DE2731481A1 - Aspidospermidine - Google Patents

Aspidospermidine

Info

Publication number
DE2731481A1
DE2731481A1 DE19772731481 DE2731481A DE2731481A1 DE 2731481 A1 DE2731481 A1 DE 2731481A1 DE 19772731481 DE19772731481 DE 19772731481 DE 2731481 A DE2731481 A DE 2731481A DE 2731481 A1 DE2731481 A1 DE 2731481A1
Authority
DE
Germany
Prior art keywords
formula
alkali metal
aspidospermidine
carbanion
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19772731481
Other languages
German (de)
English (en)
Inventor
Alain Heymes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parcor SARL
Original Assignee
Parcor SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parcor SARL filed Critical Parcor SARL
Publication of DE2731481A1 publication Critical patent/DE2731481A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE19772731481 1976-07-13 1977-07-12 Aspidospermidine Ceased DE2731481A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7621431A FR2358147A1 (fr) 1976-07-13 1976-07-13 Aspidospermidines

Publications (1)

Publication Number Publication Date
DE2731481A1 true DE2731481A1 (de) 1978-01-19

Family

ID=9175673

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772731481 Ceased DE2731481A1 (de) 1976-07-13 1977-07-12 Aspidospermidine

Country Status (17)

Country Link
US (1) US4152519A (enExample)
JP (1) JPS539798A (enExample)
AT (1) AT358189B (enExample)
AU (1) AU512242B2 (enExample)
BE (1) BE856722A (enExample)
BR (1) BR7704588A (enExample)
CA (1) CA1085848A (enExample)
CH (1) CH622794A5 (enExample)
DE (1) DE2731481A1 (enExample)
ES (1) ES460400A1 (enExample)
FR (1) FR2358147A1 (enExample)
GB (1) GB1546308A (enExample)
IT (1) IT1081020B (enExample)
LU (1) LU77727A1 (enExample)
NL (1) NL7707721A (enExample)
NZ (1) NZ184636A (enExample)
ZA (1) ZA774039B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2439200A2 (fr) * 1978-10-19 1980-05-16 Sandoz Sa Nouveaux derives de la 1,2-didehydro-aspidospermidine, leur preparation et leur application comme medicaments
HU206883B (en) * 1990-12-18 1993-01-28 Richter Gedeon Vegyeszet Process for producing new 15-nitro-2-beta-, 3-beta-dihydro- and 15-nitro-2-beta, 3-beta-, 6,7-tetrahydro-tabersonin derivatives and pharmaceutical compositions containing them

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE765795A (fr) * 1971-04-15 1971-08-30 Omnium Chimique Sa Procede de preparation d'inverses optiques de la vincamine naturelle etderives indoliques nouveaux.
FR2132733A1 (en) * 1971-04-07 1972-11-24 Omnium Chimique Sa (apo)vincine and 16-epivincine prepn
US3892755A (en) * 1971-01-15 1975-07-01 Omnium Chimique Sa Process of preparation of vincamine from tabersonine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2242395B1 (enExample) * 1973-06-22 1978-10-20 Omnium Chimique Sa

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3892755A (en) * 1971-01-15 1975-07-01 Omnium Chimique Sa Process of preparation of vincamine from tabersonine
FR2132733A1 (en) * 1971-04-07 1972-11-24 Omnium Chimique Sa (apo)vincine and 16-epivincine prepn
BE765795A (fr) * 1971-04-15 1971-08-30 Omnium Chimique Sa Procede de preparation d'inverses optiques de la vincamine naturelle etderives indoliques nouveaux.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
C.R.Acad.Sc. Paris, t.274, 1972, 1350-1352 *

Also Published As

Publication number Publication date
ZA774039B (en) 1978-05-30
AT358189B (de) 1980-08-25
FR2358147B1 (enExample) 1978-12-15
GB1546308A (en) 1979-05-23
IT1081020B (it) 1985-05-16
AU512242B2 (en) 1980-10-02
CA1085848A (fr) 1980-09-16
CH622794A5 (enExample) 1981-04-30
BE856722A (fr) 1978-01-12
BR7704588A (pt) 1978-04-04
US4152519A (en) 1979-05-01
NL7707721A (nl) 1978-01-17
ATA500077A (de) 1980-01-15
JPS539798A (en) 1978-01-28
AU2694777A (en) 1979-01-18
NZ184636A (en) 1980-04-28
LU77727A1 (enExample) 1977-10-07
ES460400A1 (es) 1978-05-01
FR2358147A1 (fr) 1978-02-10

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8128 New person/name/address of the agent

Representative=s name: BARTELS, H. HELD, M., DIPL.-ING. DR.-ING., PAT.-AN

8131 Rejection