DE3028005C2 - - Google Patents
Info
- Publication number
- DE3028005C2 DE3028005C2 DE3028005A DE3028005A DE3028005C2 DE 3028005 C2 DE3028005 C2 DE 3028005C2 DE 3028005 A DE3028005 A DE 3028005A DE 3028005 A DE3028005 A DE 3028005A DE 3028005 C2 DE3028005 C2 DE 3028005C2
- Authority
- DE
- Germany
- Prior art keywords
- phase
- temperature
- cosmetic
- dispersion
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000006185 dispersion Substances 0.000 claims abstract description 16
- 239000008384 inner phase Substances 0.000 claims abstract description 12
- 239000008385 outer phase Substances 0.000 claims abstract description 11
- 239000002537 cosmetic Substances 0.000 claims abstract description 8
- 238000004519 manufacturing process Methods 0.000 claims abstract description 4
- 239000012071 phase Substances 0.000 claims description 38
- 238000000034 method Methods 0.000 claims description 23
- 239000008346 aqueous phase Substances 0.000 claims description 18
- 239000000839 emulsion Substances 0.000 claims description 17
- 239000012074 organic phase Substances 0.000 claims description 10
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 9
- 238000004945 emulsification Methods 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 7
- -1 fatty acid esters Chemical class 0.000 claims description 6
- 239000003995 emulsifying agent Substances 0.000 claims description 5
- 235000011187 glycerol Nutrition 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 3
- 150000001298 alcohols Chemical class 0.000 claims description 3
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 3
- 229930195729 fatty acid Natural products 0.000 claims description 3
- 239000000194 fatty acid Substances 0.000 claims description 3
- 239000003755 preservative agent Substances 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 239000000126 substance Substances 0.000 claims description 3
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 229930195733 hydrocarbon Natural products 0.000 claims description 2
- 150000002430 hydrocarbons Chemical class 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 238000007711 solidification Methods 0.000 claims description 2
- 230000008023 solidification Effects 0.000 claims description 2
- 238000007865 diluting Methods 0.000 claims 1
- 239000004744 fabric Substances 0.000 claims 1
- 150000002334 glycols Chemical class 0.000 claims 1
- 239000012141 concentrate Substances 0.000 description 8
- 239000007795 chemical reaction product Substances 0.000 description 6
- 238000003860 storage Methods 0.000 description 5
- 239000012895 dilution Substances 0.000 description 4
- 238000010790 dilution Methods 0.000 description 4
- 238000000265 homogenisation Methods 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- 239000005662 Paraffin oil Substances 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000008271 cosmetic emulsion Substances 0.000 description 2
- SASYSVUEVMOWPL-NXVVXOECSA-N decyl oleate Chemical compound CCCCCCCCCCOC(=O)CCCCCCC\C=C/CCCCCCCC SASYSVUEVMOWPL-NXVVXOECSA-N 0.000 description 2
- 230000001804 emulsifying effect Effects 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 238000010327 methods by industry Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 239000004904 UV filter Substances 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 238000010923 batch production Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000008406 cosmetic ingredient Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000013530 defoamer Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 239000002960 lipid emulsion Substances 0.000 description 1
- 238000000386 microscopy Methods 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000002688 persistence Effects 0.000 description 1
- 239000008251 pharmaceutical emulsion Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- CTYRPMDGLDAWRQ-UHFFFAOYSA-N phenyl hydrogen sulfate Chemical compound OS(=O)(=O)OC1=CC=CC=C1 CTYRPMDGLDAWRQ-UHFFFAOYSA-N 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 235000002639 sodium chloride Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000037072 sun protection Effects 0.000 description 1
- OULAJFUGPPVRBK-UHFFFAOYSA-N tetratriacontan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO OULAJFUGPPVRBK-UHFFFAOYSA-N 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/068—Microemulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/50—Mixing liquids with solids
- B01F23/51—Methods thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/80—After-treatment of the mixture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Colloid Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803028005 DE3028005A1 (de) | 1980-07-24 | 1980-07-24 | Verfahren zur herstellung von pharmazeitischen und kosemtischen dispersionen |
| DE8181105543T DE3175716D1 (en) | 1980-07-24 | 1981-07-15 | Process for the preparation of pharmaceutical and cosmetic dispersions |
| EP81105543A EP0045008B1 (de) | 1980-07-24 | 1981-07-15 | Verfahren zur Herstellung von pharmazeutischen und kosmetischen Dispersionen |
| AT81105543T ATE24282T1 (de) | 1980-07-24 | 1981-07-15 | Verfahren zur herstellung von pharmazeutischen und kosmetischen dispersionen. |
| JP56113074A JPS5756409A (en) | 1980-07-24 | 1981-07-21 | Manufacture of drug and cosmetic dispersion |
| ES504221A ES8206178A1 (es) | 1980-07-24 | 1981-07-23 | Procedimiento para la obtencion de dispersiones farmaceuti- cas y cosmeticas |
| US06/422,336 US4446127A (en) | 1980-07-24 | 1982-09-23 | Process for the preparation of pharmaceutical and cosmetic dispersions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19803028005 DE3028005A1 (de) | 1980-07-24 | 1980-07-24 | Verfahren zur herstellung von pharmazeitischen und kosemtischen dispersionen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE3028005A1 DE3028005A1 (de) | 1982-02-18 |
| DE3028005C2 true DE3028005C2 (d) | 1988-02-04 |
Family
ID=6107973
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19803028005 Granted DE3028005A1 (de) | 1980-07-24 | 1980-07-24 | Verfahren zur herstellung von pharmazeitischen und kosemtischen dispersionen |
| DE8181105543T Expired DE3175716D1 (en) | 1980-07-24 | 1981-07-15 | Process for the preparation of pharmaceutical and cosmetic dispersions |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8181105543T Expired DE3175716D1 (en) | 1980-07-24 | 1981-07-15 | Process for the preparation of pharmaceutical and cosmetic dispersions |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4446127A (d) |
| EP (1) | EP0045008B1 (d) |
| JP (1) | JPS5756409A (d) |
| AT (1) | ATE24282T1 (d) |
| DE (2) | DE3028005A1 (d) |
| ES (1) | ES8206178A1 (d) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10208265A1 (de) * | 2002-02-26 | 2003-09-11 | Beiersdorf Ag | Verfahren zur Herstellung von Emulsionen |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3230289A1 (de) * | 1982-08-14 | 1984-02-16 | Bayer Ag, 5090 Leverkusen | Herstellung von pharmazeutischen oder kosmetischen dispersionen |
| DE3421468A1 (de) * | 1984-06-08 | 1985-12-19 | Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim | Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung |
| JPS63165021A (ja) * | 1986-12-25 | 1988-07-08 | Kawasaki Steel Corp | 電縫鋼管の製造方法 |
| LU87457A1 (fr) * | 1989-02-24 | 1990-09-19 | Oreal | Utilisation,comme composition cosmetique pour cheveux,d'une microdispersion de cire,et procede de traitement des cheveux avec une telle composition |
| DE69011679T2 (de) * | 1989-04-21 | 1995-02-16 | Techno Bio Kk | Flüssigemulsion ohne emulgator und verfahren und vorrichtung zum verfertigen der emulsion. |
| DE4337030A1 (de) * | 1993-10-29 | 1995-05-04 | Henkel Kgaa | Verfahren zur Herstellung von Wachsdispersionen |
| US6783766B2 (en) * | 2002-03-06 | 2004-08-31 | Dow Global Technologies Inc. | Process for preparing a cosmetic formulation |
| US7351749B2 (en) | 2002-12-16 | 2008-04-01 | Unilever Home & Personal Care Usa, Division Of Conopco, Inc. | Process for manufacture of personal care products utilizing a concentrate water phase |
| FR2996759B1 (fr) * | 2012-10-15 | 2015-01-16 | Oreal | Composition cosmetique de revetement des fibres keratiniques |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA629433A (en) * | 1961-10-17 | The Upjohn Company | Dermatological compositions | |
| US1347734A (en) * | 1918-12-30 | 1920-07-27 | Cew Judson A De | Method of making emulsions |
| US1882834A (en) * | 1929-08-15 | 1932-10-18 | J W Mortell Company | Asphalt emulsion and manufacture thereof |
| US2254049A (en) * | 1939-03-18 | 1941-08-26 | Schutte August Henry | Method for forming emulsions |
| FR1498294A (fr) * | 1966-03-11 | 1967-10-20 | Exxon Standard Sa | Procédé de préparation d'émulsions ou de dispersions très stables |
| US3579461A (en) * | 1967-11-20 | 1971-05-18 | Johnson & Son Inc S C | Emulsification process |
| US3635834A (en) * | 1969-12-22 | 1972-01-18 | Squibb & Sons Inc | Process for preparing semisolid emulsions |
| US4002733A (en) * | 1974-07-26 | 1977-01-11 | Minnesota Mining And Manufacturing Company | Sunscreening compositions |
| FR2478485A1 (fr) * | 1980-03-24 | 1981-09-25 | Oreal | Compositions cosmetiques ou pharmaceutiques sous forme d'emulsions stables du type huile-dans-l'eau |
-
1980
- 1980-07-24 DE DE19803028005 patent/DE3028005A1/de active Granted
-
1981
- 1981-07-15 AT AT81105543T patent/ATE24282T1/de not_active IP Right Cessation
- 1981-07-15 DE DE8181105543T patent/DE3175716D1/de not_active Expired
- 1981-07-15 EP EP81105543A patent/EP0045008B1/de not_active Expired
- 1981-07-21 JP JP56113074A patent/JPS5756409A/ja active Pending
- 1981-07-23 ES ES504221A patent/ES8206178A1/es not_active Expired
-
1982
- 1982-09-23 US US06/422,336 patent/US4446127A/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10208265A1 (de) * | 2002-02-26 | 2003-09-11 | Beiersdorf Ag | Verfahren zur Herstellung von Emulsionen |
Also Published As
| Publication number | Publication date |
|---|---|
| US4446127A (en) | 1984-05-01 |
| DE3028005A1 (de) | 1982-02-18 |
| EP0045008A3 (en) | 1983-01-26 |
| ATE24282T1 (de) | 1987-01-15 |
| ES504221A0 (es) | 1982-08-16 |
| EP0045008B1 (de) | 1986-12-17 |
| JPS5756409A (en) | 1982-04-05 |
| DE3175716D1 (en) | 1987-01-29 |
| ES8206178A1 (es) | 1982-08-16 |
| EP0045008A2 (de) | 1982-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| D2 | Grant after examination | ||
| 8363 | Opposition against the patent | ||
| 8330 | Complete renunciation |