DE2831092A1 - Dihydrotriazinylthiomethyloxacephalosporine und ihre salze sowie verfahren zu ihrer herstellung - Google Patents

Dihydrotriazinylthiomethyloxacephalosporine und ihre salze sowie verfahren zu ihrer herstellung

Info

Publication number
DE2831092A1
DE2831092A1 DE19782831092 DE2831092A DE2831092A1 DE 2831092 A1 DE2831092 A1 DE 2831092A1 DE 19782831092 DE19782831092 DE 19782831092 DE 2831092 A DE2831092 A DE 2831092A DE 2831092 A1 DE2831092 A1 DE 2831092A1
Authority
DE
Germany
Prior art keywords
general formula
compound
group
compounds
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19782831092
Other languages
German (de)
English (en)
Inventor
Yoshio Hamashima
Wataru Nagata
Teruji Tsuji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE2831092A1 publication Critical patent/DE2831092A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
DE19782831092 1977-07-14 1978-07-14 Dihydrotriazinylthiomethyloxacephalosporine und ihre salze sowie verfahren zu ihrer herstellung Ceased DE2831092A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8471577A JPS5419990A (en) 1977-07-14 1977-07-14 Dihydrotriazinylthioxacephalosporin

Publications (1)

Publication Number Publication Date
DE2831092A1 true DE2831092A1 (de) 1979-02-01

Family

ID=13838358

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782831092 Ceased DE2831092A1 (de) 1977-07-14 1978-07-14 Dihydrotriazinylthiomethyloxacephalosporine und ihre salze sowie verfahren zu ihrer herstellung

Country Status (7)

Country Link
US (1) US4232151A (OSRAM)
JP (1) JPS5419990A (OSRAM)
CH (1) CH636100A5 (OSRAM)
DE (1) DE2831092A1 (OSRAM)
FR (1) FR2397419A1 (OSRAM)
GB (1) GB2001071B (OSRAM)
NL (1) NL190632C (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5690088A (en) * 1979-11-02 1981-07-21 Meiji Seika Kaisha Ltd Novel cephalosporin analog compound
JPS56103185A (en) * 1980-01-22 1981-08-18 Shionogi & Co Ltd Malonamidoxa-dethia-cephem compound
US4304774A (en) * 1980-09-17 1981-12-08 Eli Lilly And Company Bis-tetrazolmethyl substituted β-lactam antibiotics
JPS59104389A (ja) * 1982-12-06 1984-06-16 Shionogi & Co Ltd オキサセファム誘導体
JPS59139385A (ja) * 1982-12-23 1984-08-10 Shionogi & Co Ltd フルオロメチルチオオキサセフアロスポリン
JPS59118789A (ja) * 1982-12-27 1984-07-09 Shionogi & Co Ltd オキサセフエム誘導体、その製法および用途
EP0114751B1 (en) * 1983-01-21 1987-12-09 Beecham Group Plc Beta-lactam antibacterial agents
EP0188781B1 (en) * 1984-12-28 1990-10-24 Merck & Co. Inc. 1-oxa-1-dethia-cephalosporin compounds and antibacterial agent comprising the same
CN103183686B (zh) * 2011-12-30 2016-06-29 浙江新和成股份有限公司 7β-氨基-7α-甲氧基-3-头孢烯化合物的制备方法
KR102115644B1 (ko) * 2017-09-13 2020-05-27 주식회사 동도물산 7α-알콕시옥사세펨 중간체의 제조방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355209A1 (de) * 1972-11-06 1974-05-16 Merck & Co Inc Neue antibiotica
DE2527291A1 (de) * 1974-06-21 1976-01-08 Hoffmann La Roche Acylderivate
DE2651771A1 (de) * 1975-11-12 1977-05-26 Shionogi & Co 7-amino-3-methyl-1-oxadethia-3- cephem-4-carbonsaeure-derivate, verfahren zu ihrer herstellung, arzneimittel und zwischenprodukte

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091211A (en) * 1974-05-05 1978-05-23 Hoffmann-La Roche Inc. Cephalosporins
CA1085392A (en) * 1976-03-25 1980-09-09 Masayuki Narisada Arylmalonamido-1-oxadethiacephalosporins

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2355209A1 (de) * 1972-11-06 1974-05-16 Merck & Co Inc Neue antibiotica
DE2527291A1 (de) * 1974-06-21 1976-01-08 Hoffmann La Roche Acylderivate
DE2651771A1 (de) * 1975-11-12 1977-05-26 Shionogi & Co 7-amino-3-methyl-1-oxadethia-3- cephem-4-carbonsaeure-derivate, verfahren zu ihrer herstellung, arzneimittel und zwischenprodukte

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
Antimikrobial Agents and Chemotherapy, Vol. 15, 1979, S. 273-281 *
Antimikrobiol. Agents and Chemotherapy, Vol. 15, 1979, S. 273-280 *
C.R. Acad. Sc. Serie D 1977, S. 1847-1849 *
Münch med. Wschr. 126, 1984, S. 885-887 *
Münch med. Wschr. 131, 1989, S. 821 *
SAMMES, P.G.: Topics in Antibiotic Chemistry Vol. 4, 1980, Ellis Horwood Limited, John Wiley & Sons *

Also Published As

Publication number Publication date
GB2001071B (en) 1982-05-06
NL190632B (nl) 1994-01-03
US4232151A (en) 1980-11-04
NL190632C (nl) 1994-06-01
FR2397419A1 (fr) 1979-02-09
JPS613350B2 (OSRAM) 1986-01-31
JPS5419990A (en) 1979-02-15
GB2001071A (en) 1979-01-24
FR2397419B1 (OSRAM) 1981-07-03
CH636100A5 (de) 1983-05-13
NL7807593A (nl) 1979-01-16

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: VOSSIUS, V., DIPL.-CHEM. DR.RER.NAT. TAUCHNER, P.,

8131 Rejection