DE2537837A1 - Tetrahydropyridin- und piperidinderivate und verfahren zu ihrer herstellung - Google Patents

Tetrahydropyridin- und piperidinderivate und verfahren zu ihrer herstellung

Info

Publication number
DE2537837A1
DE2537837A1 DE19752537837 DE2537837A DE2537837A1 DE 2537837 A1 DE2537837 A1 DE 2537837A1 DE 19752537837 DE19752537837 DE 19752537837 DE 2537837 A DE2537837 A DE 2537837A DE 2537837 A1 DE2537837 A1 DE 2537837A1
Authority
DE
Germany
Prior art keywords
group
hydrogen
methyl
general formula
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19752537837
Other languages
German (de)
English (en)
Inventor
Raymond Dr Bernasconi
Karl Dr Schenker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of DE2537837A1 publication Critical patent/DE2537837A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE19752537837 1974-08-30 1975-08-26 Tetrahydropyridin- und piperidinderivate und verfahren zu ihrer herstellung Pending DE2537837A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1511677A CH609980A5 (en) 1974-08-30 1974-08-30 Process for the preparation of novel piperidine derivatives
CH1183774A CH605925A5 (fr) 1974-08-30 1974-08-30

Publications (1)

Publication Number Publication Date
DE2537837A1 true DE2537837A1 (de) 1976-03-18

Family

ID=25709012

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752537837 Pending DE2537837A1 (de) 1974-08-30 1975-08-26 Tetrahydropyridin- und piperidinderivate und verfahren zu ihrer herstellung

Country Status (11)

Country Link
JP (1) JPS5148673A (fr)
AT (1) AT348523B (fr)
AU (1) AU499372B2 (fr)
BE (1) BE832885A (fr)
CA (1) CA1076118A (fr)
CH (2) CH609980A5 (fr)
DE (1) DE2537837A1 (fr)
FR (1) FR2282887A1 (fr)
GB (1) GB1510977A (fr)
NL (1) NL7510142A (fr)
SE (1) SE7508897L (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006524A1 (fr) * 1978-06-22 1980-01-09 Ciba-Geigy Ag Dérivés de tétrahydropyridine et de tétrahydropipéridine, leurs sels d'addition acides, procédés pour leur préparation et compositions pharmaceutiques les contenant
US4447620A (en) * 1982-06-08 1984-05-08 The Upjohn Company Imidazolyl-substituted benzothiophenes
US4452986A (en) * 1982-06-08 1984-06-05 The Upjohn Company Imidazolyl-substituted benzofurans
US4455427A (en) * 1981-07-01 1984-06-19 The Upjohn Company Pyridyl-substituted-benzofurans
US4490531A (en) * 1981-07-01 1984-12-25 The Upjohn Company Pyridyl-substituted-benzofurans
US4495357A (en) * 1981-07-01 1985-01-22 The Upjohn Company Pyridyl-substituted-benzofurans
US4611059A (en) * 1982-10-12 1986-09-09 The Upjohn Company Pyridyl-substituted benzothiophenes
US4855435A (en) * 1982-10-12 1989-08-08 The Upjohn Company Pyridyl-substituted benzothiophenes

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU579647B2 (en) * 1985-02-21 1988-12-01 Asahi Kasei Kogyo Kabushiki Kaisha Process for adsorption treatment of dissolved fluorine
TW266206B (fr) * 1993-04-28 1995-12-21 Takeda Pharm Industry Co Ltd
US5891895A (en) * 1996-04-15 1999-04-06 Takeda Chemical Industries, Ltd. Hydroxypyridine derivatives their production and use

