DE3102217A1 - Plasminogenpraeparat und verfahren zu seiner herstellung - Google Patents

Plasminogenpraeparat und verfahren zu seiner herstellung

Info

Publication number
DE3102217A1
DE3102217A1 DE19813102217 DE3102217A DE3102217A1 DE 3102217 A1 DE3102217 A1 DE 3102217A1 DE 19813102217 DE19813102217 DE 19813102217 DE 3102217 A DE3102217 A DE 3102217A DE 3102217 A1 DE3102217 A1 DE 3102217A1
Authority
DE
Germany
Prior art keywords
salt
plasminogen
lysine
weight
physiologically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19813102217
Other languages
German (de)
English (en)
Other versions
DE3102217C2 (es
Inventor
Satoshi Katano Funakoshi
Mitsuomi Fukuchiyama Ohgaki
Yahiro Hirakata Uemura
Katsuhiro Sakurai Uriyu
Ryozo Takatsuki Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP807280A external-priority patent/JPS56106594A/ja
Priority claimed from JP9134180A external-priority patent/JPS5716824A/ja
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Publication of DE3102217A1 publication Critical patent/DE3102217A1/de
Application granted granted Critical
Publication of DE3102217C2 publication Critical patent/DE3102217C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
DE19813102217 1980-01-25 1981-01-23 Plasminogenpraeparat und verfahren zu seiner herstellung Granted DE3102217A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP807280A JPS56106594A (en) 1980-01-25 1980-01-25 Stabilizing method of plasminogen
JP9134180A JPS5716824A (en) 1980-07-03 1980-07-03 Plasminogen pharmaceutical and stabilizing method thereof

Publications (2)

Publication Number Publication Date
DE3102217A1 true DE3102217A1 (de) 1981-11-26
DE3102217C2 DE3102217C2 (es) 1987-02-12

Family

ID=26342511

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19813102217 Granted DE3102217A1 (de) 1980-01-25 1981-01-23 Plasminogenpraeparat und verfahren zu seiner herstellung

Country Status (5)

Country Link
CH (1) CH650273A5 (es)
DE (1) DE3102217A1 (es)
FR (1) FR2474313A1 (es)
GB (1) GB2068002B (es)
SE (2) SE459783B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3119157A1 (de) * 1981-05-14 1982-12-09 Behringwerke Ag, 3550 Marburg Verfahren zur herstellung von und danach hergestelltes plasminogen
CA2007545A1 (en) * 1989-01-13 1990-07-13 Yahiro Uemura Production method for protein-containing composition
AT402367B (de) * 1990-10-11 1997-04-25 Immuno Ag Pharmazeutische zubereitung auf basis von lys-plasminogen

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1492054B2 (de) * 1964-04-28 1973-01-04 Novo Terapeutisk Laboratorium A/S, Kopenhagen Verfahren zur Reinigung von menschlichem oder tierischem Plasminogen
DE2715748A1 (de) * 1976-04-07 1977-10-27 Choay Sa Zubereitungen auf der grundlage von verbindungen vom plasminogen-typ, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3066079A (en) * 1959-09-18 1962-11-27 American Cyanamid Co Methods for purifying plasminogen
US3865692A (en) * 1974-01-11 1975-02-11 Abbott Lab Method for making highly potent plasminogen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1492054B2 (de) * 1964-04-28 1973-01-04 Novo Terapeutisk Laboratorium A/S, Kopenhagen Verfahren zur Reinigung von menschlichem oder tierischem Plasminogen
DE2715748A1 (de) * 1976-04-07 1977-10-27 Choay Sa Zubereitungen auf der grundlage von verbindungen vom plasminogen-typ, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Rolle, M. - Mayr, A.: Mikrobiologie, Infektions- und Seuchenlehre für Tierärzte, Biologen und Agrarwissenschaftler, 1978, S. 137 *
Yale Journal of Biology and Medicine, 1954, S. 365-371 *

Also Published As

Publication number Publication date
SE8803798L (sv) 1988-10-24
DE3102217C2 (es) 1987-02-12
SE8100393L (sv) 1981-07-26
GB2068002A (en) 1981-08-05
GB2068002B (en) 1983-06-29
SE8803798D0 (sv) 1988-10-24
SE459783B (sv) 1989-08-07
FR2474313A1 (fr) 1981-07-31
FR2474313B1 (es) 1984-02-10
CH650273A5 (de) 1985-07-15

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
8125 Change of the main classification

Ipc: C12N 9/68

D2 Grant after examination
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Free format text: VOSSIUS, V., DIPL.-CHEM. DR.RER.NAT. TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT. RAUH, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN

8328 Change in the person/name/address of the agent

Free format text: TAUCHNER, P., DIPL.-CHEM. DR.RER.NAT. HEUNEMANN, D., DIPL.-PHYS. DR.RER.NAT. RAUH, P., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 8000 MUENCHEN

8339 Ceased/non-payment of the annual fee