DE2758314A1 - Disubstituierte piperazine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel - Google Patents
Disubstituierte piperazine, verfahren zu ihrer herstellung und sie enthaltende arzneimittelInfo
- Publication number
- DE2758314A1 DE2758314A1 DE19772758314 DE2758314A DE2758314A1 DE 2758314 A1 DE2758314 A1 DE 2758314A1 DE 19772758314 DE19772758314 DE 19772758314 DE 2758314 A DE2758314 A DE 2758314A DE 2758314 A1 DE2758314 A1 DE 2758314A1
- Authority
- DE
- Germany
- Prior art keywords
- group
- piperazine
- general formula
- thiadiazol
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB54398/76A GB1560084A (en) | 1976-12-31 | 1976-12-31 | Disubstituted piperazines processes for their preparation and pharmaceutical mompositions containing them |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2758314A1 true DE2758314A1 (de) | 1978-07-06 |
Family
ID=10470884
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19772758314 Ceased DE2758314A1 (de) | 1976-12-31 | 1977-12-27 | Disubstituierte piperazine, verfahren zu ihrer herstellung und sie enthaltende arzneimittel |
Country Status (24)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2907536A1 (de) * | 1978-03-03 | 1979-09-06 | Science Union & Cie | Disubstituierte piperazine, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4421753A (en) * | 1982-01-15 | 1983-12-20 | American Cyanamid Company | 1-(5-Amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines |
| FR2519986A1 (fr) * | 1982-01-21 | 1983-07-22 | Adir | Nouveaux derives de benzodioxine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
| US5776963A (en) * | 1989-05-19 | 1998-07-07 | Hoechst Marion Roussel, Inc. | 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility |
| US5637592A (en) * | 1994-07-12 | 1997-06-10 | Janssen Pharmaceutica N.V. | Acyl derivatives of azolones |
| FR2799464B1 (fr) * | 1999-10-12 | 2001-12-28 | Norchim | Procede de fabrication de piperonyl piperazine par animation reductive |
| US10562869B2 (en) | 2014-03-17 | 2020-02-18 | Remynd Nv | Oxadiazole compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1595923A1 (de) * | 1965-02-20 | 1969-11-27 | Merck Ag E | 1-Aralkyl-4-(thiazolyl-2)-piperazine und Verfahren zu ihrer Herstellung |
| GB1307256A (en) * | 1970-09-15 | 1973-02-14 | Science Union & Cie | Piperazine derivatives and a process for their preparation |
| GB1369379A (en) * | 1972-04-07 | 1974-10-09 | Science Union & Cie | Benzodioxole derivatives and processes for preparing them |
| GB1407552A (en) * | 1973-04-02 | 1975-09-24 | Science Union & Cie | Disubstituted piperazines processes for their preparation and pharmaceutical compositions containing them |
-
1976
- 1976-12-31 GB GB54398/76A patent/GB1560084A/en not_active Expired
-
1977
- 1977-12-21 IE IE2597/77A patent/IE46284B1/en unknown
- 1977-12-22 FR FR7738727A patent/FR2376148A1/fr active Granted
- 1977-12-22 CA CA293,755A patent/CA1100968A/fr not_active Expired
- 1977-12-22 YU YU03043/77A patent/YU304377A/xx unknown
- 1977-12-22 DK DK572977A patent/DK572977A/da not_active Application Discontinuation
- 1977-12-23 AT AT927577A patent/AT358591B/de not_active IP Right Cessation
- 1977-12-24 OA OA56358A patent/OA05840A/xx unknown
- 1977-12-27 US US05/864,204 patent/US4177272A/en not_active Expired - Lifetime
- 1977-12-27 JP JP15854677A patent/JPS5384984A/ja active Granted
- 1977-12-27 SU SU772558955A patent/SU703021A3/ru active
- 1977-12-27 DE DE19772758314 patent/DE2758314A1/de not_active Ceased
- 1977-12-28 ZA ZA00777680A patent/ZA777680B/xx unknown
- 1977-12-29 IL IL53714A patent/IL53714A/xx unknown
- 1977-12-29 AR AR270568A patent/AR216931A1/es active
- 1977-12-29 AU AU32045/77A patent/AU513087B2/en not_active Expired
- 1977-12-29 SE SE7714884A patent/SE7714884L/xx unknown
- 1977-12-29 GR GR55066A patent/GR62407B/el unknown
- 1977-12-29 PH PH20605A patent/PH14321A/en unknown
- 1977-12-30 PT PT67486A patent/PT67486B/pt unknown
- 1977-12-30 BE BE184051A patent/BE862568A/xx unknown
- 1977-12-30 DD DD7700203032A patent/DD133802A5/xx unknown
- 1977-12-31 NL NL7714628A patent/NL7714628A/xx not_active Application Discontinuation
-
1978
- 1978-01-05 NZ NZ186158A patent/NZ186158A/xx unknown
- 1978-12-21 SU SU782699397A patent/SU793397A3/ru active
-
1979
- 1979-02-27 AR AR275634A patent/AR217143A1/es active
- 1979-02-27 AR AR275635A patent/AR217144A1/es active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2907536A1 (de) * | 1978-03-03 | 1979-09-06 | Science Union & Cie | Disubstituierte piperazine, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen |
Also Published As
| Publication number | Publication date |
|---|---|
| YU304377A (en) | 1983-01-21 |
| AU3204577A (en) | 1979-07-05 |
| GR62407B (en) | 1979-04-11 |
| IL53714A0 (en) | 1978-03-10 |
| JPS5384984A (en) | 1978-07-26 |
| CA1100968A (fr) | 1981-05-12 |
| AT358591B (de) | 1980-09-25 |
| BE862568A (fr) | 1978-06-30 |
| AU513087B2 (en) | 1980-11-13 |
| ZA777680B (en) | 1978-10-25 |
| IE46284L (en) | 1978-06-30 |
| JPS6149314B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1986-10-29 |
| DK572977A (da) | 1978-07-01 |
| GB1560084A (en) | 1980-01-30 |
| IL53714A (en) | 1981-07-31 |
| SE7714884L (sv) | 1978-07-02 |
| AR217144A1 (es) | 1980-02-29 |
| SU793397A3 (ru) | 1980-12-30 |
| NZ186158A (en) | 1980-03-05 |
| ATA927577A (de) | 1980-02-15 |
| IE46284B1 (en) | 1983-04-20 |
| US4177272A (en) | 1979-12-04 |
| SU703021A3 (ru) | 1979-12-05 |
| PT67486B (fr) | 1979-05-30 |
| DD133802A5 (de) | 1979-01-24 |
| AR217143A1 (es) | 1980-02-29 |
| FR2376148B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1981-05-29 |
| AR216931A1 (es) | 1980-02-15 |
| PT67486A (fr) | 1978-01-01 |
| OA05840A (fr) | 1981-05-31 |
| FR2376148A1 (fr) | 1978-07-28 |
| NL7714628A (nl) | 1978-07-04 |
| PH14321A (en) | 1981-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OAP | Request for examination filed | ||
| OD | Request for examination | ||
| 8131 | Rejection |