DE2414623A1 - Amidderivate von nicotinsaeure - Google Patents

Amidderivate von nicotinsaeure

Info

Publication number
DE2414623A1
DE2414623A1 DE2414623A DE2414623A DE2414623A1 DE 2414623 A1 DE2414623 A1 DE 2414623A1 DE 2414623 A DE2414623 A DE 2414623A DE 2414623 A DE2414623 A DE 2414623A DE 2414623 A1 DE2414623 A1 DE 2414623A1
Authority
DE
Germany
Prior art keywords
general formula
noted
carried out
amide derivatives
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE2414623A
Other languages
German (de)
English (en)
Inventor
Claudio Cavazza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IT7348674A priority Critical patent/IT1056031B/it
Priority to GB1196774A priority patent/GB1455169A/en
Priority to JP49033059A priority patent/JPS50126669A/ja
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority to DE2414623A priority patent/DE2414623A1/de
Priority to FR7411338A priority patent/FR2220272B1/fr
Publication of DE2414623A1 publication Critical patent/DE2414623A1/de
Priority to US05/668,498 priority patent/US4021433A/en
Priority claimed from US05/668,498 external-priority patent/US4021433A/en
Priority to US05/754,525 priority patent/US4100289A/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/04—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE2414623A 1973-03-08 1974-03-26 Amidderivate von nicotinsaeure Ceased DE2414623A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT7348674A IT1056031B (it) 1973-03-08 1973-03-08 Redivati ammidici dell acido nicotininico
GB1196774A GB1455169A (en) 1973-03-08 1974-03-18 Amidic derivatives of nicotinic acid
JP49033059A JPS50126669A (enExample) 1973-03-08 1974-03-22
DE2414623A DE2414623A1 (de) 1973-03-08 1974-03-26 Amidderivate von nicotinsaeure
FR7411338A FR2220272B1 (enExample) 1973-03-08 1974-03-29
US05/668,498 US4021433A (en) 1973-03-08 1976-03-19 Derivative of nicotinic acid with amides
US05/754,525 US4100289A (en) 1973-03-08 1976-12-27 Amidic derivatives of nicotinic acid as therapeutics

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IT7348674A IT1056031B (it) 1973-03-08 1973-03-08 Redivati ammidici dell acido nicotininico
GB1196774A GB1455169A (en) 1973-03-08 1974-03-18 Amidic derivatives of nicotinic acid
JP49033059A JPS50126669A (enExample) 1973-03-08 1974-03-22
DE2414623A DE2414623A1 (de) 1973-03-08 1974-03-26 Amidderivate von nicotinsaeure
US05/668,498 US4021433A (en) 1973-03-08 1976-03-19 Derivative of nicotinic acid with amides

Publications (1)

Publication Number Publication Date
DE2414623A1 true DE2414623A1 (de) 1975-10-16

Family

ID=32996413

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2414623A Ceased DE2414623A1 (de) 1973-03-08 1974-03-26 Amidderivate von nicotinsaeure

Country Status (6)

Country Link
US (1) US4100289A (enExample)
JP (1) JPS50126669A (enExample)
DE (1) DE2414623A1 (enExample)
FR (1) FR2220272B1 (enExample)
GB (1) GB1455169A (enExample)
IT (1) IT1056031B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5350178A (en) * 1976-10-14 1978-05-08 Sigma Tau Ind Farmaceuti Production of nn66 chloronicotynoyl homocysteine thiolactone
DE3600712A1 (de) * 1985-01-17 1986-07-17 Daicel Chemical Industries, Ltd., Sakai, Osaka 5-halopyridin-3-carboxamidverbindungen
DE3601121A1 (de) * 1985-01-18 1986-08-21 Daicel Chemical Industries, Ltd., Sakai, Osaka 4-substituierte-oxy-3-pyridincarboxamide