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0006524A1 (fr) * 1978-06-22 1980-01-09 Ciba-Geigy Ag Dérivés de tétrahydropyridine et de tétrahydropipéridine, leurs sels d'addition acides, procédés pour leur préparation et compositions pharmaceutiques les contenant
US4455427A (en) * 1981-07-01 1984-06-19 The Upjohn Company Pyridyl-substituted-benzofurans
US4490531A (en) * 1981-07-01 1984-12-25 The Upjohn Company Pyridyl-substituted-benzofurans
US4495357A (en) * 1981-07-01 1985-01-22 The Upjohn Company Pyridyl-substituted-benzofurans
US4447620A (en) * 1982-06-08 1984-05-08 The Upjohn Company Imidazolyl-substituted benzothiophenes
US4452986A (en) * 1982-06-08 1984-06-05 The Upjohn Company Imidazolyl-substituted benzofurans
US4611059A (en) * 1982-10-12 1986-09-09 The Upjohn Company Pyridyl-substituted benzothiophenes
US4855435A (en) * 1982-10-12 1989-08-08 The Upjohn Company Pyridyl-substituted benzothiophenes

Also Published As

Publication number Publication date
CH605925A5 (fr) 1978-10-13
AT348523B (de) 1979-02-26
FR2282887A1 (fr) 1976-03-26
NL7510142A (nl) 1976-03-02
SE7508897L (sv) 1976-03-01
CH609980A5 (en) 1979-03-30
CA1076118A (fr) 1980-04-22
ATA667875A (de) 1978-07-15
AU499372B2 (en) 1979-04-12
BE832885A (fr) 1976-03-01
JPS5148673A (fr) 1976-04-26
FR2282887B1 (fr) 1980-04-18
GB1510977A (en) 1978-05-17
AU8435675A (en) 1977-03-03

Similar Documents

Publication Publication Date Title
DE60023345T2 (de) Neue modulatoren der dopamin-neurotransmission
DE68906801T2 (de) 1,4-disubstituierte piperidin-verbindungen.
DE2627616A1 (de) Verfahren zur herstellung von neuen 2-piperidinoalkyl-1,4-benzodioxanen
DE60014043T2 (de) Flouride von 4-substituierten piperidin-derivaten
DE102004030099A1 (de) Gesättigte und ungesättigte 3-Pyridyl-benzocycloalkylmethyl-amine als Serotonin- und/oder Noradrenalin-Reuptake-Hemmer und/oder µ-Opioidrezeptor-Modulatoren
DE2537837A1 (de) Tetrahydropyridin- und piperidinderivate und verfahren zu ihrer herstellung
DE3002292C2 (fr)
CH637935A5 (de) Verfahren zur herstellung neuer derivate von perhydro-aza-heterocyclen.
EP0004358B1 (fr) N-oxacyclylalkylpipéridines, procédé pour leur préparation, compositions pharmaceutiques contenant ces composés
DE2408476C2 (fr)
DE60115997T2 (de) 1,1- und 1,2-disubstituierte Cyclopropane, Verfahren zu deren Herstellung und deren pharmazeutischen Zusammensetzungen
EP0000395B1 (fr) Dérivés de 2-pipérazinotétraline, leur préparation et leur utilisation comme médicament
DE69710909T2 (de) Substituierte tetrahydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
DE2653147C2 (fr)
DE1470055A1 (de) Verfahren zur Herstellung von Piperidinderivaten
EP0206155B1 (fr) Composés aromatiques, leur préparation et leur application
DE2802306A1 (de) Azacycloalkane, azacycloalkene und ihre derivate
DE2456246A1 (de) Neue benzothiophene und verfahren zu ihrer herstellung
AT340921B (de) Verfahren zur herstellung von neuen tetrahydropyridin- und piperidinderivaten und ihren saureadditionssalzen
CH613962A5 (en) Process for the preparation of novel piperidine derivatives
CH605926A5 (en) 2-(piperidino or tetrahydropyrido) benzofurans
CH613452A5 (en) Process for the preparation of novel tetrahydropyridine derivatives
CH613961A5 (en) Process for the preparation of novel tetrahydropyridine and piperidine derivatives
AT340923B (de) Verfahren zur herstellung von neuen tetrahydropyridin- und piperidinderivaten und ihren saureadditionssalzen
CH605927A5 (en) 2-(piperidino or tetrahydropyrido) benzofurans

Legal Events

Date Code Title Description
OHN Withdrawal