DE3028873C2 - Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat) - Google Patents

Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat)

Info

Publication number
DE3028873C2
DE3028873C2 DE3028873A DE3028873A DE3028873C2 DE 3028873 C2 DE3028873 C2 DE 3028873C2 DE 3028873 A DE3028873 A DE 3028873A DE 3028873 A DE3028873 A DE 3028873A DE 3028873 C2 DE3028873 C2 DE 3028873C2
Authority
DE
Germany
Prior art keywords
isosorbide
dianhydro
nitrate
glucitol
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3028873A
Other languages
German (de)
English (en)
Other versions
DE3028873A1 (de
Inventor
Einhard Dr.rer.nat. 6800 Mannheim Kiegel
Karl Dr.Rer.Nat. 6905 Schriesheim Lauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6108470&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3028873(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE3028873A priority Critical patent/DE3028873C2/de
Priority to US06/276,773 priority patent/US4431829A/en
Priority to CA000381990A priority patent/CA1196631A/en
Priority to AT81105882T priority patent/ATE4458T1/de
Priority to DE8181105882T priority patent/DE3160767D1/de
Priority to EP81105882A priority patent/EP0045076B1/de
Priority to DD81232126A priority patent/DD201597A5/de
Priority to JP56117219A priority patent/JPS5753489A/ja
Priority to CS815771A priority patent/CS228147B2/cs
Priority to FI812374A priority patent/FI76344C/fi
Priority to HU812216A priority patent/HU189526B/hu
Priority to IL63464A priority patent/IL63464A/xx
Priority to ES504449A priority patent/ES504449A0/es
Publication of DE3028873A1 publication Critical patent/DE3028873A1/de
Publication of DE3028873C2 publication Critical patent/DE3028873C2/de
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE3028873A 1980-07-30 1980-07-30 Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat) Expired DE3028873C2 (de)

Priority Applications (13)

Application Number Priority Date Filing Date Title
DE3028873A DE3028873C2 (de) 1980-07-30 1980-07-30 Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat)
US06/276,773 US4431829A (en) 1980-07-30 1981-06-24 Process for the preparation of 1,4:3,6-dianhydro-D glucitol 5-nitrate
CA000381990A CA1196631A (en) 1980-07-30 1981-07-17 Process for the preparation of 1,4:3,6-dianhydro-d- glucitol 5-nitrate
AT81105882T ATE4458T1 (de) 1980-07-30 1981-07-25 Verfahren zur herstellung von 1,4:3,6-dianhydro-d-glucit-5-nitrat (isosorbid-5-nitrat).
DE8181105882T DE3160767D1 (en) 1980-07-30 1981-07-25 Process for the preparation of 1,4:3,6-dianhydro-d-glucite-5-nitrate (isosobide-5-nitrate)
EP81105882A EP0045076B1 (de) 1980-07-30 1981-07-25 Verfahren zur Herstellung von 1,4:3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat)
DD81232126A DD201597A5 (de) 1980-07-30 1981-07-27 Verfahren zur herstellung von 1,4:3,6-dianhydro-d-glucit-5-nitrat(isosorbid-5-nitrat)
JP56117219A JPS5753489A (en) 1980-07-30 1981-07-28 Manufacture of 1,4:3,6-dianhydro-d- glucitol-5-nitrate
CS815771A CS228147B2 (en) 1980-07-30 1981-07-29 Preparation of 1,4 to 3,6-dianhydro-d-glucit-5-nitrates
FI812374A FI76344C (fi) 1980-07-30 1981-07-29 Foerfarande foer framstaellning av 1,4:3, 6-dianhydro-d-glusitol-5-nitrat (isosorbid-5-nitrat).
HU812216A HU189526B (en) 1980-07-30 1981-07-29 Process for preparing 1,4:3,6-dianhydro-d-glucitol-5-nitrate /isosorbide-5-nitrate/
IL63464A IL63464A (en) 1980-07-30 1981-07-29 Process for the production of 1,4:3,6-dianhydro-d-glucitol-5-nitrate and pharmaceutical compositions containing the compound produced by said process
ES504449A ES504449A0 (es) 1980-07-30 1981-07-30 Procedimiento para la preparacion de 1,4:3,6-dianhidro-d- glucita-5-nitrato

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3028873A DE3028873C2 (de) 1980-07-30 1980-07-30 Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat)

Publications (2)

Publication Number Publication Date
DE3028873A1 DE3028873A1 (de) 1982-02-11
DE3028873C2 true DE3028873C2 (de) 1983-10-27

Family

ID=6108470

Family Applications (2)

Application Number Title Priority Date Filing Date
DE3028873A Expired DE3028873C2 (de) 1980-07-30 1980-07-30 Verfahren zur Herstellung von 1,4 zu 3,6-Dianhydro-D-glucit-5-nitrat (Isosorbid-5-nitrat)
DE8181105882T Expired DE3160767D1 (en) 1980-07-30 1981-07-25 Process for the preparation of 1,4:3,6-dianhydro-d-glucite-5-nitrate (isosobide-5-nitrate)

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8181105882T Expired DE3160767D1 (en) 1980-07-30 1981-07-25 Process for the preparation of 1,4:3,6-dianhydro-d-glucite-5-nitrate (isosobide-5-nitrate)

Country Status (12)

Country Link
US (1) US4431829A (OSRAM)
EP (1) EP0045076B1 (OSRAM)
JP (1) JPS5753489A (OSRAM)
AT (1) ATE4458T1 (OSRAM)
CA (1) CA1196631A (OSRAM)
CS (1) CS228147B2 (OSRAM)
DD (1) DD201597A5 (OSRAM)
DE (2) DE3028873C2 (OSRAM)
ES (1) ES504449A0 (OSRAM)
FI (1) FI76344C (OSRAM)
HU (1) HU189526B (OSRAM)
IL (1) IL63464A (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3102947A1 (de) * 1981-01-29 1982-09-02 Heinrich Mack Nachf., 7918 Illertissen Verfahren zur herstellung von isosorbid-5-nitrat
DE3117612A1 (de) * 1981-05-05 1982-11-25 Cassella Ag, 6000 Frankfurt Verfahren zur herstellung von isosorbid-5-nitrat
DE3124410A1 (de) * 1981-06-22 1983-01-05 Heinrich Mack Nachf., 7918 Illertissen Verfahren zur herstellung von isosorbid-2-nitrat
DE3128102A1 (de) * 1981-07-16 1983-02-03 Cassella Ag, 6000 Frankfurt Verfahren zur herstellung von isosorbid-2-acylaten
JPS5818385A (ja) * 1981-07-27 1983-02-02 Toa Eiyou Kagaku Kogyo Kk イソソルビド−５−ニトレ−トの製造法
DE3229412A1 (de) * 1982-08-06 1984-02-09 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von dianhydrohexitol-gemischen aus hexitolen, dianhydro-idit enthaltende dianhydro-hexitol-gemischen und ihre verwendung zur herstellung von polymeren
DE4410997A1 (de) * 1994-03-30 1995-10-26 Isis Pharma Gmbh Pharmazeutische Zubereitungen und Arzneistoffe zur Prävention und Behandlung endothelialer Dysfunktionen
DE19726812A1 (de) * 1997-06-25 1999-01-07 Isis Pharma Gmbh Neue Derivate des Pentaerythrits, deren Herstellung und Verwendung sowie Intermediate zur Synthese derselben
DE102008050597A1 (de) 2008-10-09 2010-04-15 Actavis Deutschland Gmbh & Co. Kg Pharmazeutische Zubereitungen zur Anwendung in einem Verfahren zur therapeutischen Behandlung von Hörsturz
KR102107272B1 (ko) * 2013-12-19 2020-05-06 아처 다니엘 미드랜드 캄파니 글리콜 아실화에 있어서 향상된 위치선택성

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886186A (en) * 1971-04-29 1975-05-27 American Home Prod Mononitrate esters of 1,4:3,6-dianhydro-d-glucitol
US4065488A (en) * 1977-02-24 1977-12-27 American Home Products Corporation Process for preparing 1,4:3,6-dianhydro-D-glucitol 2-nitrate
DE2903927C2 (de) * 1979-02-02 1981-03-12 Sanol Schwarz-Monheim Gmbh, 4019 Monheim Verfahren zur selektiven Herstellung von Isosorbid-5-nitrat

Also Published As

Publication number Publication date
ATE4458T1 (de) 1983-09-15
EP0045076A1 (de) 1982-02-03
EP0045076B1 (de) 1983-08-17
DE3160767D1 (en) 1983-09-22
JPS5753489A (en) 1982-03-30
CA1196631A (en) 1985-11-12
IL63464A0 (en) 1981-10-30
HU189526B (en) 1986-07-28
ES8205805A1 (es) 1982-08-16
JPH0250908B2 (OSRAM) 1990-11-05
CS228147B2 (en) 1984-05-14
DD201597A5 (de) 1983-07-27
FI812374L (fi) 1982-01-31
IL63464A (en) 1985-02-28
FI76344C (fi) 1988-10-10
FI76344B (fi) 1988-06-30
DE3028873A1 (de) 1982-02-11
US4431829A (en) 1984-02-14
ES504449A0 (es) 1982-08-16

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee