DE2616615A1 - 2-geschweifte klammer auf 3- eckige klammer auf 4-azatricyclo(4.3.1.1 hoch 3,8) undecan-4-y1 eckige klammer zu -1,1-diphenylpropyl geschweifte klammer zu -5-methyl-1,3,4-oxadiazol und verwandte verbindungen - Google Patents
2-geschweifte klammer auf 3- eckige klammer auf 4-azatricyclo(4.3.1.1 hoch 3,8) undecan-4-y1 eckige klammer zu -1,1-diphenylpropyl geschweifte klammer zu -5-methyl-1,3,4-oxadiazol und verwandte verbindungenInfo
- Publication number
- DE2616615A1 DE2616615A1 DE19762616615 DE2616615A DE2616615A1 DE 2616615 A1 DE2616615 A1 DE 2616615A1 DE 19762616615 DE19762616615 DE 19762616615 DE 2616615 A DE2616615 A DE 2616615A DE 2616615 A1 DE2616615 A1 DE 2616615A1
- Authority
- DE
- Germany
- Prior art keywords
- azatricyclo
- undecan
- oxadiazole
- parts
- diphenylpropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 239000000243 solution Substances 0.000 claims description 62
- -1 undecan-4-yl Chemical group 0.000 claims description 23
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- 239000002904 solvent Substances 0.000 claims description 18
- VEUMBMHMMCOFAG-UHFFFAOYSA-N 2,3-dihydrooxadiazole Chemical compound N1NC=CO1 VEUMBMHMMCOFAG-UHFFFAOYSA-N 0.000 claims description 16
- 239000000725 suspension Substances 0.000 claims description 12
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- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 claims description 9
- 125000004432 carbon atom Chemical group C* 0.000 claims description 8
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- IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
- 125000004344 phenylpropyl group Chemical group 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
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- 229920001223 polyethylene glycol Polymers 0.000 description 1
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- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- WHYQCQRHPQBZHM-UHFFFAOYSA-N pyrazole-1-carboxylic acid Chemical compound OC(=O)N1C=CC=N1 WHYQCQRHPQBZHM-UHFFFAOYSA-N 0.000 description 1
- HNXBAIUPFRHZJH-UHFFFAOYSA-N pyrazole-1-carboxylic acid hydrochloride Chemical compound Cl.OC(=O)N1C=CC=N1 HNXBAIUPFRHZJH-UHFFFAOYSA-N 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 150000003385 sodium Chemical class 0.000 description 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 235000010356 sorbitol Nutrition 0.000 description 1
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- 239000008107 starch Substances 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
- 229960004793 sucrose Drugs 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- IIACRCGMVDHOTQ-UHFFFAOYSA-M sulfamate Chemical compound NS([O-])(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-M 0.000 description 1
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000006794 tachycardia Effects 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 238000002627 tracheal intubation Methods 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- WBYWAXJHAXSJNI-VOTSOKGWSA-M trans-cinnamate Chemical compound [O-]C(=O)\C=C\C1=CC=CC=C1 WBYWAXJHAXSJNI-VOTSOKGWSA-M 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
- 238000001665 trituration Methods 0.000 description 1
- 230000002861 ventricular Effects 0.000 description 1
- 239000005723 virus inoculator Substances 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05568405 USB568405I5 (enrdf_load_stackoverflow) | 1975-04-16 | 1975-04-16 | |
| US05/652,361 US4025524A (en) | 1975-04-16 | 1976-01-26 | 2-{3-[4-Azatricyclo(4.3.1.13,8)undecan-4-yl]-1,1-diphenylpropyl}-5-methyl-1,3,4-oxadiazole and congeners |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2616615A1 true DE2616615A1 (de) | 1976-10-28 |
Family
ID=27074780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19762616615 Withdrawn DE2616615A1 (de) | 1975-04-16 | 1976-04-15 | 2-geschweifte klammer auf 3- eckige klammer auf 4-azatricyclo(4.3.1.1 hoch 3,8) undecan-4-y1 eckige klammer zu -1,1-diphenylpropyl geschweifte klammer zu -5-methyl-1,3,4-oxadiazol und verwandte verbindungen |
Country Status (9)
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1498701A (enrdf_load_stackoverflow) * | 1965-10-04 | 1968-01-08 | ||
| US3917615A (en) * | 1974-04-01 | 1975-11-04 | Searle & Co | 1,1-Diaryl-1-oxadiazol-alkylamines |
-
1976
- 1976-01-26 US US05/652,361 patent/US4025524A/en not_active Expired - Lifetime
- 1976-04-14 ES ES447009A patent/ES447009A1/es not_active Expired
- 1976-04-15 SE SE7604474A patent/SE7604474L/xx unknown
- 1976-04-15 DE DE19762616615 patent/DE2616615A1/de not_active Withdrawn
- 1976-04-15 AU AU13044/76A patent/AU500456B2/en not_active Expired
- 1976-04-15 CA CA250,410A patent/CA1066275A/en not_active Expired
- 1976-04-15 FR FR7611235A patent/FR2307537A1/fr active Granted
- 1976-04-15 JP JP51043019A patent/JPS51127088A/ja active Pending
- 1976-04-15 GB GB15540/76A patent/GB1541652A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES447009A1 (es) | 1977-10-16 |
| FR2307537B1 (enrdf_load_stackoverflow) | 1979-09-28 |
| GB1541652A (en) | 1979-03-07 |
| JPS51127088A (en) | 1976-11-05 |
| SE7604474L (sv) | 1976-10-17 |
| CA1066275A (en) | 1979-11-13 |
| FR2307537A1 (fr) | 1976-11-12 |
| AU1304476A (en) | 1977-10-20 |
| US4025524A (en) | 1977-05-24 |
| AU500456B2 (en) | 1979-05-24 |
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