FR2358147A1 - Aspidospermidines - Google Patents

Aspidospermidines

Info

Publication number
FR2358147A1
FR2358147A1 FR7621431A FR7621431A FR2358147A1 FR 2358147 A1 FR2358147 A1 FR 2358147A1 FR 7621431 A FR7621431 A FR 7621431A FR 7621431 A FR7621431 A FR 7621431A FR 2358147 A1 FR2358147 A1 FR 2358147A1
Authority
FR
France
Prior art keywords
aspidospermidins
homologues
aspidospermidines
vincadifformin
aspidospermidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7621431A
Other languages
English (en)
Other versions
FR2358147B1 (fr
Inventor
Alain Heymes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Parcor SARL
Original Assignee
Parcor SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parcor SARL filed Critical Parcor SARL
Priority to FR7621431A priority Critical patent/FR2358147A1/fr
Priority to CA281,276A priority patent/CA1085848A/fr
Priority to ES460400A priority patent/ES460400A1/es
Priority to ZA00774039A priority patent/ZA774039B/xx
Priority to US05/813,670 priority patent/US4152519A/en
Priority to LU77727A priority patent/LU77727A1/xx
Priority to IT12681/77A priority patent/IT1081020B/it
Priority to AU26947/77A priority patent/AU512242B2/en
Priority to BE179265A priority patent/BE856722A/fr
Priority to GB29234/77A priority patent/GB1546308A/en
Priority to NL7707721A priority patent/NL7707721A/xx
Priority to AT500077A priority patent/AT358189B/de
Priority to CH862677A priority patent/CH622794A5/fr
Priority to DE19772731481 priority patent/DE2731481A1/de
Priority to BR7704588A priority patent/BR7704588A/pt
Priority to NZ184636A priority patent/NZ184636A/xx
Priority to JP8399277A priority patent/JPS539798A/ja
Publication of FR2358147A1 publication Critical patent/FR2358147A1/fr
Application granted granted Critical
Publication of FR2358147B1 publication Critical patent/FR2358147B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

a. Aspidospermidines. b. La déhydro-1,2 carbométhoxy-16 hydroxy-16 aspidospermidine et ses homologues peuvent être préparés à partir de la vincadifformine et homologues. c. Vasodilatateurs.
FR7621431A 1976-07-13 1976-07-13 Aspidospermidines Granted FR2358147A1 (fr)

Priority Applications (17)

Application Number Priority Date Filing Date Title
FR7621431A FR2358147A1 (fr) 1976-07-13 1976-07-13 Aspidospermidines
CA281,276A CA1085848A (fr) 1976-07-13 1977-06-23 Aspidospermidines
ES460400A ES460400A1 (es) 1976-07-13 1977-07-05 Procedimiento de preparacion de las aspidospermidinas.
ZA00774039A ZA774039B (en) 1976-07-13 1977-07-05 Aspidospermidines
US05/813,670 US4152519A (en) 1976-07-13 1977-07-07 16-Hydroxy aspidospermidines and a process for their production
LU77727A LU77727A1 (fr) 1976-07-13 1977-07-11
DE19772731481 DE2731481A1 (de) 1976-07-13 1977-07-12 Aspidospermidine
BE179265A BE856722A (fr) 1976-07-13 1977-07-12 Aspidospermidines
IT12681/77A IT1081020B (it) 1976-07-13 1977-07-12 Metodo di fabbricazione di aspidospermidine
NL7707721A NL7707721A (nl) 1976-07-13 1977-07-12 Werkwijze ter bereiding van een geneesmiddel, zo gevormd geneesmiddel en werkwijze ter berei- ding van geschikte geneeskrachtige verbindingen.
AT500077A AT358189B (de) 1976-07-13 1977-07-12 Verfahren zur herstellung von neuen aspidosper- midinen
CH862677A CH622794A5 (fr) 1976-07-13 1977-07-12
AU26947/77A AU512242B2 (en) 1976-07-13 1977-07-12 Aspidospermidines
GB29234/77A GB1546308A (en) 1976-07-13 1977-07-12 16-hydroxy-16-carbonethoxy-aspidospermidines
BR7704588A BR7704588A (pt) 1976-07-13 1977-07-13 Processo de preparacao de intermediarios de sintese
NZ184636A NZ184636A (en) 1976-07-13 1977-07-13 16-methoxycarbonyl-16-hydroxyaspidospermidines
JP8399277A JPS539798A (en) 1976-07-13 1977-07-13 Production of aspidoospermidine and pharmaceutical preparation containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7621431A FR2358147A1 (fr) 1976-07-13 1976-07-13 Aspidospermidines

Publications (2)

Publication Number Publication Date
FR2358147A1 true FR2358147A1 (fr) 1978-02-10
FR2358147B1 FR2358147B1 (fr) 1978-12-15

Family

ID=9175673

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7621431A Granted FR2358147A1 (fr) 1976-07-13 1976-07-13 Aspidospermidines

Country Status (17)

Country Link
US (1) US4152519A (fr)
JP (1) JPS539798A (fr)
AT (1) AT358189B (fr)
AU (1) AU512242B2 (fr)
BE (1) BE856722A (fr)
BR (1) BR7704588A (fr)
CA (1) CA1085848A (fr)
CH (1) CH622794A5 (fr)
DE (1) DE2731481A1 (fr)
ES (1) ES460400A1 (fr)
FR (1) FR2358147A1 (fr)
GB (1) GB1546308A (fr)
IT (1) IT1081020B (fr)
LU (1) LU77727A1 (fr)
NL (1) NL7707721A (fr)
NZ (1) NZ184636A (fr)
ZA (1) ZA774039B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2439200A2 (fr) * 1978-10-19 1980-05-16 Sandoz Sa Nouveaux derives de la 1,2-didehydro-aspidospermidine, leur preparation et leur application comme medicaments

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU206883B (en) * 1990-12-18 1993-01-28 Richter Gedeon Vegyeszet Process for producing new 15-nitro-2-beta-, 3-beta-dihydro- and 15-nitro-2-beta, 3-beta-, 6,7-tetrahydro-tabersonin derivatives and pharmaceutical compositions containing them

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE763730R (fr) * 1971-01-15 1971-08-02 Omnium Chimique Sa Procede de preparation de la vincamine naturelle a partir de latabersonine et derives indoliques
BE765427A (fr) * 1971-04-07 1971-08-30 Omnium Chimique Sa Procede de preparation de la vincine naturelle a partir de la (-) mehtoxy-11-tabersonine et derives indoliques nouveaux.
BE765795A (fr) * 1971-04-15 1971-08-30 Omnium Chimique Sa Procede de preparation d'inverses optiques de la vincamine naturelle etderives indoliques nouveaux.
FR2242395B1 (fr) * 1973-06-22 1978-10-20 Omnium Chimique Sa

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2439200A2 (fr) * 1978-10-19 1980-05-16 Sandoz Sa Nouveaux derives de la 1,2-didehydro-aspidospermidine, leur preparation et leur application comme medicaments

Also Published As

Publication number Publication date
NL7707721A (nl) 1978-01-17
LU77727A1 (fr) 1977-10-07
AU2694777A (en) 1979-01-18
ATA500077A (de) 1980-01-15
ZA774039B (en) 1978-05-30
US4152519A (en) 1979-05-01
GB1546308A (en) 1979-05-23
BR7704588A (pt) 1978-04-04
AU512242B2 (en) 1980-10-02
NZ184636A (en) 1980-04-28
AT358189B (de) 1980-08-25
FR2358147B1 (fr) 1978-12-15
BE856722A (fr) 1978-01-12
IT1081020B (it) 1985-05-16
ES460400A1 (es) 1978-05-01
CH622794A5 (fr) 1981-04-30
CA1085848A (fr) 1980-09-16
JPS539798A (en) 1978-01-28
DE2731481A1 (de) 1978-01-19

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Legal Events

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