DE2332065C2 - Verfahren zur Herstellung von Cephalosporinen sowie deren N-Alkoxycarbonyl- oder N-Arylcarbamoylderivaten - Google Patents

Verfahren zur Herstellung von Cephalosporinen sowie deren N-Alkoxycarbonyl- oder N-Arylcarbamoylderivaten

Info

Publication number
DE2332065C2
DE2332065C2 DE19732332065 DE2332065A DE2332065C2 DE 2332065 C2 DE2332065 C2 DE 2332065C2 DE 19732332065 DE19732332065 DE 19732332065 DE 2332065 A DE2332065 A DE 2332065A DE 2332065 C2 DE2332065 C2 DE 2332065C2
Authority
DE
Germany
Prior art keywords
solution
ethyl acetate
adjusted
active material
multiples
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19732332065
Other languages
German (de)
English (en)
Other versions
DE2332065A1 (de
Inventor
Junzi Ikeda Hosoda
Hiroshi Imanaka
Kazuyoshi Kawanishi Jomon
Daizou Hatsutoriyutakamachi Morino
Heiichi Ikeda Sakai
Ikuo Yao Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6462472A external-priority patent/JPS552959B2/ja
Priority claimed from JP6856972A external-priority patent/JPS5628520B2/ja
Priority claimed from JP7322372A external-priority patent/JPS5443080B2/ja
Priority claimed from JP1630373A external-priority patent/JPS5529680B2/ja
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE2332065A1 publication Critical patent/DE2332065A1/de
Application granted granted Critical
Publication of DE2332065C2 publication Critical patent/DE2332065C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/08—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin disubstituted in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
DE19732332065 1972-06-27 1973-06-23 Verfahren zur Herstellung von Cephalosporinen sowie deren N-Alkoxycarbonyl- oder N-Arylcarbamoylderivaten Expired DE2332065C2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP6462472A JPS552959B2 (enExample) 1972-06-27 1972-06-27
JP6856972A JPS5628520B2 (enExample) 1972-07-07 1972-07-07
JP7322372A JPS5443080B2 (enExample) 1972-07-20 1972-07-20
JP1630373A JPS5529680B2 (enExample) 1973-02-08 1973-02-08

Publications (2)

Publication Number Publication Date
DE2332065A1 DE2332065A1 (de) 1974-01-17
DE2332065C2 true DE2332065C2 (de) 1984-11-22

Family

ID=27456549

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19732332065 Expired DE2332065C2 (de) 1972-06-27 1973-06-23 Verfahren zur Herstellung von Cephalosporinen sowie deren N-Alkoxycarbonyl- oder N-Arylcarbamoylderivaten

Country Status (5)

Country Link
CH (2) CH596308A5 (enExample)
DE (1) DE2332065C2 (enExample)
FR (1) FR2190420B1 (enExample)
GB (1) GB1425081A (enExample)
NL (1) NL7308948A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198503A (en) 1974-11-05 1980-04-15 Beecham Group Limited 3-Carbamoyl substituted-7-ureido substituted cephalosporins
EP0095320A1 (en) * 1982-05-21 1983-11-30 Beecham Group Plc A process for the preparation of beta-lactam compounds
CN1795197B (zh) 2003-05-28 2010-06-02 帝斯曼知识产权资产管理有限公司 头孢菌素类化合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK143030C (da) * 1968-07-01 1981-10-12 Bristol Myers Co Fremgangsmaade til in situ fremstilling af et cephalosporin c-derivat

Also Published As

Publication number Publication date
FR2190420B1 (enExample) 1977-07-15
FR2190420A1 (enExample) 1974-02-01
CH596227A5 (enExample) 1978-03-15
DE2332065A1 (de) 1974-01-17
GB1425081A (en) 1976-02-18
NL7308948A (enExample) 1974-01-02
CH596308A5 (enExample) 1978-03-15

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Legal Events

Date Code Title Description
OD Request for examination
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee