DE2626802A1 - Vorrichtung und verfahren zum automatischen einfuellen einer bestimmten menge einer radioaktiven probenloesung in einen aufnahmebehaelter - Google Patents
Vorrichtung und verfahren zum automatischen einfuellen einer bestimmten menge einer radioaktiven probenloesung in einen aufnahmebehaelterInfo
- Publication number
- DE2626802A1 DE2626802A1 DE19762626802 DE2626802A DE2626802A1 DE 2626802 A1 DE2626802 A1 DE 2626802A1 DE 19762626802 DE19762626802 DE 19762626802 DE 2626802 A DE2626802 A DE 2626802A DE 2626802 A1 DE2626802 A1 DE 2626802A1
- Authority
- DE
- Germany
- Prior art keywords
- solution
- activity
- radioactive
- container
- receptacle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002285 radioactive effect Effects 0.000 title claims description 74
- 238000000034 method Methods 0.000 title claims description 20
- 239000012488 sample solution Substances 0.000 title claims description 19
- 239000000523 sample Substances 0.000 claims description 89
- 239000000243 solution Substances 0.000 claims description 65
- 230000000694 effects Effects 0.000 claims description 50
- 239000007788 liquid Substances 0.000 claims description 43
- 230000005855 radiation Effects 0.000 claims description 31
- 238000011049 filling Methods 0.000 claims description 28
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 27
- 230000001960 triggered effect Effects 0.000 claims description 18
- 238000012360 testing method Methods 0.000 claims description 17
- 238000010790 dilution Methods 0.000 claims description 13
- 239000012895 dilution Substances 0.000 claims description 13
- 229910052750 molybdenum Inorganic materials 0.000 claims description 13
- 239000011733 molybdenum Substances 0.000 claims description 13
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims description 12
- 239000003153 chemical reaction reagent Substances 0.000 claims description 9
- 239000012530 fluid Substances 0.000 claims description 8
- 239000011521 glass Substances 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 8
- 229920001296 polysiloxane Polymers 0.000 claims description 8
- 238000005259 measurement Methods 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 claims description 5
- 229940056501 technetium 99m Drugs 0.000 claims description 5
- 230000001681 protective effect Effects 0.000 claims description 4
- 239000007864 aqueous solution Substances 0.000 claims description 2
- 229910052751 metal Inorganic materials 0.000 claims description 2
- 239000002184 metal Substances 0.000 claims description 2
- 239000006193 liquid solution Substances 0.000 claims 5
- 238000004891 communication Methods 0.000 claims 3
- 239000003085 diluting agent Substances 0.000 claims 3
- 150000002751 molybdenum Chemical class 0.000 claims 1
- 230000009972 noncorrosive effect Effects 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000012528 membrane Substances 0.000 description 45
- 229910052713 technetium Inorganic materials 0.000 description 45
- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 description 45
- 230000000875 corresponding effect Effects 0.000 description 18
- 230000033001 locomotion Effects 0.000 description 18
- 239000007921 spray Substances 0.000 description 18
- 238000002347 injection Methods 0.000 description 17
- 239000007924 injection Substances 0.000 description 17
- 230000001105 regulatory effect Effects 0.000 description 15
- 239000000872 buffer Substances 0.000 description 13
- 238000004364 calculation method Methods 0.000 description 10
- 230000033228 biological regulation Effects 0.000 description 8
- 238000009826 distribution Methods 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 206010073306 Exposure to radiation Diseases 0.000 description 5
- 238000006073 displacement reaction Methods 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 239000005355 lead glass Substances 0.000 description 4
- 239000012876 carrier material Substances 0.000 description 3
- 238000013461 design Methods 0.000 description 3
- 238000005429 filling process Methods 0.000 description 3
- 238000003825 pressing Methods 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000007865 diluting Methods 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 239000000945 filler Substances 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 101100400378 Mus musculus Marveld2 gene Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 108010076504 Protein Sorting Signals Proteins 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000000157 blood function Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000007797 corrosion Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000011796 hollow space material Substances 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-M iodide Chemical compound [I-] XMBWDFGMSWQBCA-UHFFFAOYSA-M 0.000 description 1
- 229940006461 iodide ion Drugs 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000011572 manganese Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229950009740 molybdenum mo-99 Drugs 0.000 description 1
- 238000011017 operating method Methods 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 239000012857 radioactive material Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 229910052702 rhenium Inorganic materials 0.000 description 1
- WUAPFZMCVAUBPE-UHFFFAOYSA-N rhenium atom Chemical compound [Re] WUAPFZMCVAUBPE-UHFFFAOYSA-N 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J4/00—Feed or outlet devices; Feed or outlet control devices
- B01J4/02—Feed or outlet devices; Feed or outlet control devices for feeding measured, i.e. prescribed quantities of reagents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T1/00—Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
- G01T1/16—Measuring radiation intensity
- G01T1/17—Circuit arrangements not adapted to a particular type of detector
- G01T1/178—Circuit arrangements not adapted to a particular type of detector for measuring specific activity in the presence of other radioactive substances, e.g. natural, in the air or in liquids such as rain water
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01T—MEASUREMENT OF NUCLEAR OR X-RADIATION
- G01T7/00—Details of radiation-measuring instruments
- G01T7/02—Collecting means for receiving or storing samples to be investigated and possibly directly transporting the samples to the measuring arrangement; particularly for investigating radioactive fluids
Landscapes
- Chemical & Material Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Physics & Mathematics (AREA)
- High Energy & Nuclear Physics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measurement Of Radiation (AREA)
- Sampling And Sample Adjustment (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US587283A US3997784A (en) | 1975-06-16 | 1975-06-16 | Automatic apparatus for dispensing radiodiagnostic agents and method therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2626802A1 true DE2626802A1 (de) | 1976-12-23 |
Family
ID=24349169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19762626802 Pending DE2626802A1 (de) | 1975-06-16 | 1976-06-15 | Vorrichtung und verfahren zum automatischen einfuellen einer bestimmten menge einer radioaktiven probenloesung in einen aufnahmebehaelter |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3997784A (OSRAM) |
| JP (1) | JPS5286A (OSRAM) |
| AU (1) | AU1453376A (OSRAM) |
| BE (1) | BE842985A (OSRAM) |
| BR (1) | BR7603835A (OSRAM) |
| CA (1) | CA1046652A (OSRAM) |
| DD (1) | DD132546A5 (OSRAM) |
| DE (1) | DE2626802A1 (OSRAM) |
| DK (1) | DK268076A (OSRAM) |
| FR (1) | FR2315100A1 (OSRAM) |
| IL (1) | IL49793A0 (OSRAM) |
| IT (1) | IT1081210B (OSRAM) |
| NL (1) | NL7606467A (OSRAM) |
| NO (1) | NO762070L (OSRAM) |
| SE (1) | SE7606789L (OSRAM) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4144461A (en) * | 1977-01-17 | 1979-03-13 | Victoreen, Inc. | Method and apparatus for assay and storage of radioactive solutions |
| US4160910A (en) * | 1977-06-20 | 1979-07-10 | Union Carbide Corporation | Rechargeable 99MO/99MTC generator system |
| JPS5581807A (en) * | 1978-12-15 | 1980-06-20 | Nippon Tokushu Noyaku Seizo Kk | Repellent of bird |
| JPS5839949A (ja) * | 1981-09-02 | 1983-03-08 | Fujitetsuku:Kk | 放射性薬液調剤装置 |
| JPS5913792A (ja) * | 1982-07-15 | 1984-01-24 | Kanesho Kk | 有機リン酸エステル化合物及びその製造法並にこれを有効成分として含有する殺虫、殺ダニ剤 |
| JPS5913793A (ja) * | 1982-07-15 | 1984-01-24 | Kanesho Kk | 有機リン酸エステル化合物及びその製造方法並にこれを有効成分として含有する殺虫、殺ダニ剤 |
| AT379253B (de) * | 1983-08-17 | 1985-12-10 | Bender & Co Gmbh | Verfahren und vorrichtung zum eluieren und dosieren eines radioaktiven nukleids |
| US5039863A (en) * | 1988-11-15 | 1991-08-13 | Ube Industries, Ltd. | Automatic radioisotope filling apparatus |
| GB9208386D0 (en) * | 1992-04-16 | 1992-06-03 | Amersham Int Plc | Storage and dispensing device for liquids |
| US5475232A (en) * | 1992-12-22 | 1995-12-12 | Syncor International Corp. | Method for elution of a radioisotope according to an elution run schedule |
| US7163031B2 (en) * | 2004-06-15 | 2007-01-16 | Mallinckrodt Inc. | Automated dispensing system and associated method of use |
| AU2006287838A1 (en) * | 2005-08-09 | 2007-03-15 | Mallinckrodt Inc. | Radioisotope generation system having partial elution capability |
| CA2724669C (en) * | 2008-06-11 | 2016-01-12 | Bracco Diagnostics Inc. | Cabinet structure configurations for infusion systems |
| US7862534B2 (en) * | 2008-06-11 | 2011-01-04 | Bracco Diagnostics Inc. | Infusion circuit subassemblies |
| US8317674B2 (en) * | 2008-06-11 | 2012-11-27 | Bracco Diagnostics Inc. | Shielding assemblies for infusion systems |
| US8708352B2 (en) | 2008-06-11 | 2014-04-29 | Bracco Diagnostics Inc. | Cabinet structure configurations for infusion systems |
| US9597053B2 (en) * | 2008-06-11 | 2017-03-21 | Bracco Diagnostics Inc. | Infusion systems including computer-facilitated maintenance and/or operation and methods of use |
| US8216181B2 (en) | 2008-11-19 | 2012-07-10 | Bracco Diagnostics, Inc. | Apparatus and methods for support of a membrane filter in a medical infusion system |
| AU2015229189B2 (en) | 2014-03-13 | 2020-04-09 | Bracco Diagnostics Inc. | Real time nuclear isotope detection |
| CN109563457A (zh) * | 2016-05-27 | 2019-04-02 | 生物梅里埃有限公司 | 在检测仪器之间运送试样容器的系统和方法 |
| RU2741629C2 (ru) | 2016-09-20 | 2021-01-28 | Бракко Дайэгностикс Инк. | Системы и способы производства, инфузионного ввода и контроля доставки радиоактивного изотопа |
| US12170153B2 (en) | 2018-03-28 | 2024-12-17 | Bracco Diagnostics Inc. | Systems and techniques for calibrating radioisotope delivery systems with a gamma detector |
| SG11202009326XA (en) | 2018-03-28 | 2020-10-29 | Bracco Diagnostics Inc | Early detection of radioisotope generator end life |
| CN115104159A (zh) | 2020-02-21 | 2022-09-23 | 布拉科诊断公司 | 放射性同位素发生器早期突破检测 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1051716A (OSRAM) * | 1962-07-02 | 1900-01-01 | ||
| US3774036A (en) * | 1972-02-23 | 1973-11-20 | Searle & Co | Generation of a supply of radionuclide |
-
1975
- 1975-06-16 US US587283A patent/US3997784A/en not_active Expired - Lifetime
-
1976
- 1976-06-02 AU AU14533/76A patent/AU1453376A/en not_active Expired
- 1976-06-09 CA CA254,395A patent/CA1046652A/en not_active Expired
- 1976-06-15 DK DK268076A patent/DK268076A/da unknown
- 1976-06-15 BR BR7603835A patent/BR7603835A/pt unknown
- 1976-06-15 FR FR7618108A patent/FR2315100A1/fr not_active Withdrawn
- 1976-06-15 SE SE7606789A patent/SE7606789L/xx unknown
- 1976-06-15 DD DD7600193378A patent/DD132546A5/xx unknown
- 1976-06-15 IT IT24331/76A patent/IT1081210B/it active
- 1976-06-15 BE BE167951A patent/BE842985A/xx unknown
- 1976-06-15 JP JP51069416A patent/JPS5286A/ja active Granted
- 1976-06-15 DE DE19762626802 patent/DE2626802A1/de active Pending
- 1976-06-15 IL IL49793A patent/IL49793A0/xx unknown
- 1976-06-15 NL NL7606467A patent/NL7606467A/xx not_active Application Discontinuation
- 1976-06-15 NO NO762070A patent/NO762070L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5715899B2 (OSRAM) | 1982-04-01 |
| FR2315100A1 (fr) | 1977-01-14 |
| JPS5286A (en) | 1977-01-05 |
| CA1046652A (en) | 1979-01-16 |
| IT1081210B (it) | 1985-05-16 |
| NL7606467A (nl) | 1976-12-20 |
| AU1453376A (en) | 1977-12-08 |
| IL49793A0 (en) | 1976-10-31 |
| BR7603835A (pt) | 1977-04-05 |
| US3997784A (en) | 1976-12-14 |
| DD132546A5 (de) | 1978-10-04 |
| SE7606789L (sv) | 1976-12-17 |
| DK268076A (da) | 1976-12-17 |
| BE842985A (fr) | 1976-12-15 |
| NO762070L (OSRAM) | 1976-12-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| OHN | Withdrawal |