DE2365719A1 - Arabinofuranosyl-6-azacytosine und verfahren zu ihrer herstellung - Google Patents

Arabinofuranosyl-6-azacytosine und verfahren zu ihrer herstellung

Info

Publication number
DE2365719A1
DE2365719A1 DE2365719*A DE2365719A DE2365719A1 DE 2365719 A1 DE2365719 A1 DE 2365719A1 DE 2365719 A DE2365719 A DE 2365719A DE 2365719 A1 DE2365719 A1 DE 2365719A1
Authority
DE
Germany
Prior art keywords
acyl
chloride
arabinofuranosyl
pharmaceutically acceptable
azacytosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2365719*A
Other languages
German (de)
English (en)
Inventor
John G Moffat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of DE2365719A1 publication Critical patent/DE2365719A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2365719*A 1972-03-03 1973-03-01 Arabinofuranosyl-6-azacytosine und verfahren zu ihrer herstellung Pending DE2365719A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/231,754 US3998807A (en) 1972-03-03 1972-03-03 Arabinofuranosyl cytosines and methods of making

Publications (1)

Publication Number Publication Date
DE2365719A1 true DE2365719A1 (de) 1976-01-29

Family

ID=22870525

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2365719*A Pending DE2365719A1 (de) 1972-03-03 1973-03-01 Arabinofuranosyl-6-azacytosine und verfahren zu ihrer herstellung
DE19732310329 Pending DE2310329A1 (de) 1972-03-03 1973-03-01 Arabinofuranosylcytosine und verfahren zu ihrer herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19732310329 Pending DE2310329A1 (de) 1972-03-03 1973-03-01 Arabinofuranosylcytosine und verfahren zu ihrer herstellung

Country Status (9)

Country Link
US (1) US3998807A (US07754267-20100713-C00021.png)
JP (1) JPS4992078A (US07754267-20100713-C00021.png)
CH (2) CH583249A5 (US07754267-20100713-C00021.png)
DE (2) DE2365719A1 (US07754267-20100713-C00021.png)
ES (2) ES412270A1 (US07754267-20100713-C00021.png)
FR (1) FR2181780B1 (US07754267-20100713-C00021.png)
GB (2) GB1427572A (US07754267-20100713-C00021.png)
NL (1) NL7303000A (US07754267-20100713-C00021.png)
SE (2) SE399560B (US07754267-20100713-C00021.png)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5159880A (en) * 1974-11-22 1976-05-25 Asahi Chemical Ind N44 ashirunukureoshidojikarubonsanesuteruno seiho
US4267171A (en) * 1979-07-02 1981-05-12 The Regents Of The University Of California C-5 Substituted cytosine nucleosides
JPS5639019A (en) * 1979-09-05 1981-04-14 Yamasa Shoyu Co Ltd Antiviral agent
US4684630A (en) * 1983-08-24 1987-08-04 Repta Arnold J Method of parenterally delivering drugs and related compositions
GB9307043D0 (en) * 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
US6551210B2 (en) * 2000-10-24 2003-04-22 Motion Technologies, Llc. Continuously variable transmission
TWI332507B (en) * 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives
CN1742018A (zh) * 2002-12-10 2006-03-01 弗·哈夫曼-拉罗切有限公司 抗病毒的核苷衍生物
AU2008304381A1 (en) * 2007-09-26 2009-04-02 Clavis Pharma Asa Azacytidine analogues and uses thereof
ES2382588T3 (es) * 2008-11-05 2012-06-11 Cognis Ip Management Gmbh Procedimiento para la preparación de pro-fármacos de acyclovir

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155646A (en) * 1960-08-23 1964-11-03 Upjohn Co 1-arabinofuranosyl-5-halouracil and process for the preparation thereof
GB1070413A (en) * 1962-11-15 1967-06-01 Sankyo Co A process for preparing purine and pyrimidine nucleosides
US3328388A (en) * 1964-09-02 1967-06-27 Merck & Co Inc Arabinofuranosyl pyrimidines and methods of preparing same
US3338882A (en) * 1965-06-28 1967-08-29 Upjohn Co 2'-and 3'-phosphates of 1-beta-d-arabinofuranosylcytosine
US3463850A (en) * 1967-01-03 1969-08-26 Merck & Co Inc Arabinofuranosyl 2-thiopyrimidines and pharmaceutical compositions thereof
US3658788A (en) * 1969-06-06 1972-04-25 Salk Inst For Biological Studi Aminooxazolines and products thereof and processes for synthesizing same
US3755296A (en) * 1969-07-24 1973-08-28 Kohjin Co Process for preparing 1-{62 -d-arabinofuranosyl-cytosine and 2,2{40 -cyclocytidine
US3709874A (en) * 1970-03-19 1973-01-09 Syntex Corp 1-beta-d-arabinofuranosyl cytosine derivatives and methods of preparing
GB1322136A (en) * 1971-01-27 1973-07-04 Upjohn Co Ara-cytidine derivatives
US3894000A (en) * 1971-01-27 1975-07-08 Upjohn Co Ara-cytidine derivatives and process of preparation

Also Published As

Publication number Publication date
NL7303000A (US07754267-20100713-C00021.png) 1973-09-06
JPS4992078A (US07754267-20100713-C00021.png) 1974-09-03
DE2310329A1 (de) 1973-09-20
ES412270A1 (es) 1976-10-16
AU5274373A (en) 1974-09-05
FR2181780A1 (US07754267-20100713-C00021.png) 1973-12-07
SE399560B (sv) 1978-02-20
ES441538A1 (es) 1977-04-01
CH585766A5 (US07754267-20100713-C00021.png) 1977-03-15
SE7604155L (sv) 1976-04-08
US3998807A (en) 1976-12-21
GB1427571A (en) 1976-03-10
GB1427572A (en) 1976-03-10
CH583249A5 (US07754267-20100713-C00021.png) 1976-12-31
FR2181780B1 (US07754267-20100713-C00021.png) 1977-07-01

Similar Documents

Publication Publication Date Title
EP0316704B1 (de) Fluorcytidinderivate, deren Herstellung und Arzneimittel, die diese Derivate enthalten
DE2756653C2 (de) 5'-Deoxy-5-fluorcytidin und 5'- Deoxy-5-fluoruridin, deren Isopropylidenderivate und Salze und Verfahren zu deren Herstellung
DE2923368C2 (US07754267-20100713-C00021.png)
DE2332485C2 (de) Gentamicin C1-derivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2166717A1 (de) Verfahren zur herstellung von arabinofuranosylverbindungen
DE2365719A1 (de) Arabinofuranosyl-6-azacytosine und verfahren zu ihrer herstellung
DE2025624C2 (de) 5'-0-Ester von ara-Cytidin und Verfahren zu ihrer Herstellung
DE3390162T1 (de) Desoxyuridinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika
DE2502296C2 (de) 1-N-(S)-3-Amino-2-hydroxypropionyl- und 1-N-(S)-4-Amino-2-hydroxybutyryl-substituierte 4,6-Di-(aminoglycosyl)-1,3-diaminocyclitole und deren Salze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DE2515630C2 (de) 4-0-(6-Amino-6-desoxy-alpha-D-glucopyranosyl)-5-0[3-0(2,6-diamino-2,6-didesoxy-ß-L-idophyranosyl)-ß-D-ribofuranosyl]-2-desoxy-streptamin, Verfahren zu seiner Herstellung und diese Verbindung enthaltende Arzneimittel
DE2537375A1 (de) 9,3'',4''-triacylester des antibiotikums sf-837 m tief 1 sowie verfahren zur herstellung derselben
DE2035573A1 (de) Neue Imidazolderivate, ihre Herstellung und die sie enthaltenden medizinischen Zu sammensetzungen
DE2361159C3 (de) 3'-Desoxy-neamin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2612287A1 (de) Aminoglykosid-antibiotika, verfahren zu ihrer herstellung und sie enthaltende arzneimittelzubereitungen
EP0313935B1 (de) Enolether von 6-Chlor-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno(2,3-e)-1,2-thiazin-3-carbonsäureamid-1,1-dioxid, ein Verfahren zu ihrer Herstellung sowie ihre Verwendung
DE68928127T2 (de) 2'-Methylidenpyrimidinnukleosidverbindungen, ihre Verwendung und Verfahren zu ihrer Herstellung
DE2156637A1 (de) Purinzuckerderivate, Verfahren zu ihrer Herstellung und ihrer Verwendung
DE69915327T2 (de) Derivate des erythromycins, des clarithromycins, des roxithromycins oder des azithromycin mit antibiotischer und mucolytischer wirkung
DE1804983A1 (de) Verfahren zur Herstellung von Cephalosporansaeurederivaten
DE2121648B2 (de) Monoacetate der Antibiotica SF-837 und SF 83 7-A tief 2
DE3428945A1 (de) 4'-halogenanthracyclinglykoside, verfahren zu deren herstellung und diese enthaltende pharmazeutische zubereitung
DE68920304T2 (de) 5-substituierte uridinderivate und zwischenprodukte.
DE2511829C2 (US07754267-20100713-C00021.png)
DE2316705B2 (de) 9-Acyl-3' '-thiomethoxymethyl-SF-837-Macrolid-Antibiotika, Verfahren zur Herstellung derselben sowie diese enthaltende pharmazeutische MIttel
DE3306505C2 (de) 4-Desmethoxy-13-dihydro-daunorubicin, Verfahren zu dessen Herstellung und diese Verbindung enthaltende Arzneimittel

Legal Events

Date Code Title Description
OHN Withdrawal