DE2704895A1 - Verbindungen mit stimulierender wirkung auf beta-adrenorezeptoren, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents

Verbindungen mit stimulierender wirkung auf beta-adrenorezeptoren, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Info

Publication number
DE2704895A1
DE2704895A1 DE19772704895 DE2704895A DE2704895A1 DE 2704895 A1 DE2704895 A1 DE 2704895A1 DE 19772704895 DE19772704895 DE 19772704895 DE 2704895 A DE2704895 A DE 2704895A DE 2704895 A1 DE2704895 A1 DE 2704895A1
Authority
DE
Germany
Prior art keywords
methyl
hydroxy
benzenedimethanol
formula
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19772704895
Other languages
German (de)
English (en)
Inventor
Ian Collins
Philip David Wicks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allen and Hanburys Ltd
Original Assignee
Allen and Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB4929/76A external-priority patent/GB1551260A/en
Application filed by Allen and Hanburys Ltd filed Critical Allen and Hanburys Ltd
Publication of DE2704895A1 publication Critical patent/DE2704895A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19772704895 1976-02-09 1977-02-05 Verbindungen mit stimulierender wirkung auf beta-adrenorezeptoren, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel Ceased DE2704895A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB4929/76A GB1551260A (en) 1976-02-09 1976-02-09 Phenylethanolamine derivatives
GB3518276 1976-08-24

Publications (1)

Publication Number Publication Date
DE2704895A1 true DE2704895A1 (de) 1977-08-11

Family

ID=26239472

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772704895 Ceased DE2704895A1 (de) 1976-02-09 1977-02-05 Verbindungen mit stimulierender wirkung auf beta-adrenorezeptoren, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Country Status (10)

Country Link
US (1) US4154761A (enExample)
JP (1) JPS5297926A (enExample)
AU (1) AU509065B2 (enExample)
CH (1) CH630603A5 (enExample)
DE (1) DE2704895A1 (enExample)
DK (1) DK148444C (enExample)
ES (2) ES455741A1 (enExample)
FR (1) FR2362114A1 (enExample)
NL (1) NL7701304A (enExample)
SE (1) SE440348B (enExample)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002867A1 (en) * 1977-12-27 1979-07-11 Technobiotic Ltd. 5-(2-Anilinoalkylamino-1-hydroxyalkyl)salicylamides, their preparation and anti-hypertensive compositions containing them
EP0006298A1 (en) * 1978-06-15 1980-01-09 Imperial Chemical Industries Plc Anti-inflammatory 1-phenyl-2-aminoethanol derivatives, pharmaceutical compositions thereof for topical use, and processes for their manufacture
EP0171689A1 (de) * 1984-08-02 1986-02-19 Roche Diagnostics GmbH Neue Aminoalkohole, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel und Zwischenprodukte
WO1997021665A1 (en) * 1995-12-08 1997-06-19 Glaxo Group Limited Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors
WO1997021666A1 (en) * 1995-12-08 1997-06-19 Glaxo Group Limited Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4304790A (en) * 1979-06-12 1981-12-08 Schering Corporation 2-(Alkylthio, alkylsulfinyl or alkylsulfonyl)-4-[2-anilinoalkylamino)-1-hydroxyethyl]phenols and derivatives thereof
ZW6584A1 (en) * 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
AU582573B2 (en) * 1984-04-17 1989-04-06 Glaxo Group Limited Phenethanolamine compounds
US5011993A (en) * 1986-09-05 1991-04-30 Schering Corporation Method for the preparation of α1 [[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-1,3-benzenedimethanol
US4952729A (en) * 1986-09-05 1990-08-28 Schering-Plough Corp. Intermediates in the preparation of alpha1(((1,1-dimethylethyl) amino) methyl)-4-hydroxy-1,3-benzenedimethanol
AU2737295A (en) * 1994-06-09 1996-01-04 Glaxo Group Limited Phenethanolamine derivatives and their use as atypical beta-adrenoceptor agonists

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1643224A1 (de) * 1966-09-23 1972-03-02 Allen & Hanburys Ltd 1-Phenyl-2-aminoaethanolderivate und Verfahren zu ihrer Herstellung und ihre Verwendung
US3879442A (en) * 1972-07-27 1975-04-22 Warner Lambert Co 5-hydroxy-{60 (substituted aminomethyl)-mu-xylene-{60 ,{60 -diols

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT334335B (de) * 1973-03-01 1976-01-10 Basf Ag Verfahren zur herstellung von 1-phenyl-2-aminoathanolen-(1)
AT219581B (de) * 1959-06-26 1962-02-12 Donau Pharmazie Gmbh Verfahren zur Herstellung von neuen Anilinen
DE1618005A1 (de) * 1966-09-22 1971-09-09 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen
GB1301134A (en) * 1970-07-18 1972-12-29 Pfizer Ltd SUBSTITUTED 1-PHENYL-2-ALLYLAMINO-ALKANOLS, 1-PHENYL-2-ALLYLAMINO-ALKANES AND alpha-AMINOALKYLPHENYL KETONES
AT310146B (de) * 1971-04-26 1973-09-25 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen N,N'-Bis-(β-hydroxyaryläthyl)-diaminoalkanen und deren Säureadditionssalzen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1643224A1 (de) * 1966-09-23 1972-03-02 Allen & Hanburys Ltd 1-Phenyl-2-aminoaethanolderivate und Verfahren zu ihrer Herstellung und ihre Verwendung
US3879442A (en) * 1972-07-27 1975-04-22 Warner Lambert Co 5-hydroxy-{60 (substituted aminomethyl)-mu-xylene-{60 ,{60 -diols

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002867A1 (en) * 1977-12-27 1979-07-11 Technobiotic Ltd. 5-(2-Anilinoalkylamino-1-hydroxyalkyl)salicylamides, their preparation and anti-hypertensive compositions containing them
EP0006298A1 (en) * 1978-06-15 1980-01-09 Imperial Chemical Industries Plc Anti-inflammatory 1-phenyl-2-aminoethanol derivatives, pharmaceutical compositions thereof for topical use, and processes for their manufacture
EP0171689A1 (de) * 1984-08-02 1986-02-19 Roche Diagnostics GmbH Neue Aminoalkohole, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel und Zwischenprodukte
WO1997021665A1 (en) * 1995-12-08 1997-06-19 Glaxo Group Limited Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors
WO1997021666A1 (en) * 1995-12-08 1997-06-19 Glaxo Group Limited Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors
US6048872A (en) * 1995-12-08 2000-04-11 Glaxo Wellcome Inc. Arylethanolamine derivatives and their use as agonists of atypical beta-adrenoceptors

Also Published As

Publication number Publication date
FR2362114A1 (fr) 1978-03-17
AU509065B2 (en) 1980-04-17
AU2213377A (en) 1978-08-17
ES455741A1 (es) 1978-04-16
DK52977A (da) 1977-08-10
US4154761A (en) 1979-05-15
SE440348B (sv) 1985-07-29
ES467069A1 (es) 1979-10-16
CH630603A5 (de) 1982-06-30
SE7701379L (sv) 1977-08-10
FR2362114B1 (enExample) 1979-03-09
DK148444B (da) 1985-07-08
DK148444C (da) 1985-12-09
NL7701304A (nl) 1977-08-11
JPS5297926A (en) 1977-08-17

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection