DE2552135A1 - 4-hydroperoxy-tetrahydro-2h- 1,3,2-oxazaphosphorin-2-oxid-derivate - Google Patents

4-hydroperoxy-tetrahydro-2h- 1,3,2-oxazaphosphorin-2-oxid-derivate

Info

Publication number
DE2552135A1
DE2552135A1 DE19752552135 DE2552135A DE2552135A1 DE 2552135 A1 DE2552135 A1 DE 2552135A1 DE 19752552135 DE19752552135 DE 19752552135 DE 2552135 A DE2552135 A DE 2552135A DE 2552135 A1 DE2552135 A1 DE 2552135A1
Authority
DE
Germany
Prior art keywords
oxazaphosphorine
tetrahydro
hydroperoxy
methyl
oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752552135
Other languages
German (de)
English (en)
Inventor
Tsuoyoshi Iwata
Akira Takamizawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Publication of DE2552135A1 publication Critical patent/DE2552135A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/14—Esters of phosphoric acids containing P(=O)-halide groups
    • C07F9/1403—Esters of phosphoric acids containing P(=O)-halide groups containing the structure Hal-P(=O)-O-unsaturated acyclic group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2412—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of unsaturated acyclic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19752552135 1974-11-20 1975-11-20 4-hydroperoxy-tetrahydro-2h- 1,3,2-oxazaphosphorin-2-oxid-derivate Withdrawn DE2552135A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49133257A JPS5159886A (enExample) 1974-11-20 1974-11-20

Publications (1)

Publication Number Publication Date
DE2552135A1 true DE2552135A1 (de) 1976-05-26

Family

ID=15100374

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752552135 Withdrawn DE2552135A1 (de) 1974-11-20 1975-11-20 4-hydroperoxy-tetrahydro-2h- 1,3,2-oxazaphosphorin-2-oxid-derivate

Country Status (9)

Country Link
JP (1) JPS5159886A (enExample)
AU (1) AU500813B2 (enExample)
CA (1) CA1051914A (enExample)
CH (1) CH602777A5 (enExample)
DE (1) DE2552135A1 (enExample)
FR (1) FR2291763A1 (enExample)
GB (1) GB1527497A (enExample)
NL (1) NL7513590A (enExample)
SE (1) SE7513007L (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2489825A1 (fr) * 1980-09-10 1982-03-12 Asta Werke Ag Chem Fab 4-carbamoyloxy-oxazaphosphorines, procede pour leur preparation et compositions pharmaceutiques qui les contiennent
US4716242A (en) * 1984-03-01 1987-12-29 Asta-Werke Aktiengesellschaft Chemische Fabrik Salts of oxazaphosphorine derivatives

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
JP4629238B2 (ja) * 1999-05-24 2011-02-09 サザン・リサーチ・インスティテュート イソホスホアミドマスタード・アナログ及びその使用
CA2585125C (en) 2004-10-25 2014-04-22 Lee Morgan Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents
US7964583B2 (en) 2006-02-17 2011-06-21 Ziopharm Oncology, Inc. Salts of isophosphoramide mustard and analogs thereof as anti-tumor agents
KR20150139620A (ko) 2007-04-06 2015-12-11 지오팜 온콜로지 인코포레이티드 이소포스포르아미드 머스타드의 염 및 이의 동족체

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2489825A1 (fr) * 1980-09-10 1982-03-12 Asta Werke Ag Chem Fab 4-carbamoyloxy-oxazaphosphorines, procede pour leur preparation et compositions pharmaceutiques qui les contiennent
US4716242A (en) * 1984-03-01 1987-12-29 Asta-Werke Aktiengesellschaft Chemische Fabrik Salts of oxazaphosphorine derivatives

Also Published As

Publication number Publication date
JPS5159886A (enExample) 1976-05-25
AU8681675A (en) 1977-05-26
CH602777A5 (enExample) 1978-07-31
AU500813B2 (en) 1979-05-10
NL7513590A (nl) 1976-05-24
FR2291763A1 (fr) 1976-06-18
SE7513007L (sv) 1976-05-21
GB1527497A (en) 1978-10-04
CA1051914A (en) 1979-04-03

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee