DE2653621A1 - Cephalosporin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents

Cephalosporin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Info

Publication number
DE2653621A1
DE2653621A1 DE19762653621 DE2653621A DE2653621A1 DE 2653621 A1 DE2653621 A1 DE 2653621A1 DE 19762653621 DE19762653621 DE 19762653621 DE 2653621 A DE2653621 A DE 2653621A DE 2653621 A1 DE2653621 A1 DE 2653621A1
Authority
DE
Germany
Prior art keywords
methyl
carboxylic acid
ceph
thio
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19762653621
Other languages
German (de)
English (en)
Inventor
George Burton
Kenneth David Hardy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB48719/75A external-priority patent/GB1570582A/en
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of DE2653621A1 publication Critical patent/DE2653621A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DE19762653621 1975-11-27 1976-11-25 Cephalosporin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel Pending DE2653621A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB48719/75A GB1570582A (en) 1975-11-27 1975-11-27 Cephalosporins
GB1495276 1976-04-13

Publications (1)

Publication Number Publication Date
DE2653621A1 true DE2653621A1 (de) 1977-06-08

Family

ID=26250914

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19762653621 Pending DE2653621A1 (de) 1975-11-27 1976-11-25 Cephalosporin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Country Status (14)

Country Link
JP (1) JPS5278894A (fr)
AU (1) AU2008776A (fr)
DE (1) DE2653621A1 (fr)
DK (1) DK536176A (fr)
ES (2) ES453722A1 (fr)
FI (1) FI763363A (fr)
FR (1) FR2332757A1 (fr)
GR (1) GR61821B (fr)
IL (1) IL50945A0 (fr)
NL (1) NL7613243A (fr)
NO (1) NO764034L (fr)
NZ (1) NZ182649A (fr)
PH (1) PH13321A (fr)
SE (1) SE7613150L (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298605A (en) 1978-06-22 1981-11-03 Chugai Seiyaku Kabushiki Kaisha Cephalosporin derivatives

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4278670A (en) * 1976-07-12 1981-07-14 Smithkline Corporation 7-Alpha-oxyiminoacylcephalosporins
AU510280B2 (en) * 1976-08-30 1980-06-19 Bristol-Myers Company Antibacterial cephalosporin agents
JPS53155051U (fr) * 1977-05-10 1978-12-06
JPS54106495A (en) * 1978-02-09 1979-08-21 Dai Ichi Seiyaku Co Ltd Cephem derivative

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298605A (en) 1978-06-22 1981-11-03 Chugai Seiyaku Kabushiki Kaisha Cephalosporin derivatives
US4301161A (en) 1978-06-22 1981-11-17 Chugai Seiyaku Kabushiki Kaisha Cephalosporin derivatives
US4328224A (en) 1978-06-22 1982-05-04 Chugai Seiyaku Kabushiki Kaisha Cephalosporin derivatives
US4341776A (en) 1978-06-22 1982-07-27 Chugai Seiyaku Kabushiki Kaisha Cephalosporin derivatives

Also Published As

Publication number Publication date
DK536176A (da) 1977-05-28
ES475659A1 (es) 1979-10-16
SE7613150L (sv) 1977-05-28
ES453722A1 (es) 1979-06-01
PH13321A (en) 1980-03-13
NZ182649A (en) 1979-11-01
FI763363A (fr) 1977-05-28
NO764034L (fr) 1977-05-31
IL50945A0 (en) 1977-01-31
JPS5278894A (en) 1977-07-02
FR2332757A1 (fr) 1977-06-24
AU2008776A (en) 1978-06-08
GR61821B (en) 1979-01-22
NL7613243A (nl) 1977-06-01

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