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155672A (en) * 1964-11-03 N-diphenylisomcotinamide
SU516354A3 (ru) * 1970-03-07 1976-05-30 Краковски Заклады Фармацеутичне"Польфа" (Инопредприятие) Способ получени пиридиламидов фуранкарбоновой кислоты или их солей

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5350178A (en) * 1976-10-14 1978-05-08 Sigma Tau Ind Farmaceuti Production of nn66 chloronicotynoyl homocysteine thiolactone
DE3600712A1 (de) * 1985-01-17 1986-07-17 Daicel Chemical Industries, Ltd., Sakai, Osaka 5-halopyridin-3-carboxamidverbindungen
DE3601121A1 (de) * 1985-01-18 1986-08-21 Daicel Chemical Industries, Ltd., Sakai, Osaka 4-substituierte-oxy-3-pyridincarboxamide

Also Published As

Publication number Publication date
GB1455169A (en) 1976-11-10
JPS50126669A (enExample) 1975-10-04
IT1056031B (it) 1982-01-30
FR2220272B1 (enExample) 1977-05-06
FR2220272A1 (enExample) 1974-10-04
US4100289A (en) 1978-07-11

Similar Documents

Publication Publication Date Title
DE69213720T2 (de) VERFAHREN ZUR HERSTELLUNG VON IMIDAZO (4,5-c) CHINOLIN-4-AMINEN
DE3001328C2 (enExample)
DE2065236B2 (de) Phosphonsäuresalze, ihre Herstellung und Verwendung
DE2407115A1 (de) Neue 1,4-dihydropyridinderivate
DE3209276A1 (de) Arzneimittel mit antihypoxischer und ischaemie-protektiver wirkung
DE2311131C3 (de) Amidinopenicillansäureester, Verfahren zu deren Herstellung und pharmazeutische Mittel
DE2265169C3 (de) Vincaminsäureäthylester, Herstellungsverfahren und pharmazeutische Mittel
DE2726754A1 (de) Substituierte (3-niedrigalkylamino- 2-acyl-0-propoxy)-pyridine, verfahren zu ihrer herstellung und ihre verwendung
DE2414623A1 (de) Amidderivate von nicotinsaeure
EP0693071B1 (de) Neue carbonsäureester von 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren herstellung sowie deren verwendung
EP0166296B1 (de) Verfahren zur Herstellung optisch aktiver 1,4-Dihydropyridine
DE2414621A1 (de) Heterocyclische amidderivate von nicotinsaeure mit wenigstens einem stickstoffund einem schwefelatom in dem heterozyklus
DE2520131C3 (de) 1,1,-Disubstituierte Octahydro-indolo[2,3-a]chinolizine und verfahren zu deren Herstellung
DE2521104B2 (de) 4-Aryl-aminoalkyl-4-thiazolin-2-one, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
CH645623A5 (en) 2-Methyl-3-acetoxy-4,5-bis(halomethyl)pyridines, process for their preparation and process for the preparation of pyridoxin
DE2238923A1 (de) Acylierte n(6)-aralkyl-adenosinderivate und verfahren zur herstellung derselben
DE2828888C2 (enExample)
EP0657430B1 (de) Isopropyl-(2-methoxyethyl)-4-(2-chlor-3-cyano-phenyl)-1,4-dihydro-2,6-dimethyl-pyridin-3,5-dicarboxylat
DE69127238T2 (de) Verfahren zur Herstellung von Pyrido[1,2-a]pyrimidinderivaten
DE2362687A1 (de) Verfahren zur razematspaltung von d,l-penicillamin
DE2414622A1 (de) Derivate der nicotinsaeure mit verschieden substituierten aminen
DE2523208C3 (de) Thienylessigsäureester, ein Verfahren zu ihrer Herstellung sowie Arzneimittel
DE4100125A1 (de) Neue dihydropyridinamide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE2419535C3 (de) 6-Aminonicotinsäureamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE1695554B2 (de) Verfahren zur herstellung kondensierter piperazinonderivate

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection