DE2401254A1 - Neue derivate von n hoch 6-substituierten adeninen - Google Patents

Neue derivate von n hoch 6-substituierten adeninen

Info

Publication number
DE2401254A1
DE2401254A1 DE2401254A DE2401254A DE2401254A1 DE 2401254 A1 DE2401254 A1 DE 2401254A1 DE 2401254 A DE2401254 A DE 2401254A DE 2401254 A DE2401254 A DE 2401254A DE 2401254 A1 DE2401254 A1 DE 2401254A1
Authority
DE
Germany
Prior art keywords
adenine
general formula
phenyl
propyl
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE2401254A
Other languages
German (de)
English (en)
Inventor
Walter-Gunar Dr Rer Nat Friebe
Androniki Dr Med Roesch
Wolfgang Prof Dr Med Schaumann
Max Dr Rer Nat Thiel
Werner Dr Rer Nat Winter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE2401254A priority Critical patent/DE2401254A1/de
Priority to US05/531,420 priority patent/US3996361A/en
Priority to AU77019/74A priority patent/AU479786B2/en
Priority to AR260900A priority patent/AR206360A1/es
Priority to AR257216A priority patent/AR206336A1/es
Priority to CA217,318A priority patent/CA1036595A/en
Priority to RO7581042A priority patent/RO66908A/ro
Priority to RO7591006A priority patent/RO70740A/ro
Priority to BG028654A priority patent/BG25996A3/xx
Priority to BG031111A priority patent/BG24230A3/xx
Priority to FI750019A priority patent/FI750019A7/fi
Priority to NL7500094A priority patent/NL7500094A/xx
Priority to GB38575A priority patent/GB1436533A/en
Priority to CH2375A priority patent/CH594670A5/xx
Priority to DD183515A priority patent/DD117222A5/xx
Priority to BE152172A priority patent/BE824133A/xx
Priority to CS7500000107A priority patent/CS185572B2/cs
Priority to SE7500104A priority patent/SE413407B/xx
Priority to DK3575A priority patent/DK135424C/da
Priority to ES433680A priority patent/ES433680A1/es
Priority to AT11575*#A priority patent/AT334390B/de
Priority to AT87576*#A priority patent/AT334393B/de
Priority to PL1975177263A priority patent/PL93396B1/pl
Priority to JP50005533A priority patent/JPS50101385A/ja
Priority to ZA00750179A priority patent/ZA75179B/xx
Priority to SU7502096069A priority patent/SU571192A3/ru
Priority to HUBO1530A priority patent/HU168488B/hu
Priority to PL1975187102A priority patent/PL94634B1/pl
Priority to FR7500689A priority patent/FR2257296B1/fr
Publication of DE2401254A1 publication Critical patent/DE2401254A1/de
Priority to SU762310704A priority patent/SU614750A3/ru
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2401254A 1974-01-11 1974-01-11 Neue derivate von n hoch 6-substituierten adeninen Withdrawn DE2401254A1 (de)

Priority Applications (30)

Application Number Priority Date Filing Date Title
DE2401254A DE2401254A1 (de) 1974-01-11 1974-01-11 Neue derivate von n hoch 6-substituierten adeninen
US05/531,420 US3996361A (en) 1974-01-11 1974-12-10 N6 -Substituted-9-[3-(4-phenyl-piperazino)-propyl]-adenines
AU77019/74A AU479786B2 (en) 1974-12-31 New arylipiperazine derivatives of adenine and the preparation thereof
AR260900A AR206360A1 (es) 1974-01-11 1975-01-01 Procedimiento para la preparacion de derivados de 9-(3-(4-fenil piperazino)-propil)-adenina
AR257216A AR206336A1 (es) 1974-01-11 1975-01-01 Procedimiento para la preparacion de derivados de 9-(3-(4-fenil-piperazino)-propil)-adenia
CA217,318A CA1036595A (en) 1974-01-11 1975-01-03 Arylpiperazine derivatives of adenine
RO7581042A RO66908A (ro) 1974-01-11 1975-01-04 Procedeu de preparare a unor 9(3-(4-fenilpiperazino)-propil)-adenine
RO7591006A RO70740A (ro) 1974-01-11 1975-01-04 Procedeu de preparare a unor 9-(3-(4-fenilpipe-razino)-propil-adenine
BG028654A BG25996A3 (bg) 1974-01-11 1975-01-04 Метод за получаване на арилпиперазинови производни на аденина
BG031111A BG24230A3 (bg) 1974-01-11 1975-01-04 Метод за получаване на арилпиперазинови производни на аденин
BE152172A BE824133A (fr) 1974-01-11 1975-01-06 Nouveaux derives d'adenines n6-substituees et procedes de preparation
NL7500094A NL7500094A (nl) 1974-01-11 1975-01-06 Arylpiperazinederivaten van adenine.
GB38575A GB1436533A (en) 1974-01-11 1975-01-06 Aryl piperazine derivatives of adenine
CH2375A CH594670A5 (enEXAMPLES) 1974-01-11 1975-01-06
DD183515A DD117222A5 (enEXAMPLES) 1974-01-11 1975-01-06
FI750019A FI750019A7 (enEXAMPLES) 1974-01-11 1975-01-06
CS7500000107A CS185572B2 (en) 1974-01-11 1975-01-07 Process for preparing arylpiperazine derivatives of adenine
SE7500104A SE413407B (sv) 1974-01-11 1975-01-07 Forfarande for framstellning av n?726-substituerade adeniner
DK3575A DK135424C (da) 1974-01-11 1975-01-08 Analogifremgangsmade til fremstilling af arylpiperazinderivater af adenin
AT87576*#A AT334393B (de) 1974-01-11 1975-01-09 Verfahren zur herstellung von neuen 9- (3- (4-phenylpiperazino) -propyl) -adeninen und ihren saureadditionssalzen
AT11575*#A AT334390B (de) 1974-01-11 1975-01-09 Verfahren zur herstellung von neuen 9-(3-(4-phenylpiperazino)-propyl)-adeninen und ihren saureadditonssalzen
ES433680A ES433680A1 (es) 1974-01-11 1975-01-09 Procedimiento para la preparacion de derivados de arilpipe-razinicos de la adenina.
PL1975177263A PL93396B1 (enEXAMPLES) 1974-01-11 1975-01-10
JP50005533A JPS50101385A (enEXAMPLES) 1974-01-11 1975-01-10
ZA00750179A ZA75179B (en) 1974-01-11 1975-01-10 New arylpiperazine derivatives of adenine and the preparation thereof
SU7502096069A SU571192A3 (ru) 1974-01-11 1975-01-10 Способ получени арилпиперазиновых производных аденина
HUBO1530A HU168488B (enEXAMPLES) 1974-01-11 1975-01-10
PL1975187102A PL94634B1 (pl) 1974-01-11 1975-01-10 Sposob wytwarzania nowych arylopiperazynowych pochodnych adeniny
FR7500689A FR2257296B1 (enEXAMPLES) 1974-01-11 1975-01-10
SU762310704A SU614750A3 (ru) 1974-01-11 1976-01-09 Способ получени арилпиперазиновых производных аденина или их солей

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2401254A DE2401254A1 (de) 1974-01-11 1974-01-11 Neue derivate von n hoch 6-substituierten adeninen

Publications (1)

Publication Number Publication Date
DE2401254A1 true DE2401254A1 (de) 1975-11-27

Family

ID=5904603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2401254A Withdrawn DE2401254A1 (de) 1974-01-11 1974-01-11 Neue derivate von n hoch 6-substituierten adeninen

Country Status (23)

Country Link
US (1) US3996361A (enEXAMPLES)
JP (1) JPS50101385A (enEXAMPLES)
AR (2) AR206360A1 (enEXAMPLES)
AT (2) AT334390B (enEXAMPLES)
BE (1) BE824133A (enEXAMPLES)
BG (2) BG25996A3 (enEXAMPLES)
CA (1) CA1036595A (enEXAMPLES)
CH (1) CH594670A5 (enEXAMPLES)
CS (1) CS185572B2 (enEXAMPLES)
DD (1) DD117222A5 (enEXAMPLES)
DE (1) DE2401254A1 (enEXAMPLES)
DK (1) DK135424C (enEXAMPLES)
ES (1) ES433680A1 (enEXAMPLES)
FI (1) FI750019A7 (enEXAMPLES)
FR (1) FR2257296B1 (enEXAMPLES)
GB (1) GB1436533A (enEXAMPLES)
HU (1) HU168488B (enEXAMPLES)
NL (1) NL7500094A (enEXAMPLES)
PL (2) PL93396B1 (enEXAMPLES)
RO (2) RO70740A (enEXAMPLES)
SE (1) SE413407B (enEXAMPLES)
SU (2) SU571192A3 (enEXAMPLES)
ZA (1) ZA75179B (enEXAMPLES)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2549999A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Piperidin-derivate und verfahren zu ihrer herstellung
DE2550000A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Neue purin-derivate und verfahren zu ihrer herstellung
DE2804416A1 (de) * 1978-02-02 1979-08-09 Boehringer Mannheim Gmbh Neue purin-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
JPS55118488A (en) * 1979-03-05 1980-09-11 Eisai Co Ltd Theobromine derivative and its preparation
DE2922159A1 (de) * 1979-05-31 1980-12-04 Boehringer Mannheim Gmbh Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
HU198052B (en) * 1986-02-14 1989-07-28 Sandoz Ag Process for producing purine derivatives substituted by side chain containing piperazinyl ring and pharmaceutical compositions comprising such compounds
US5057517A (en) * 1987-07-20 1991-10-15 Merck & Co., Inc. Piperazinyl derivatives of purines and isosteres thereof as hypoglycemic agents
WO2001049688A1 (en) * 2000-01-07 2001-07-12 Universitaire Instelling Antwerpen Purine derivatives, process for their preparation and use thereof
EP1764134B1 (en) * 2001-07-30 2009-01-28 Spectrum Pharmaceuticals, Inc. Purine derivatives linked to arylpiperazines
CZ294535B6 (cs) * 2001-08-02 2005-01-12 Ústav Experimentální Botaniky Avčr Heterocyklické sloučeniny na bázi N6-substituovaného adeninu, způsoby jejich přípravy, jejich použití pro přípravu léčiv, kosmetických přípravků a růstových regulátorů, farmaceutické přípravky, kosmetické přípravky a růstové regulátory tyto sloučeniny obsahující
GB0224084D0 (en) * 2002-10-16 2002-11-27 Glaxo Group Ltd Novel compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE621979R (fr) * 1962-08-31 1963-02-28 Rene A H Denayer Procédé de préparation de dérivés de l'adénine
GB1165283A (en) * 1967-01-17 1969-09-24 Science Union & Cie New Purine Derivatives and processes for prepararing them
DE2245061A1 (de) * 1972-09-14 1974-03-28 Boehringer Mannheim Gmbh Derivate des adenins
US3862189A (en) * 1973-08-14 1975-01-21 Warner Lambert Co Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents

Also Published As

Publication number Publication date
RO66908A (ro) 1982-09-09
GB1436533A (en) 1976-05-19
AT334390B (de) 1976-01-10
DK3575A (enEXAMPLES) 1975-08-25
DD117222A5 (enEXAMPLES) 1976-01-05
SE413407B (sv) 1980-05-27
CS185572B2 (en) 1978-10-31
ES433680A1 (es) 1976-12-01
ATA11575A (de) 1976-05-15
SU614750A3 (ru) 1978-07-05
BE824133A (fr) 1975-07-07
RO70740A (ro) 1982-10-26
AU7701974A (en) 1976-07-01
SE7500104L (enEXAMPLES) 1975-07-14
BG25996A3 (bg) 1979-01-12
DK135424C (da) 1977-10-10
JPS50101385A (enEXAMPLES) 1975-08-11
BG24230A3 (bg) 1978-01-10
ATA87576A (de) 1976-05-15
CH594670A5 (enEXAMPLES) 1978-01-13
PL93396B1 (enEXAMPLES) 1977-05-30
FI750019A7 (enEXAMPLES) 1975-07-12
HU168488B (enEXAMPLES) 1976-05-28
AR206360A1 (es) 1976-07-15
PL94634B1 (pl) 1977-08-31
DK135424B (da) 1977-04-25
US3996361A (en) 1976-12-07
NL7500094A (nl) 1975-07-15
FR2257296A1 (enEXAMPLES) 1975-08-08
ZA75179B (en) 1976-02-25
CA1036595A (en) 1978-08-15
SU571192A3 (ru) 1977-08-30
AT334393B (de) 1977-01-10
FR2257296B1 (enEXAMPLES) 1980-01-04
AR206336A1 (es) 1976-07-15

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination