DE2318137A1 - Mittel fuer augen beziehungsweise kontaktlinsen - Google Patents
Mittel fuer augen beziehungsweise kontaktlinsenInfo
- Publication number
- DE2318137A1 DE2318137A1 DE2318137A DE2318137A DE2318137A1 DE 2318137 A1 DE2318137 A1 DE 2318137A1 DE 2318137 A DE2318137 A DE 2318137A DE 2318137 A DE2318137 A DE 2318137A DE 2318137 A1 DE2318137 A1 DE 2318137A1
- Authority
- DE
- Germany
- Prior art keywords
- diguanide
- composition according
- eye
- salt
- polymeric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000243 solution Substances 0.000 claims description 33
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 claims description 31
- 239000000203 mixture Substances 0.000 claims description 26
- -1 polymethylene chain Polymers 0.000 claims description 26
- 239000003795 chemical substances by application Substances 0.000 claims description 23
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 16
- 150000003839 salts Chemical class 0.000 claims description 14
- 239000012530 fluid Substances 0.000 claims description 12
- 239000007864 aqueous solution Substances 0.000 claims description 10
- 239000004615 ingredient Substances 0.000 claims description 9
- VAZJLPXFVQHDFB-UHFFFAOYSA-N 1-(diaminomethylidene)-2-hexylguanidine Chemical compound CCCCCCN=C(N)N=C(N)N VAZJLPXFVQHDFB-UHFFFAOYSA-N 0.000 claims description 8
- 229940079593 drug Drugs 0.000 claims description 7
- 239000003814 drug Substances 0.000 claims description 7
- 230000000844 anti-bacterial effect Effects 0.000 claims description 6
- 239000003899 bactericide agent Substances 0.000 claims description 6
- 229920000642 polymer Polymers 0.000 claims description 6
- 125000004122 cyclic group Chemical group 0.000 claims description 3
- 239000003889 eye drop Substances 0.000 claims description 3
- 239000012756 surface treatment agent Substances 0.000 claims description 3
- 230000002411 adverse Effects 0.000 claims description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 2
- 231100001035 ocular change Toxicity 0.000 claims description 2
- 229910052760 oxygen Inorganic materials 0.000 claims description 2
- 239000001301 oxygen Substances 0.000 claims description 2
- 229920006395 saturated elastomer Polymers 0.000 claims description 2
- 125000004434 sulfur atom Chemical group 0.000 claims description 2
- 239000002562 thickening agent Substances 0.000 claims description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 10
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 8
- 238000002474 experimental method Methods 0.000 description 7
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 6
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 6
- 239000007924 injection Substances 0.000 description 6
- 238000002347 injection Methods 0.000 description 6
- 206010010726 Conjunctival oedema Diseases 0.000 description 5
- 208000006069 Corneal Opacity Diseases 0.000 description 5
- 229960000686 benzalkonium chloride Drugs 0.000 description 5
- 150000001875 compounds Chemical class 0.000 description 5
- 231100000269 corneal opacity Toxicity 0.000 description 5
- 239000012153 distilled water Substances 0.000 description 5
- CFKMVGJGLGKFKI-UHFFFAOYSA-N 4-chloro-m-cresol Chemical compound CC1=CC(O)=CC=C1Cl CFKMVGJGLGKFKI-UHFFFAOYSA-N 0.000 description 4
- 230000007794 irritation Effects 0.000 description 4
- 239000011780 sodium chloride Substances 0.000 description 4
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 3
- 206010037867 Rash macular Diseases 0.000 description 3
- 229960002152 chlorhexidine acetate Drugs 0.000 description 3
- 210000004087 cornea Anatomy 0.000 description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 3
- 201000004614 iritis Diseases 0.000 description 3
- 230000003472 neutralizing effect Effects 0.000 description 3
- 125000004433 nitrogen atom Chemical group N* 0.000 description 3
- 229920002451 polyvinyl alcohol Polymers 0.000 description 3
- 239000001103 potassium chloride Substances 0.000 description 3
- 235000011164 potassium chloride Nutrition 0.000 description 3
- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 239000012085 test solution Substances 0.000 description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 229960002242 chlorocresol Drugs 0.000 description 2
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 2
- GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical compound O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 description 2
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 2
- 235000019796 monopotassium phosphate Nutrition 0.000 description 2
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 2
- 229920001983 poloxamer Polymers 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- QCHFTSOMWOSFHM-WPRPVWTQSA-N (+)-Pilocarpine Chemical compound C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C QCHFTSOMWOSFHM-WPRPVWTQSA-N 0.000 description 1
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
- 229940123208 Biguanide Drugs 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 206010010741 Conjunctivitis Diseases 0.000 description 1
- 206010055665 Corneal neovascularisation Diseases 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical compound [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 1
- 206010015946 Eye irritation Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 229920001213 Polysorbate 20 Polymers 0.000 description 1
- QCHFTSOMWOSFHM-UHFFFAOYSA-N SJ000285536 Natural products C1OC(=O)C(CC)C1CC1=CN=CN1C QCHFTSOMWOSFHM-UHFFFAOYSA-N 0.000 description 1
- VMHLLURERBWHNL-UHFFFAOYSA-M Sodium acetate Chemical compound [Na+].CC([O-])=O VMHLLURERBWHNL-UHFFFAOYSA-M 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- 230000002924 anti-infective effect Effects 0.000 description 1
- 229940121363 anti-inflammatory agent Drugs 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 239000008346 aqueous phase Substances 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 150000004283 biguanides Chemical class 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 229920003090 carboxymethyl hydroxyethyl cellulose Polymers 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 1
- 229960005091 chloramphenicol Drugs 0.000 description 1
- WDRFFJWBUDTUCA-UHFFFAOYSA-N chlorhexidine acetate Chemical compound CC(O)=O.CC(O)=O.C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 WDRFFJWBUDTUCA-UHFFFAOYSA-N 0.000 description 1
- 229960001884 chlorhexidine diacetate Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 201000000159 corneal neovascularization Diseases 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 229940012356 eye drops Drugs 0.000 description 1
- 231100000013 eye irritation Toxicity 0.000 description 1
- 210000000744 eyelid Anatomy 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 150000003840 hydrochlorides Chemical class 0.000 description 1
- 239000002054 inoculum Substances 0.000 description 1
- 235000010445 lecithin Nutrition 0.000 description 1
- 239000000787 lecithin Substances 0.000 description 1
- 229940067606 lecithin Drugs 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000003547 miosis Effects 0.000 description 1
- 239000003604 miotic agent Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- DCNLOVYDMCVNRZ-UHFFFAOYSA-N phenylmercury(.) Chemical class [Hg]C1=CC=CC=C1 DCNLOVYDMCVNRZ-UHFFFAOYSA-N 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229960001416 pilocarpine Drugs 0.000 description 1
- 229960002139 pilocarpine hydrochloride Drugs 0.000 description 1
- RNAICSBVACLLGM-GNAZCLTHSA-N pilocarpine hydrochloride Chemical compound Cl.C1OC(=O)[C@@H](CC)[C@H]1CC1=CN=CN1C RNAICSBVACLLGM-GNAZCLTHSA-N 0.000 description 1
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920002503 polyoxyethylene-polyoxypropylene Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
- C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
- A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
- A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
- A61L12/141—Biguanides, e.g. chlorhexidine
- A61L12/142—Polymeric biguanides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Eyeglasses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1700572A GB1432345A (en) | 1972-04-13 | 1972-04-13 | Ophthalmic compositions and contact lens disinfecting compo sitions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2318137A1 true DE2318137A1 (de) | 1973-10-25 |
Family
ID=10087528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE2318137A Pending DE2318137A1 (de) | 1972-04-13 | 1973-04-11 | Mittel fuer augen beziehungsweise kontaktlinsen |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS4918043A (enExample) |
| AU (1) | AU5433573A (enExample) |
| DE (1) | DE2318137A1 (enExample) |
| FR (1) | FR2182962B1 (enExample) |
| GB (1) | GB1432345A (enExample) |
| IT (1) | IT983030B (enExample) |
| NL (1) | NL7305180A (enExample) |
| ZA (1) | ZA732395B (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3012767A1 (de) | 1980-04-02 | 1981-10-08 | Wella Ag | Kosmetische mittel |
| US4504405A (en) * | 1980-12-18 | 1985-03-12 | Smith And Nephew Associated Companies P.L.C. | Method of cleaning soft contact lenses |
| EP0055515B1 (en) | 1980-12-18 | 1985-02-20 | Smith and Nephew Associated Companies p.l.c. | Lens sterilising solutions and their use |
| JPS57190162A (en) * | 1981-05-19 | 1982-11-22 | Nissan Motor Co Ltd | Preventive mechanism of gear disengagement |
| US4537746A (en) * | 1983-12-29 | 1985-08-27 | Bausch & Lomb Incorporated | Methods for disinfecting and preserving contact lenses |
| US4758595A (en) * | 1984-12-11 | 1988-07-19 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| CA1259542A (en) * | 1984-09-28 | 1989-09-19 | Francis X. Smith | Disinfecting and preserving solutions for contact lenses and methods of use |
| US4836986A (en) * | 1984-09-28 | 1989-06-06 | Bausch & Lomb Incorporated | Disinfecting and preserving systems and methods of use |
| JPS62500661A (ja) * | 1984-09-28 | 1987-03-19 | ボ−シユ アンド ロ−ム インコ−ポレイテイド | 化粧料組成物 |
| US4783488A (en) * | 1987-01-31 | 1988-11-08 | Bausch & Lomb Incorporated | Contact lens wetting solution |
| US4891423A (en) * | 1989-03-20 | 1990-01-02 | Stockel Richard F | Polymeric biguanides |
| EP0564510A1 (en) * | 1990-12-27 | 1993-10-13 | Allergan, Inc | Method and composition for disinfecting contact lenses |
| JPH0892017A (ja) * | 1994-09-19 | 1996-04-09 | Tomey Technol Corp | コンタクトレンズ用液剤 |
| DE19604475A1 (de) * | 1996-02-08 | 1997-08-14 | Fresenius Ag | Verwendung von PHMB zur Behandlung von durch sich intrazellulär vermehrende Erreger verursachten Infektionen |
| GB9606868D0 (en) * | 1996-04-01 | 1996-06-05 | Waverley Pharma Ltd | Disinfectant solutions |
| JP3698832B2 (ja) * | 1996-10-08 | 2005-09-21 | 株式会社メニコン | コンタクトレンズ用液剤 |
| NL1005658C2 (nl) * | 1997-03-27 | 1998-09-29 | Jon Holding B V | Vloeistof voor het bewaren van contactlenzen en werkwijze voor het reinigen en spoelen van een contactlens. |
| US5965088A (en) * | 1997-10-23 | 1999-10-12 | Lever; Andrea M. | Method for providing rapid disinfection of contact lenses |
| US6153568A (en) * | 1997-11-12 | 2000-11-28 | Mccanna; David J. | Compositions comprising polyquaterniums in combination with polymeric biguanides for disinfecting contact lenses |
| CA2307664A1 (en) * | 1997-11-12 | 1999-05-20 | Bausch & Lomb Incorporated | Disinfecting contact lenses with bis(biguanides) and polymeric biguanides |
| WO1999024541A1 (en) * | 1997-11-12 | 1999-05-20 | Bausch & Lomb Incorporated | Cleaning and disinfecting contact lenses with a biguanide and a phosphate-borate buffer |
| DE69806498T2 (de) | 1997-11-12 | 2003-01-16 | Bausch & Lomb Inc., Rochester | Behandlung von kontaktlinsen mit wässrigen, alkalicarbonat-haltigen lösungen |
| CA2311659C (en) | 1997-11-26 | 2007-08-21 | Allergan Sales, Inc. | Contact lens cleaning compositions |
| US6063745A (en) * | 1997-11-26 | 2000-05-16 | Allergan | Mutli-purpose contact lens care compositions |
| FR2780641B1 (fr) | 1998-07-01 | 2000-08-11 | Oreal | Composition cosmetique et/ou dermatologique biphasee, utile notamment pour le demaquillage des yeux |
| CA2430127C (en) | 2000-11-29 | 2010-04-20 | Novartis Ag | Aqueous disinfecting system comprising a microbicide and 1,3-bis(tris[hydroxymethyl]methylamino)propane |
| US6805836B2 (en) | 2000-12-15 | 2004-10-19 | Bausch & Lomb Incorporated | Prevention of preservative uptake into biomaterials |
| TW586945B (en) | 2001-01-12 | 2004-05-11 | Novartis Ag | Lens care product containing dexpanthenol |
| CN101524554B (zh) * | 2009-04-08 | 2012-08-01 | 上海卫康光学眼镜有限公司 | 配合隐形眼镜清洁消毒使用的组合物及其应用 |
-
1972
- 1972-04-13 GB GB1700572A patent/GB1432345A/en not_active Expired
-
1973
- 1973-04-05 ZA ZA732395A patent/ZA732395B/xx unknown
- 1973-04-10 AU AU54335/73A patent/AU5433573A/en not_active Expired
- 1973-04-11 DE DE2318137A patent/DE2318137A1/de active Pending
- 1973-04-12 FR FR7313223A patent/FR2182962B1/fr not_active Expired
- 1973-04-13 NL NL7305180A patent/NL7305180A/xx unknown
- 1973-04-13 IT IT7349462A patent/IT983030B/it active
- 1973-04-13 JP JP48041498A patent/JPS4918043A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4918043A (enExample) | 1974-02-18 |
| ZA732395B (en) | 1974-03-27 |
| FR2182962B1 (enExample) | 1975-10-31 |
| AU5433573A (en) | 1974-10-10 |
| FR2182962A1 (enExample) | 1973-12-14 |
| IT983030B (it) | 1974-10-31 |
| GB1432345A (en) | 1976-04-14 |
| NL7305180A (enExample) | 1973-10-16 |
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