hydroxyvitamin d(pfeil abwaerts)3(pfeil abwaerts)

Country Status (5)

Country Link
US (1) US4360471A (enExample)
JP (1) JPS58116458A (enExample)
DE (1) DE3243073A1 (enExample)
FR (1) FR2518091B1 (enExample)
GB (1) GB2111504B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0325279A1 (de) * 1988-01-20 1989-07-26 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate
EP0326875A1 (de) * 1988-01-20 1989-08-09 F. Hoffmann-La Roche Ag Didehydro-vitamin D3-Derivate

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4456689A (en) * 1982-05-17 1984-06-26 Becton Dickinson And Company Competitive protein binding assay using an organosilane-silica gel separation medium
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
DE3590080T (de) * 1984-03-05 1986-02-20 Wisconsin Alumni Research Foundation, Madison, Wis. 1α-Hydroxyvitamin D↓2↓-Analogverbindungen und Verfahren zu deren Herstellung
TW267161B (enExample) * 1992-11-20 1996-01-01 Hoffmann La Roche
CA2175881A1 (en) * 1995-05-09 1996-11-10 Andrzej Kutner Vitamin d compounds and methods of preparing these compounds
US20100196308A1 (en) 2009-01-27 2010-08-05 Jimenez Joaquin J Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
CN102655869B (zh) 2009-08-14 2016-08-10 博格有限责任公司 用于治疗脱发的维生素d3及其类似物
CN105492081A (zh) 2013-05-29 2016-04-13 博格有限责任公司 使用维生素d预防或减轻化疗诱发的脱发

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3786062A (en) * 1973-02-16 1974-01-15 Wisconsin Alumni Res Found 22-dehydro-25-hydroxycholecalciferol and process for preparing same
US4263214A (en) * 1978-07-26 1981-04-21 Wisconsin Alumni Research Foundation Fluorovitamin D compounds and processes for their preparation
US4292250A (en) * 1980-11-17 1981-09-29 Wisconsin Alumni Research Foundation Vitamin D derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0325279A1 (de) * 1988-01-20 1989-07-26 F. Hoffmann-La Roche Ag Dehydrocholecalciferolderivate
EP0326875A1 (de) * 1988-01-20 1989-08-09 F. Hoffmann-La Roche Ag Didehydro-vitamin D3-Derivate

Also Published As

Publication number Publication date
FR2518091B1 (fr) 1985-06-28
JPH0348178B2 (enExample) 1991-07-23
GB2111504A (en) 1983-07-06
GB2111504B (en) 1985-08-07
JPS58116458A (ja) 1983-07-11
FR2518091A1 (fr) 1983-06-17
US4360471A (en) 1982-11-23

Similar Documents

Publication Publication Date Title
Esvelt et al. Isolation and characterization of 1. alpha.-hydroxy-23-carboxytetranorvitamin D: a major metabolite of 1, 25-dihydroxyvitamin D3
Frolik et al. Metabolism of 1, 25-dihydroxycholecalciferol in the rat
DE2526981C3 (de) lalpha^4-Dihyaroxycholecalciferol-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Mittel
DE3045287C2 (enExample)
DE3933034A1 (de) 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
DE3243073A1 (de) 23-dehydro-25-hydroxyvitamin d(pfeil abwaerts)3(pfeil abwaerts)
EP0450743A1 (de) 24-Oxa-Derivate in der Vitamin D-Reihe
CH650240A5 (de) 24,24-difluor-1alpha,25-dihydroxycholecalciferol.
CH668258A5 (de) Hydroxyvitamin d2-isomere.
Tanaka et al. Synthesis of 24S and 24R-hydroxy-[24-3H] vitamin D3 and their metabolism in rachitic rats
CH654015A5 (de) 24,24-difluor-25-hydroxycholesterin-7-en und dessen 3-acylderivate.
DE3243150A1 (de) Trihydroxy-vitamin-d(pfeil abwaerts)3(pfeil abwaerts)-verbindungen
DE2838092A1 (de) 1 alpha -hydroxy-24-oxovitamin d tief 3 , verfahren zu seiner herstellung, dabei verwendete vorlaeufer und verwendung von 1 alpha -hydroxy-24-oxovitamin d tief 3
DE3590021C2 (de) 1alpha-Hydroxyvitamin D-Derivat und dieses enthaltendes Arzneimittel
DE69808316T2 (de) All-trans-retinol-metabolit
Partridge et al. (25 S)‐1α, 25, 26‐Trihydroxycholecalciferol, a New Vitamin D3 Metabolite: Synthesis and Absolute Stereochemistry at C (25)
DE3045288C2 (enExample)
DE3590080C2 (enExample)
US4223131A (en) 25-Hydroxycholecalciferol-26,23-lactone
Lawson et al. Biological activity of 10-hydroxy-vitamin D3 implications for the steric structure of the active form of vitamin D
DE2518843C3 (de) Verfahren zu seiner Herstellung
DE2433949C3 (de) 1,24,25-Trihydroxycholecalciferol sowie dieses enthaltendes Mittel
DE1933375B2 (de) 25-hydroxyverbindungen der vitamind-reihe, verfahren zu ihrer herstellung und 25-hydroxycholecalciferol enthaltendes mittel
DE1643159A1 (de) Verfahren zur Herstellung von Prostaglandinderivaten und Verbindungen mit prostaglandin-aehnlicher Aktivitaet
DE2953443C2 (de) 1ALPHA, 3beta-DIHYDROXY-9,10-seco-24-Norchola-5,7,10,(19)-trien-23-SAEURE UND ESTER DAVON.

Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee