DE3019250C2 - Verfahren zur Herstellung einer kristallinen Form von Flunisolid - Google Patents

Verfahren zur Herstellung einer kristallinen Form von Flunisolid

Info

Publication number
DE3019250C2
DE3019250C2 DE3019250A DE3019250A DE3019250C2 DE 3019250 C2 DE3019250 C2 DE 3019250C2 DE 3019250 A DE3019250 A DE 3019250A DE 3019250 A DE3019250 A DE 3019250A DE 3019250 C2 DE3019250 C2 DE 3019250C2
Authority
DE
Germany
Prior art keywords
flunisolide
water
solution
alkanol
added
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3019250A
Other languages
German (de)
English (en)
Other versions
DE3019250A1 (de
Inventor
Richard E. Palo Alto Calif. Jones
Jacquelyn A. Consepcion Smithers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Palo Alto LLC
Original Assignee
Roche Palo Alto LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Palo Alto LLC filed Critical Roche Palo Alto LLC
Publication of DE3019250A1 publication Critical patent/DE3019250A1/de
Application granted granted Critical
Publication of DE3019250C2 publication Critical patent/DE3019250C2/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE3019250A 1979-05-21 1980-05-20 Verfahren zur Herstellung einer kristallinen Form von Flunisolid Expired DE3019250C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4083079A 1979-05-21 1979-05-21

Publications (2)

Publication Number Publication Date
DE3019250A1 DE3019250A1 (de) 1980-12-04
DE3019250C2 true DE3019250C2 (de) 1982-11-11

Family

ID=21913206

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3019250A Expired DE3019250C2 (de) 1979-05-21 1980-05-20 Verfahren zur Herstellung einer kristallinen Form von Flunisolid

Country Status (17)

Country Link
JP (1) JPS55154997A (https=)
AU (1) AU532084B2 (https=)
BE (1) BE883381A (https=)
CA (1) CA1153761A (https=)
CH (1) CH643567A5 (https=)
DE (1) DE3019250C2 (https=)
DK (1) DK162530C (https=)
FR (1) FR2457303A1 (https=)
GB (1) GB2052506B (https=)
HK (1) HK40784A (https=)
IL (1) IL60128A (https=)
IT (1) IT1133092B (https=)
MY (1) MY8500694A (https=)
NL (1) NL189201C (https=)
NZ (1) NZ193778A (https=)
SE (1) SE431549B (https=)
SG (1) SG37585G (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1121513B (it) * 1979-05-28 1986-04-02 Chiesi Farma Spa Processo per la conversione di umo steroide antiinfiammatorio in una forma suscettibile di essere somministarta come aerosol
GB8432063D0 (en) 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX3864E (es) * 1975-05-27 1981-08-26 Syntex Corp Un proceso para prepara el compuesto cristalino 6-fluiro-11b 21-dihiroxi-16 17-isopropilidendioxipregna-1 4-dien-3 20-diona

Also Published As

Publication number Publication date
NZ193778A (en) 1982-03-16
CH643567A5 (de) 1984-06-15
IL60128A0 (en) 1980-07-31
JPS6258360B2 (https=) 1987-12-05
IT8067791A0 (it) 1980-05-20
FR2457303B1 (https=) 1983-05-13
NL8002902A (nl) 1980-11-25
CA1153761A (en) 1983-09-13
NL189201C (nl) 1993-02-01
HK40784A (en) 1984-05-18
SE8003761L (sv) 1980-11-22
AU532084B2 (en) 1983-09-15
FR2457303A1 (fr) 1980-12-19
SE431549B (sv) 1984-02-13
MY8500694A (en) 1985-12-31
AU5856680A (en) 1980-11-27
NL189201B (nl) 1992-09-01
GB2052506A (en) 1981-01-28
IT1133092B (it) 1986-07-09
BE883381A (fr) 1980-11-20
DK162530C (da) 1992-03-30
DK162530B (da) 1991-11-11
JPS55154997A (en) 1980-12-02
DK219280A (da) 1980-11-22
SG37585G (en) 1986-01-17
IL60128A (en) 1984-01-31
DE3019250A1 (de) 1980-12-04
GB2052506B (en) 1983-01-19

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Legal Events

Date Code Title Description
OB Request for examination as to novelty
8110 Request for examination paragraph 44
D2 Grant after examination